High-frequency ultrasound study in the diagnosis of pointed warts on the external female genitalia

Gasanova G.F., Gorbunova E.A., Saidova A.S., Dodova E.G., Belkov P.A., Bashirova L.K., Apolikhina I.A.

1 Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia 2 Anta-Med Clinic, Moscow 115114, Derbenevskaya nab. 11, Russia 3 Deparment of Obstetrics, Gynecology, Perinatology, and Reproductology, Institute of Professional Education, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia
Objective. To optimize the diagnosis of pointed warts (PWs) on the external female genitalia.
Subjects and methods. 98 patients who attended the V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, in the period from October 01, 2013 to December 01, 2014, were examined. All the women underwent high-frequency ultrasound study of the skin and mucosae of the external genitalia; extended colposcopy/vulvoscopy; photo fixation in the presence of PWs; their biopsy with subsequent morphological examination.
Results. Echo signs characteristic of this nosological entity were established; these included homogeneous hypoechoic or anechoic masses with a deformed outer contour as pyramids, waves, or ridges, which were clearly demarcated from the underlying tissues; and their lower ultrasonic density. The combination of these signs allows for the diagnosis of PWs. To verify the diagnosis of PWs needed their morphological examination. The diagnostic sensitivity of the technique was 94%; a false-positive result was noted in 6% of cases. The specificity of the method was 100%. No case of a false-negative result was seen.
Conclusion. The technique can enhance the efficiency of non-invasive diagnosis of PWs, detect subclinical lesions invisible to the naked eye, and determine the depth of the lesion on visible foci.

Keywords

high-frequency ultrasonography
pointed warts
colposcopy
papillomavirus infection

Supplementary Materials

  1. Fig. 1. Echoes of genital warts with genital warts in high-frequency ultrasound (75 MHz sensor)
  2. Fig. 2. Echoes of genital warts on high frequency ultrasound (22 MHz sensor)
  3. Fig. 3. Echoes of genital warts on high-frequency ultrasound (75 MHz)

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Received 01.03.2017

Accepted 28.04.2017

About the Authors

Gasanova Gulnar Fazilevna, postgraduate student of the Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. E-mail: g_gasanova@oparina4.ru
Gorbunova Elena Alekseevna, obstetrician-gynecologist, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. E-mail: fiestagor@gmail.com
Saidova Aina Salavdinovna, Candidate of Medical Sciences, obstetrician-gynecologist, Research Center of Obstetrics, Gynecology, and Perinatology,
Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. E-mail: a_saidova@oparina4.ru
Dodova Elena Genrikhovna, postgraduate student, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. E-mail: adeli575@mail.ru
Pavel Aleksandrovich Belkov, dermatovenereologist at the Anta-Med Clinic. 115114, Russia, Moscow, Derbenevskaya nab. 11. E-mail: pavel@antamed.ru
Bashirova Lala Kamilovna, obstetrician-gynecologist, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. E-mail: leyla9296@hotmail.com
Apolikhina Inna Anatolievna, Doctor of Medical Sciences, Head of the Department of Aesthetic Gynecology and Rehabilitation, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; Professor of the Deparment of Obstetrics, Gynecology, Perinatology, and Reproductology, Institute of Professional Education, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. E-mail: i_apolikhina@oparina4.ru

For citations: Gasanova G.F., Gorbunova E.A., Saidova A.S., Dodova E.G., Belkov P.A., Bashirova L.K., Apolikhina I.A. High-frequency ultrasound study in the diagnosis of pointed warts on the external female genitalia. Akuserstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (11): 141-7. (in Russian)
https://dx.doi.org/10.18565/aig.2017.11.141-147

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