Hypogalactia and postpartum depression
Stenyaeva N.N., Pekareva N.A., Zubkov V.V., Chritinin D.F.
The well-being of the mother-child dyad involves a significant number of social, psychological, neuroendocrine and somatic factors.
The high risk of developing stress, anxiety and depressive disorders in a woman during the postpartum period is primarily associated with the neuroendocrine transition. Immediately after birth, the placental corticotropin-releasing hormone stops entering the bloodstream and levels of estrogen, progesterone and allopregnanolone decrease dramatically. These processes lead to the reorganization of the regulatory mechanisms of the neuroendocrine system, which determines the condition of the neurotransmitter systems of the brain responsible for the affective state of a woman.
Lactation and maternal behavior of a woman result from complex neurohumoral mechanisms. Dysregulation of these mechanisms results in both the onset of affective disorders in postpartum women and a decrease in milk production, which can lead to hypogalactia, cessation of lactation, and breastfeeding.
Supplementary feeding with NANNY goat milk formula in cases of clinically expressed hypogalactia provides the child with complete nutrition. It also helps to reduce the woman’s stress level and create conditions for the correction of hypogalactia and the restoration of breastfeeding.
Conclusion: Prevention and timely correction of stress, anxiety-depressive states in women during pregnancy and after childbirth ensure successful lactation, maternal role attainment, feelings of satisfaction and security, which are necessary for harmonious development and growth of the child.
Authors’ contributions: Stenyaeva N.N., Pekareva N.A. – concept and design, collection and processing of material, writing the text; Zubkov V.V., Chritinin D.F. – concept and design, editing.
Conflicts of interest: The authors declare that there are no conflicts of interest.
Funding: The study was conducted without sponsorship.
For citation: Stenyaeva N.N., Pekareva N.A., Zubkov V.V., Chritinin D.F. Hypogalactia and postpartum depression.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2025; (1): 127-132 (in Russian)
https://dx.doi.org/10.18565/aig.2025.12
Keywords
breastfeeding
hypogalactia
anxiety
postpartum depression
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Received 24.01.2025
Accepted 29.01.2025
About the Authors
Natalia N. Stenyaeva, Dr. Med. Sci., Senior Researcher at the Department of Andrology and Urology, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Aс. Oparina str., 4, +7(903)538-03-34, nataliasten@mail.ru,https://orcid.org/0000-0002-6495-3367
Natalia A. Pekareva, Dr. Med. Sci., Head of the Scientific Advisory Pediatric Department, Academician V.I. Kulakov, National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, +7(495)531-44-44, n_pekareva@oparina4.ru,
https://orcid.org/0000-0002-2710-864Х
Victor V. Zubkov, Dr. Med. Sci., Director of the Institute of Neonatology and Pediatrics, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4; Professor at Neonatal Department of Pediatric Faculty, I.M.Sechenov First State Medical University, Ministry of Health of Russia, 119991, Russia, Moscow, Trubetskaya str., 8-2, victor.zubkov@mail.ru, https://orcid.org/0000-0001-8366-5208
Dmitry F. Chritinin, Corresponding Member of RAS, Dr. Med. Sci., Professor at the Department of Psychiatry and Narcology, Faculty of Medicine, I.M. Sechenov
First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), 119991, Russia, Moscow, Trubetskaya str., 8-2, +7(495)609-14-00,
https://orcid.org/0000-0001-9107-2357
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