Amniotic band syndrome
Background. Amniotic band syndrome (ABS) is a rare pregnancy complication involving a set of fetal abnormalities ranging from small annular limb constrictions to multiple malformations. ABS-induced complications depend on their location and the degree of involvement of the anatomical structure and, in case of umbilical cord compression, can result in antenatal fetal death.Kostyukov K.V.
Clinical case report. First-trimester ultrasonography diagnosed multiple fetal anomalies in a 25-year-old pregnant women G.; in this connection, pregnancy termination was proposed. During the procedure, transcervical fetoscopy was performed and revealed multiple bands that caused these anomalies. The fetal karyotype was normal.
Conclusion. ABS that has a variety of manifestations and similarities with severe chromosomal abnormalities presents great difficulties for prenatal diagnosis. Fetoscopy makes it possible to confirm malformations and to determine their cause.
Keywords
amniotic band syndrome
prenatal diagnosis
fetoscopy
fetal surgery
References
- Torpin R. Amniochorionic mesoblastic fibrous strings and amniotic bands: associated constricting fetal malformations or fetal death. Am. J. Obstet. Gynecol. 1965; 91: 65-75. https://dx.doi.org/10.1016/0002-9378(65)90588-0.
- Walter J.H., Gross L.R., Lazzara A.T. Amniotic band syndrome. J. Foot Ankle Surg. 1998; 37(4): 325-33. https://dx.doi.org/10.1016/s1067-2516(98)80070-7.
- Lockwood C., Ghidini A., Romero R., Hobbins J.C. Amniotic band syndrome: reevaluation of its pathogenesis. Am. J. Obstet. Gynecol. 1989; 160(5, Pt. 1): 1030-3. https://dx.doi.org/10.1016/0002-9378(89)90153-1.
- Quintero R.A., Morales W.J., Phillips J., Kalter C.S., Angel J.L. In utero lysis of amniotic bands. Ultrasound Obstet. Gynecol. 1997; 10(5): 316-20. https://dx.doi.org/10.1046/j.1469-0705.1997.10050316.x.
- Streeter G.L. Focal deficiencies in fetal tissues and their relation to intrauterine amputations. Contrib. Embryol. Carnegie Inst. Wash. 1930; 22(126): 1-44.
- Derderian S.C., Iqbal C.W., Goldstein R., Lee H., Hirose S. Fetoscopic approach to amniotic band syndrome. J. Pediatr. Surg. 2014; 49(2): 359-62. https://dx.doi.org/10.1016/j.jpedsurg.2013.05.013.
- Harrison M., Brosnahan D., Phelan E., Fitzgerald R.J., Reardon W. Septo-optic dysplasia with digital anomalies - a recurrent pattern syndrome. Am. J. Med. Genet. 2004; 131(1): 82-5. https://dx.doi.org/10.1002/ajmg.a.30309.
- Kondo S., Schutte B.C., Richardson R.J., Bjork B.C., Knight A.S., Watanabe Y. et al. Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nat. Genet. 2002; 32(2): 285-9. https://dx.doi.org/10.1038/ng985.
- McGrath J.A., Duijf P.H., Doetsch V., Irvine A.D., de Waal R., Vanmolkot K.R. et al. Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. Hum. Mol. Genet. 2001; 10(3): 221-9. https://dx.doi.org/10.1093/hmg/10.3.221.
- Barrow L.L., van Bokhoven H., Daack-Hirsch S., Andersen T., van Beersum S.E., Gorlin R. et al. Analysis of the p63 gene in classical EEC syndrome, related syndromes, and non-syndromic orofacial clefts. J. Med. Genet. 2002; 39(8): 559-66. https://dx.doi.org/10.1136/jmg.39.8.559.
- McGuirk C.K., Westgate M.N., Holmes L.B. Limb deficiencies in newborn infants. Pediatrics. 2001; 108(4): E64. https://dx.doi.org/10.1542/peds.108.4.e64.
- Paladini D., Foglia S., Sglavo G., Martinelli P. Congenital constriction band of the upper arm: the role of three-dimensional ultrasound in diagnosis, counseling and multidisciplinary consultation. Ultrasound Obstet. Gynecol. 2004; 23(5): 520-2. https://dx.doi.org/ 10.1002/uog.1042.
- Михайлов А.В., Романовский А.Н., Константинова T.A., Княнксеп A.Н., Кузнецов A.A., Шлыкова А.В., Княнксеп И.В., Мовчан В.Е., Базаров И.Р. Использование 3D-эхографии и фетоскопии при синдроме амниотических тяжей. Вопросы реконструктивной и пластической хирургии. 2018; 21(4): 79-84. [Mikhailov A.V., Romanovsky A.N., Konstantinova T.A., Knyanksep A.N., Kuznetsov A.A., Shlykova A.V., Knyanksep I.V., Movchan V.E., Bazarov I.R. Use of 3D-echography and fetoscopy in amniotic cord syndrome. Questions of reconstructive and plastic surgery. 2018; 21(4): 79-84. (in Russian)]. https://dx.doi.org/10.17223/1814147/67/10.
- Tadmor O.P., Kreisberg G.A., Achiron R., Porat S., Yagel S. Limb amputation in amniotic band syndrome: serial ultrasonographic and Doppler observations. Ultrasound Obstet. Gynecol. 1997; 10(5): 312-5. https://dx.doi.org/ 10.1046/j.1469-0705.1997.10050312.x.
- Heifetz S.A. Strangulation of the umbilical cord by amniotic bands: report of 6 cases and literature review. Pediatr. Pathol. 1984; 2(3): 285-304. https://dx.doi.org/10.3109/15513818409022261.
- Crombleholme T.M., Dirkes K., Whitney T.M., Alman B., Garmel S., Connelly R.J. Amniotic band syndrome in fetal lambs I: fetoscopic release and morphometric outcome. J. Pediatr. Surg. 1995; 30(7): 974-8. https://dx.doi.org/10.1016/0022-3468(95)90324-0.
Received 08.05.2020
Accepted 15.05.2020
About the Authors
Kirill V. Kostyukov, MD, PhD, senior researcher, Fetal Medicine Unit, doctor of the Ultrasound and Functional Diagnosis Department, Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia. Tel.: +7(926)214-97-84. E-mail: kostyukov_k@yahoo.com.117997, Russia, Moscow, Oparina str., 4.
For citation: Kostyukov K.V. Amniotic band syndrome.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2020; 10: 204-209 (in Russian)
https://dx.doi.org/10.18565/aig.2020.10.204-209
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