Application of continuous amnioinfusion via a subcutaneous port system for premature rupture of membranes and at less than 28 weeks of gestation. The first experience in Russia
Premature rupture of membranes (PROM) is one of the major causes of high neonatal mortality and morbidity. Very preterm PROM, fetal pulmonary hypoplasia, and fetal inflammatory response syndrome are associated with the loss of amniotic fluid and the development of oligo/anhydramnios.Tskhai V.B., Naberezhnev Yu.I., Chirikov M.N., Lobanova T.T., Dudina A.Yu., Golovchenko O.V.
Objective. To extend the duration of pregnancy prolongation without increasing the infection risk with continuous amnioinfusion via a subcutaneous port system.
Materials and methods. A patient with PROM at 25 weeks’ gestation had continuous amnioinfusion (100 ml/h, 2400 ml/day, SDP (4±2 cm)) via a subcutaneous port, by using a hypotonic solution by the properties similar to those of amniotic fluid.
Conclusion. The first experience with continuous amnioinfusion allowed us to increase the interval of pregnancy prolongation up to 10 days in PROM. This new method can certainly be used in pregnant women with PROM and oligo/anhydramnios at term < 28/0 weeks of gestation.
Keywords
oligo/anhydramnios
amnioinfusion
premature rupture of membranes
preterm labor
Supplementary Materials
- Fig. 1. Port system for continuous amnioinfusion
- Fig. 2. Ultrasound monitoring of the port system for continuous amnioinfusion
- Fig. 3. Micro flora composition in the pregnant at 22-28 gestation age with preterm water discharge (n = 32)
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Received 16.08.2017
Accepted 22.09.2017
About the Authors
Tskhay Vitaly B., MD., prof., Head of Department of Perinatology, Obstetrics and Gynecology, Medical Faculty, Krasnoyarsk State Medical University namedafter V.F. Voyno-Yasenetsky. 660022, Russia, Krasnoyarsk, P. Zheleznyaka str. 1. Tel.: +79232872134. E-mail: tchai@yandex.ru
Naberezhnev Yury I., M.D., senior researcher, Department of Genetics, Cytology and Bioengineering, Voronezh State University. 394018, Russia, Voronezh,
Universitetskaya pl. 1. Tel.: +79103231247. E-mail: rubick@yandex.ru
Tchirikov Michael N., Prof. MD, PhD, Director of Department of Obstetrics and Prenatal Medicine, Center of Fetal Surgery, University Hospital Halle (Saale),
Martin Luther University Halle-Wittenberg, Halle (Saale), Germany, Ernst-Grube Strasse 40, DE-06120. E-mail: michael.tchirikov@uk-halle.de
Lobanova Tatjana T., Head of Department of Ultrasound and Functional diagnostics, Krasnoyarsk Regional Clinical Center of Maternity and Childhood.
600074, Russia, Krasnoyarsk, Academician Kirensky str. 2A. Теl.: +79131974868. E-mail: oufd_pc@pericentr.ru
Dudina Anna Yu., assistant of Department of Perinatology, Obstetrics and Gynecology, Medical Faculty, V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Obstetrician-gynecologist of Department of Pregnancy Pathology Unit №1. Krasnoyarsk Regional Clinical Center of Maternity and Childhood.
660022, Russia, Krasnoyarsk, P. Zheleznyaka str. 1. Tel.: +79131974868. E-mail: anybar@mail.ru
Golovchenko Oleg V., M.D., Associate Professor, Department of Obstetrics and Gynecology Medical Faculty, Belgorod National Research University.
308015, Russia, Belgorod, Pobeda str. 85. Tel.: +79103258807. E-mail: capit68@mail.ru
For citations: Tskhai V.B., Naberezhnev Yu.I., Chirikov M.N., Lobanova T.T., Dudina A.Yu., Golovchenko O.V. Application of continuous amnioinfusion via a subcutaneous port system for premature rupture of membranes and at less than 28 weeks of gestation. The first experience in Russia. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (12): 141-7. (in Russian)
https://dx.doi.org/10.18565/aig.2017.12.141-147
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