Amniotic band syndrome

Kostyukov K.V.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow, Russia
Background. Amniotic band syndrome (ABS) is a rare pregnancy complication involving a set of fetal abnormalities ranging from small annular limb constrictions to multiple malformations. ABS-induced complications depend on their location and the degree of involvement of the anatomical structure and, in case of umbilical cord compression, can result in antenatal fetal death.
Clinical case report. First-trimester ultrasonography diagnosed multiple fetal anomalies in a 25-year-old pregnant women G.; in this connection, pregnancy termination was proposed. During the procedure, transcervical fetoscopy was performed and revealed multiple bands that caused these anomalies. The fetal karyotype was normal.
Conclusion. ABS that has a variety of manifestations and similarities with severe chromosomal abnormalities presents great difficulties for prenatal diagnosis. Fetoscopy makes it possible to confirm malformations and to determine their cause.


amniotic band syndrome
prenatal diagnosis
fetal surgery


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Received 08.05.2020

Accepted 15.05.2020

About the Authors

Kirill V. Kostyukov, MD, PhD, senior researcher, Fetal Medicine Unit, doctor of the Ultrasound and Functional Diagnosis Department, Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia. Tel.: +7(926)214-97-84. E-mail:
117997, Russia, Moscow, Oparina str., 4.

For citation: Kostyukov K.V. Amniotic band syndrome.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2020; 10: 204-209 (in Russian)

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