The first experience with radical trachelectomy with uterine transposition in a patient with stage IB2 cervical cancer
Background. The priority direction of modern oncology is the development and introduction of organ-sparing treatments in cancer patients of reproductive age.Chernyshova A.L., Antipov V.A., Kolomiets L.A., Chernov V.I., Gyunter V.E., Marchenko E.S., Chekalkin T.L.
Case report. The paper describes the first clinical experience with complex organ-sparing treatment according to the radical program for stage IB invasive cervical cancer in a reproductive-aged patient. A set of therapeutic measures has been proposed to ensure the functional safety of the uterus and appendages in the patient with cervical cancer who needs combination treatment, i.e. extended surgery followed by radiation or chemoradiotherapy to the pelvic area. The main technical technique was the uterine and appendage transposition that was performed as part of radical abdominal trachelectomy and could remove the utero-ovarian complex from the radiation load zone.
In addition, the uterine locking apparatus was intraoperatively formed using a shape-memory implant made of titanium nickelide. The follow-up lasted 10 months and showed a satisfactory oncological efficacy.
Conclusion. Thus, the described clinical case shows that organ-sparing surgery can be performed as part of comprehensive treatment using the radical program in a reproductive-aged patient with invasive cervical cancer.
Keywords
cervical cancer
trachelectomy
uterine transposition
implant
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Received 23.06.2020
Accepted 06.11.2020
About the Authors
Alyena L. Chernyshova, Dr. Med. Sci., Professor of the RAS, leading researcher, Gynecology Department, Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, Russia. E-mail: alacher@list.ru. ORCID: 0000-0002-8194-2811. Author ID (Scopus): 55220758100. Reseacher ID (WOS): C-8608-2012. SPIN-code: 2522-7513. 634009, Russia, Tomsk, Kooperativny str., 5.Vitaly A. Antipov, Dr. Med. Sci., Head of Department of Female Reproductive System, Municipal Clinical Hospital No 24, Moscow, Russia. E-mail: gkb24@zdrav.mos.ru. ORCID: 0000-0003-3522. Author ID (Scopus): 7005104470. 127015, Russia, Moscow, Leninskie Gory, 1-53.
Larisa A. Kolomiets, Dr. Med. Sci., Professor, Head of Gynecology Department, Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, Russia; Professor of the Department of Oncology, Siberian State Medical University. Е-mail: KolomietsLA@oncology.tomsk.ru.
ORCID: 0000-0002-6854-8940. Author ID (Scopus): 7004921120. Reseacher ID (WOS): C-8573-2012. 634009, Russia, Tomsk, Kooperativny str., 5.
Vladimir I. Chernov, Dr. Med. Sci., Professor, Deputy Director for Research and Innovation, Head of Nuclear Medicine Department, Cancer Research Institute,
Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, Russia; Leading researcher at Tomsk Polytechnic University.
Е-mail: chernov@oncology.tomsk.ru. ORCID: 0000-0002-5524-9546. SPIN-код: 6301-3612. Researcher ID (WOS): B-6789-2016. Author ID (Scopus): 7201429550.
634009, Russia, Tomsk, Kooperativny str., 5.
Viktor E. Gyunter, Dr. Tech. Sci., Professor, Director of Research Institute of Medical Materials and Shape-Memory Implants, Tomsk Russia. Е-mail: tc77@mail2000.ru. ORCID: 0000-0002-6803-5934.WoS Researcher ID: T-1762-2017. Scopus Author ID: 6701858261. 634045, Russia, Tomsk, Gvardeiskoy Divizii str., 17.
Ekaterina S. Marchenko, PhD in Technical Science, senior researcher, Research Institute of Medical Materials and Shape-Memory Implants, Tomsk Russia.
Е-mail: 89138641814@mail.ru. ORCID: 0000-0003-4615-5270. WoS Researcher ID: E-9914-2017. Scopus Author ID: 24832211500.
634045, Russia, Tomsk, Gvardeiskoy Divizii str., 17.
Timofei L. Chekalkin, PhD in Technical Science, senior researcher, Research Institute of Medical Materials and Shape-Memory Implants, Tomsk Russia,
R&D Center, Kang and Park Medical Co., Ochang, Korea. Е-mail: tc77@mail2000.ru. ORCID: 0000-0003-4615-5270. 634045, Russia, Tomsk, Gvardeiskoy Divizii str., 17.
For citation: Chernyshova A.L., Antipov V.A., Kolomiets L.A., Chernov V.I., Gyunter V.E., Marchenko E.S., Chekalkin T.L. The first experience with radical trachelectomy with uterine transposition in a patient with stage IB2 cervical cancer.
Akusherstvo i Ginekologiya/ Obstetrics and Gynecology. 2021; 3: 204-209 (in Russian)
https://dx.doi.org/10.18565/aig.2021.3.204-209
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