Characteristics of risk factors for dementia in women: a possible preventive role of menopausal hormone therapy

Yureneva S.V., Ilyina L.M.

1 National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia; 2 Association of Gynecological Endocrinologists, Moscow, Russia
Objective. To analyze the data available in modern literature on the characteristics of risk factors for dementia in women and on the possible preventive role of menopausal hormone therapy (MHT).
Material and methods. The review includes the data of Russian and Pubmed foreign articles published on this topic mainly in the past 5 years.
Results. The characteristics of risk factors for different forms of dementia in women versus men are described and the current view on the possible preventive role of MHT is outlined.
Conclusion. MHT should not be prescribed only to prevent cognitive decline and dementia, but can play a protective role in selecting the optimal timing and treatment regimen.


Alzheimer’s disease
risk factors for dementia in women
menopausal hormone therapy


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Received 16.02.2018

Accepted 02.03.2018

About the Authors

Yureneva Svetlana Vladimirovna, MD, senior researcher in Department of gynecological endocrinology of National Medical Research Center of Obstetrics, Gynecology,
and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79161797400. E-mail:
Ilina Lilia Mikhailovna, PhD, secretary of Association of gynecologists and endocrinologists.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79152101931. E-mail:

For citations: Yureneva S.V., Ilyina L.M. Characteristics of risk factors for dementia in women: a possible preventive role of menopausal hormone therapy. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (4): 28-34. (in Russian)

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