Prediction of specific complications of monochorionic multiple pregnancy in the first trimester

Kostyukov K.V., Sakalo V.A., Gladkova K.A.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow, Russia
Objective. To assess the role of echographic markers of the first trimester in predicting specific complications of monochorionic multiple pregnancy.
Subjects and methods. A retrospective cohort study was conducted in 143 pregnant women with monochorionic diamniotic twins who underwent an echographic study in the first trimester of pregnancy.
Results. The study revealed a statistically significant relationship of the development of complications to the following echographic parameters, such as collar space thickness (CST), blood flow pulsatility index in the venous duct, coccyx-parietal size discordance, and fetal abdominal circumference.
Conclusion. This study based on the analysis of first-trimester screening results in patients with monochorionic multiple pregnancies allows identification of a group of high-risk pregnant women who need closer monitoring for timely diagnosis and treatment.

Keywords

multiple pregnancy
monochorionic twin
feto-fetal transfusion syndrome
selective intrauterine growth restriction
first-trimester screening
fetal surgery
intrauterine surgery
fetoscopy
prenatal diagnosis

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Received 12.02.2019

Accepted 22.02.2019

About the Authors

Kirill V. Kostyukov, MD, Ph.D., Doctor of Functional and Ultrasound Diagnostics, Department of Visual Diagnostics, Federal State Budgetary Institution National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakova ”of the Ministry of Health of Russia,
tel .: +7 (926) 2149784, e-mail: kostyukov_k@yahoo.com; 117997, Russia, Moscow, ul. Ak. Oparina, d. 4.
Victoria A. Sakalo, graduate student, obstetrician-gynecologist of the 2nd maternity ward, Federal State Budgetary Institution National Medical Research Center of Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakova, Ministry of Health of Russia, tel .: +7 (929) 5887208, e-mail: v_sakalo@oparina4.ru;
117997, Russia, Moscow, ul. Ak. Oparina, d. 4.
Kristina A. Gladkova, MD, Senior Researcher, Department of Fetal Medicine, Federal State Budgetary Institution National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakova “of the Ministry of Health of Russia, tel .: +79163211007, e-mail: k_gladkova@oparina4.ru;
117997, Russia, Moscow, ul. Ak. Oparina, d. 4.

For citation: Kostyukov K.V., Sakalo V.A., Gladkova K.A. Prediction of specific complications of monochorionic multiple pregnancy in the first trimester.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2019; 12: 36-44. (In Russian).
https://dx.doi.org/10.18565/aig.2019.12.36-44

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