Maternal hemodynamics and preeclampsia
The paper includes scientific publications (mainly systematic reviews and meta-analyses) by foreign and Russian authors over the past 10 years, which have been found in the Pubmed database and on other available search platforms, such as Cochrane, Web of Science, MedLine, and Google Scholar, based on which the paper generalizes and updates the existing data on the features of maternal hemodynamics in preeclampsia (PE), the possibility of its early prediction and choice of therapy, by taking into consideration the indicators of the maternal cardiovascular system. It presents the possibilities of studying maternal hemodynamics using its current indicators, as well as new approaches to elucidating its role in the pathogenesis of early and late PE and data on the possible effect of the endothelial glycocalyx on the hemodynamic profile of a pregnant woman. Further studies are needed to stratify women according to their hemodynamic profile, by simultaneously investigating the endothelial glycocalyx in order to elucidate the role of maternal hemodynamics in the genesis of PE and by elaborating individualized therapeutic approaches.Nagoev T.M., Muminova K.T., Khodzhaeva Z.S., Kholin A.M., Ziganshina M.M., Kozlova A.A., Martirosyan Ya.O.
Keywords
hemodynamics
pregnancy
augmentation index (Aix)
aortic pulse wave velocity (PWV)
stiffness index
endothelial glycocalyx
antihypertensive therapy
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Received 19.06.2019
Accepted 21.06.2019
About the Authors
Temirlan M. Nagoev, Postdoc of High Risk Pregnancy Department «National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov» Ministry of Healthcare of Russia. Tel.: +7 (495) 438-0674. E-mail: tamn94@mail.ruAcademica Oparina st. 4, 117997, Moscow, Russia.
Kamilla T. Muminova, Junior researcher of High Risk Pregnancy Department «National Medical Research Center for Obstetrics, Gynecology and Perinatology named
after Academician V.I. Kulakov» Ministry of Healthcare of Russia. Tel.: +7 (495) 438-0674. E-mail:kamika91@mail.ru
Academica Oparina st. 4, 117997, Moscow, Russia
Zulfiya S. Khodzhaeva, MD , Professor, Head of High Risk Pregnancy Department. «National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov» Ministry of Healthcare of Russia. Tel.: +7(495)4380788. E-mail: zkhodjaeva@mail.ru
Academica Oparina st. 4, 117997, Moscow, Russia.
Alexey M. Kholin, obstetrician-gynecologist, High Risk Pregnancy Department. «National Medical Research Center for Obstetrics, Gynecology and Perinatology named
after Academician V.I. Kulakov» Ministry of Healthcare of Russia. Tel.: +7(495)4380788. E-mail: a_kholin@oparina4.ru
Academica Oparina st. 4, 117997, Moscow, Russia.
Marina M. Ziganshina, Senior researcher. Dept of clinical immunology. «National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov» Ministry of Healthcare of Russia. Tel.: +7(495)4380788. E-mail: m_ziganshina@oparina4.ru
Academica Oparina st. 4, 117997, Moscow, Russia.
Anastasiya А. Kozlova, resident of the «National Medical Research Center of Obstetrics, Gynecology and Perinatology named after Academician V.I Kulakov»
Ministry of Healthcare of Russia. Tel.: +7 (495)438-0674. E-mail: aakozlova.box@gmail.com
Academica Oparina st. 4, 117997, Moscow, Russia.
Yana O. Martirosyan, clinical resident of the Department of Obstetrics, Gynecology, Perinatology and Reproductive medicine of the Medical Faculty, I.M. SechenovFirst Moscow State Medical University (Sechenov University), Ministry of Health of Russia. Tel.: +7(916)950-0745. E-mail marti-yana@index.ru
117997, Russian, Moscow, Ac. Oparina str. 4
For citation: Nagoev T.M., Muminova K.T., Khodzhaeva Z.S., Kholin A.M., Ziganshina M.M., Kozlova A.A., Martirosyan Ya.O. Maternal hemodynamics and preeclampsia.
Akusherstvo i Ginekologiya/Obstetrics and gynecology. 2020; 1: 5-11. (In Russian).
https://dx.doi.org/10.18565/aig.2020.1.5-11