Current trends in the early diagnosis of ovarian cancer
Antonova I.B., Akopyan E.G., Aleshikova O.I., Tsallagova Z.S., Slonov A.V., Ashrafyan L.A.
Background: Despite the numerous proposed models and diagnostic algorithms, early diagnosis of ovarian cancer remains a significant challenge in modern gynecologic oncology. Solutions to this problem include the improvement of diagnostic equipment, the introduction of novel prognostic models and the use of advanced ultrasound imaging techniques.
Objective: To analyze the results of ultrasound models used in the detection of ovarian cancer in different age groups and in the implementation of screening in various risk groups, in order to create an optimal comprehensive algorithm for the early diagnosis of ovarian cancer at the primary diagnostic stage.
Materials and methods: A total of 50 publications were selected from 186 publications, including meta-analyses, reviews, and articles using PubMed.
Results: The present study investigated and compared the use of modern ultrasound models and ultrasound imaging techniques in the diagnosis of ovarian masses in different age cohorts and risk groups for the development of ovarian cancer.
Conclusion: Despite the use of new modern ultrasound models, the challenge of early diagnosis of ovarian cancer persists and makes it necessary to create a new complex algorithm with the use of additional clinical and ultrasound diagnostic methods.
Authors’ contributions: Antonova I.B. – developing the concept of the review; Aleshikova O.I. – collecting scientific material and its analysis; Akopyan E.G. – working with various sources, writing the text; Slonov A.V. – analysis of the material, writing the text, editing the article; Tsallagova Z.S. – writing the text, preparing the manuscript for publication; Ashrafyan L.A. – editing the article, approving the final version of the article.
Conflicts of interest: Authors declare lack of the possible conflicts of interest.
Funding: The study was conducted without sponsorship.
For citation: Antonova I.B., Akopyan E.G., Aleshikova O.I., Tsallagova Z.S., Slonov A.V., Ashrafyan L.A. Current trends in the early diagnosis of ovarian cancer.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2025; (2): 24-30 (in Russian)
https://dx.doi.org/10.18565/aig.2024.273
Keywords
References
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Received 30.10.2024
Accepted 30.01.2025
About the Authors
Irina B. Antonova, Dr. Med. Sci., Head of the Laboratory of Comprehensive Diagnostics and Treatment of Diseases of the Urogenital and Reproductive Systems in Adults and Children, Russian Scientific Center of Roentgenology and Radiology, Ministry of Health of Russia, 117485, Russia, Moscow, Profsoyuznaya str., 86, Iran24@yandex.ru,SPIN-code: 6247-3917; AuthorID: 698034, https://orcid.org/0000-0003-2668-2110
Elena G. Akopyan, ultrasound diagnostics doctor, Department of Ultrasound Diagnostics, Clinical and Diagnostic Center «MEDSI» on Belorusskaya, JSC «MEDSI Group of Companies», 123056, Russia, Moscow, Gruzinskiy per., 3A, lenart28@mail.ru, https://orcid.org/0009-0009-2394-6038
Zemfira S. Tsallagova, Dr. Med. Sci., Professor, Scientific Secretary, Russian Scientific Center of Roentgenology and Radiology, Ministry of Health of Russia,
117485, Russia, Moscow, Profsoyuznaya str., 86, +7(495)334-91-93, zscallagova@rncrr.ru, SPIN-code: 2242-2327, AuthorID: 468919, https://orcid.org/0000-0003-3199-0804
Olga I. Aleshikova, PhD, Senior Researcher at the Institute of Oncogynecology and Mammology, Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, olga.aleshikova@gmail.com, https://orcid.org/0000-0002-2957-3940
Andrey V. Slonov, PhD, Chief Physician, Clinical Hospital No.123 of Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of FMBA of Russia,
143007, Russia, Moscow Region, Odintsovo, Krasnogorskoye Shosse, 15, drslon83@gmail.com, https://orcid.org/0000-0003-4416-7315
Levon A. Ashrafyan, Academician of the Russian Academy of Sciences, Dr. Med. Sci., Professor, Director of the Institute of Oncogynecology and Mammology,
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow,
Ac. Oparina str., 4, SPIN-code: 4870-1626, AuthorID: 265252, https://orcid.org/0000-0001-6396-4948
Corresponding author: Elena G. Akopyan, lenart28@mail.ru