ISSN 0300-9092 (Print)
ISSN 2412-5679 (Online)

Modern aspects of preconception care and management of pregnant women with endocrine disorders

Rudyakova V.S., Khripun I.A., Kuzmenko N.A.

Rostov State Medical University, Ministry of Health of Russia, Rostov-on-Don, Russia

The objective of this literature review is to summarize and present the latest data in the field of gynecological endocrinology. The application of this information in clinical practice can help to ensure the successful management of pregnant women with endocrine disorders using an interdisciplinary approach.    
The review presents the modern principles of preconception care, management of pregnant women and optimal mode of delivery for women with endocrinopathies such as hyperprolactinemia, non-classical form of congenital adrenal cortex dysfunction, hyper- and hypothyroidism. Preconception care of women with these extragenital pathologies should begin long before pregnancy preceded by long-term and stable treatment of endocrine disease. This approach reduces the risk of pregnancy complications. The management of pregnant women with endocrine disorders requires special attention and a coordinated interdisciplinary approach from obstetricians, gynecologists and endocrinologists.
Conclusion: The rate of endocrine infertility is high. However, conception and successful pregnancy can be achieved with proper preconception care and management of pregnant women that should be guided not only by obstetricians and gynecologists, but also endocrinologists and other specialists. 

Authors’ contributions: Rudyakova V.S., Khripun I.A., Kuzmenko N.A. – developing the concept and subject of the article; Rudyakova V.S. – the analysis of the literature, writing the text; Khripun I.A., Kuzmenko N.A. – editing the article.
Conflicts of interest: Authors declare lack of the possible conflicts of interests.
Funding: The study was conducted without sponsorship.
For citation: Rudyakova V.S., Khripun I.A., Kuzmenko N.A. Modern aspects of preconception care and 
management of pregnant women with endocrine disorders.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2025; (7): 12-17 (in Russian)
https://dx.doi.org/10.18565/aig.2025.62

Keywords

preconception care
pregnancy
endocrinopathies
interdisciplinary approach

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Received 06.03.2025

Accepted 04.04.2025

About the Authors

Victoria S. Rydyakova, clinical resident at the Department of Obstetrics and Gynecology No. 3, Rostov State Medical University, Ministry of Health of Russia,
344022, Russia, Rostov-on-Don, Nakhichevansky lane, 29, +7(938)486-50-43, rydyakova.v@mail.ru, https://orcid.org/0000-0002-6708-3686
Irina A. Khripun, Dr. Med. Sci., Professor, Department of Endocrinology (with a course of pediatric endocrinology), Rostov State Medical University,
Ministry of Health of Russia, 344022, Russia, Rostov-on-Don, Nakhichevansky lane, 29, +7(903)436-47-44, khripun.irina@gmail.com, https://orcid.org/0000-0003-0284-295X
Natalia A. Kuzmenko, Associate Professor at the Department of Endocrinology (with a course of pediatric endocrinology), Rostov State Medical University,
Ministry of Health of Russia, 344022, Russia, Rostov-on-Don, Nakhichevansky lane, 29, +7(928)213-46-85, natalia-kuzmenko@yandex.ru,
https://orcid.org/0000-0002-2767-4959
Corresponding author: Victoria S. Rydyakova, rydyakova.v@mail.ru

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