Mental health and sexual function in women with premature ovarian insufficiency

Kolpakova T.G., Kochergina M.S., Averkova V.G., Yureneva S.V., Samushiya M.A.

1) Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia; 2) Central State Medical Academy, Administrative Directorate of the President of the Russian Federation, Moscow, Russia

The present review is an analysis of the current foreign and Russian literature on the problem of premature ovarian insufficiency (POI). The article provides a general overview of the etiological factors involved in disease development and the specific characteristics of the clinical picture. POI is associated with a negative impact on mood, sleep and general wellbeing and has a significant impact on quality of life, particularly on the psycho-emotional sphere and sexual function of women. The article addresses several key issues related to the impact of stress on ovarian function, the prevalence of psycho-emotional disorders among women with POI, the relationship between androgen concentration and sexual function, as well as the results of androgen therapy, according to the findings of foreign scientific publications. The paper considers the value of developing a systematic, multidisciplinary approach to the management of women with POI, which can lead to a significant improvement in their quality of life.
Conclusion: Psychological support through counselling is compulsory. Further studies are required to evaluate the efficacy and safety of testosterone therapies and to determine optimal dosages for patients with POI. This will assist in the development of an optimized treatment approach.

Authors’ contributions: Yureneva S.V., Samushiya M.A. – developing the concept and design of the study, analysis of scientific material, editing the text; Kolpakova T.G., Averkova V.G. – collecting and processing the material; Kolpakova T.G., Kochergina M.S. – writing the text. All authors made equivalent contributions to the preparation of the publication.
Conflicts of interest: Authors declare lack of the possible conflicts of interests.
Funding: The study was conducted without sponsorship.
For citation: Kolpakova T.G., Kochergina M.S., Averkova V.G., Yureneva S.V., Samushiya M.A. 
Mental health and sexual function in women with premature ovarian insufficiency.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2024; (11): 34-39 (in Russian)
https://dx.doi.org/10.18565/aig.2024.188

Keywords

premature ovarian insufficiency
POI
sexual function
androgens
testosterone
mental health
stress
anxiety
depression

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Received 01.08.2024

Accepted 12.11.2024

About the Authors

Tamara G. Kolpakova, PhD student at the Department of Gynecological Endocrinology, obstetrician-gynecologist, Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(965)245-59-66, toma-di@yandex.ru,
https://orcid.org/0000-0002-8071-5713
Maria S. Kochergina, Resident at the Department of Psychiatry, psychiatrist, Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation, 121359, Russia, Moscow, Marshal Timoshenko str., 19/1A, +7(916)743-74-99, mariakochergina.s@gmail.com, https://orcid.org/0000-0001-5011-539X
Viktoriya G. Averkova, PhD student at the Department of Gynecological Endocrinology, obstetrician-gynecologist, Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(915)259-08-10, buch1202@mail.ru,
https://orcid.org/0000-0002-8584-5517
Svetlana V. Yureneva, Dr. Med. Sci., Professor, Deputy Director for Research of the Institute of Gynecologic Oncology and Mammology, Professor at the Department of Obstetrics and Gynecology of the Department of Vocational Education, Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Oparin str., 4, +7(916)179-74-00, syureneva@gmail.com, https://orcid.org/0000-0003-2864-066X
Marina A. Samushiya, Dr. Med. Sci., Professor, Vice-Rector for Scientific Work, Head of the Department of Psychiatry, psychiatrist, psychotherapist, Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation, 121359, Russia, Moscow, Marshal Timoshenko str., 19/1A, +7(916)277-17-71,
sma-psychiatry@mail.ru, https://orcid.org/0000-0003-3681-9977
Corresponding author: Tamara G. Kolpakova, toma-di@yandex.ru

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