Comparative evaluation of abortion indicators in history of patients at the Department of Pregnancy Pathology
Taits A.N., Kharbedia Sh.D., Moiseeva K.E., Zastupova A.A.
Objective: To identify the characteristics of abortion indicators in patients at the Department of Pregnancy Pathology of the Perinatal Center, who became pregnant through IVF compared with patients who became pregnant spontaneously.
Materials and methods: Patient medical data were copied from patient registration forms N003/n003 at the Department of Pregnancy Pathology of the Perinatal Center. The main group consisted of 336 patients, who conceived through IVF. The control group comprised 394 patients, who had spontaneous pregnancy. Student's t-test was used to compare the indicators between the groups. Pearson's chi-square test was used to test the hypotheses. The results were considered statistically significant at significance level of p<0.05.
Results: The incidence of abortions in first time pregnant women was statistically significantly higher in patients in the main group compared with the control group (p=0.004). Spontaneous abortions in history occurred most often in the main group, while abortions at the request of the women predominated in the control group. Statistically significant differences were found in the distribution of patients in the main and control groups by the total number of abortions in history (χ2=11.4296; p=0.044), the number of spontaneous abortions (χ2=17.12; p=0.002), abortions due to ectopic pregnancy (χ2=39.74; p=0.000), missed miscarriage (χ2=9.93; p=0.042) and legal medical abortions (χ2=39.21; p=0.000).
Conclusion: There are significant differences in the structure and prevalence of different types of abortions in patients, who became pregnant after IVF and those, who had spontaneous pregnancy. The results of the study show the need for a differentiated approach to abortion prevention, which should be determined by the characteristics of the patient's obstetric and gynecological history.
Authors' contributions: Moiseeva K.E. – the study concept and design; Taits A.N., Zastupova A.A. – data collection and analysis; Kharbedia Sh.D., Zastupova A.A. – statistical analysis; Moiseeva K.E., Kharbedia Sh.D., Taits A.N. – manuscript writing; Moiseeva K.E., Kharbedia Sh.D. – manuscript editing.
Conflicts of interest: The authors confirm that they have no conflicts of interest to declare.
Funding: The study was conducted without any sponsorship.
Ethical Approval: This type of study does not require the expertise of the local Ethics Committee.
Patient Consent for Publication: The patients have signed informed consent for participation in the study and publication of their data.
Authors' Data Sharing Statement: The data supporting the findings of this study are available on request from the corresponding author after approval from the principal investigator..
For citation: Taits A.N., Kharbedia Sh.D., Moiseeva K.E., Zastupova A.A. Comparative evaluation of
abortion indicators in history of patients at the Department of Pregnancy Pathology.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2026; (1): 62-69 (in Russian)
https://dx.doi.org/10.18565/aig.2025.247
Keywords
pregnant women
abortions
Perinatal Center
the Department of Pregnancy Pathology
in vitro fertilization (IVF)
spontaneous pregnancy
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Received 18.09.2025
Accepted 30.12.2025
About the Authors
Anna N. Taits, PhD, Associate Professor at the Department of Obstetrics and Gynecology, Saint Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, 194100, Russia, St. Petersburg, Litovskaya str., 2, annataits1@rambler.ru, https://orcid.org/0000-0003-1084-260XShalva D. Kharbedia, PhD, Associate Professor at the Department of Public Health and Healthcare, Saint Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, 194100, Russia, St. Petersburg, Litovskaya str., 2, ozz.gpma444@mail.ru, https://orcid.org/0000-0001-8285-2917
Karina E. Moiseeva, Dr. Med. Sci., Associate Professor, Professor at the Department of Public Health and Healthcare, Saint Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, 194100, Russia, St. Petersburg, Litovskaya str., 2, karina-moiseeva@yandex.ru, https://orcid.org/0000-0002-3476-5971
Anna A. Zastupova, Teaching Assistant at the Department of Public Health and Healthcare, Saint Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, 194100, Russia, St. Petersburg, Litovskaya str., 2, prozorova-anya@mail.ru, https://orcid.org/0000-0002-0232-0388
Corresponding author: Karina E. Moiseeva, karina-moiseeva@yandex.ru
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