The structural analysis of mental disorders in pregnant women with COVID‑19 pneumonia
Objective: To make a structural analysis of psychoemotional disorders in pregnant women with COVID-19 pneumonia. Hamilton Anxiety Rating ScaleAlimova Kh.P., Voitova G.A.
Materials and methods: The prospective investigation enrolled 3080 pregnant women infected with SARS-CoV-2; of them 889 were in the first trimester; 1056 and 1135 were in the second and third trimesters, respectively. The vast majority (64.3%; 1980/3080) of cases were diagnosed with moderate COVID-19 pneumonia. Psychoemotional disorders were identified and its severities were assessed using. The Hamilton Anxiety Rating Scale-7 was used to identify psychoemotional disorders and to assess their severity; posttraumatic stress disorders (PTSDs) were detected using the IES-6 and depressive syndrome was identified using the PHQ-9.
Results: A considerable part (80.1%; 2467/3080) of pregnant women during COVID-19 infection was noted to have psychoemotional disorders; with 100% (n=1056) in the second trimester of pregnancy. Depressive syndrome was evident in the first trimester, while anxiety states and PTSDs were more characteristic for the second trimester. There was a higher incidence of mixed mental disorders with the higher pregnancy status. The most of pregnant women with psychoemotional disorders (51.5%; 1585/3080) was assigned to a cohort of patients with moderate COVID-19; in the same pattern of moderate COVID-19 pneumonia, there was a preponderance of cases of PTSDs (59.5%; 1178/1980).
PTSDs showed a practically equal incidence among pregnant women with severe and very severe COVID-19 (54.3 and 52.7%, respectively), as well as anxiety (28.6 and 28.4%, respectively) and depressive (17.1 and 18.9, respectively) states. The high incidence of mixed psychoemotional disorders was characteristic for pregnant women with severe and very severe COVID-19 pneumonia (46.7 and 52.7%, respectively, which indicates the aggravation of the clinical presentations of psychoemotonal disorders during COVID-19 pneumonia progression.
Conclusion: Psychoсихоemotional disorders during COVID-19 infection are characteristic for a considerable part of pregnant women. Moreover, their early detection using specialized questionnaire scales (HARS-7, IES-6, and PHQ-9) can be favorable to the timely inclusion of a psychological component of treatment policy and prevent poor perinatal and social consequences.
Authors' contributions: Alimova Kh.P. – development of the design of the investigation, analysis of the findings, writing the text of the manuscript; Voitova G.A. – collection of data to be analyzed and their statistical processing, review of publications on the topic of the article, writing the text of the manuscript.
Conflicts of interest: The authors declare that there are no possible conflicts of interest.
Funding: The investigation has not been sponsored.
Ethical Approval: The investigation has been approved by the Ethics Committee, Republican Specialized Infectious Diseases Zangiota-1 Hospital, Ministry of Health of Uzbekistan.
Patient Consent for Publication: During the clinical trial, the patients signed an informed consent form to publication of their data.
Authors' Data Sharing Statement: The data supporting the conclusions of this investigation are available upon request from the authors.
For citation: Alimova Kh.P., Voitova G.A.
The structural analysis of mental disorders in pregnant women with COVID-19 pneumonia.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2023; (5): 100-107 (in Russian)
https://dx.doi.org/10.18565/aig.2022.208
Keywords
pregnancy
COVID-19 pneumonia
anxiety
depression
posttraumatic stress disorder
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Received 02.09.2022
Accepted 28.11.2022
About the Authors
Khilola P. Alimova, Dr. Med. Sci., Deputy Director, Republican Specialized Infectious Disease Hospital Zangiota No. 1, Khilola.Alimova69@mail.ru,https://orcid.org/0000-0001-9358-1825, 100059, Uzbekistan, Tashkent, Yakkasaroy district, Dzambula str., 6.
Gavkhar A. Voitova, M.D., obstetrician-gynecologist, perinatal psychologist, Tashkent City Center of Women's Reproductive Health; Senior Researcher,
Republican Specialized Infectious Diseases Hospital Zangiota No. 1, gavharv@mail.ru, https://orcid.org/0000-0002-7575-294X, 111805, Uzbekistan, Tashkent region, Zangiata district, K. Abdullayev str., 42.
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