Pregnancies with successful delivery after radical trachelectomy in a patient with cervical cancer
Popov V.V., Moshurov I.P., Redkin A.N., Popov Ya.V., Popova A.A., Porotkova O.V.
Background: According to statistics, cervical cancer is one of the most common neoplastic diseases affecting women both in the world and in the Russian Federation. At the same time, there has been an increase in the number of patients of reproductive age. In this regard, the issue of organ preservation treatment of cervical cancer and extending the patient’s reproductive potential without compromising oncological efficacy becomes relevant. The method of radical trachelectomy (RT) is appropriate for this condition. RT is already included in international treatment standards, but it requires the accumulation of clinical experience.
Case report: A 25-year-old patient was diagnosed with stage IB1 (T1N0M0) cervical cancer. Considering the early stage of the disease, the young age of the patient, and her desire to preserve her fertility, organ-sparing surgery with combined laparoscopic and vaginal access was chosen as the preferred treatment option. Over the next 10 years, the patient did not experience any relapses or malignancies. She was able to become pregnant three times, once through IVF and twice naturally, with two successful deliveries by cesarean section.
Conclusion: The presented case demonstrates that performing organ-sparing RT in case of cervical cancer provides an opportunity of successful and even multiple childbirth in the future without the progression of malignant neoplastic diseases.
Authors’ contributions: Popov V.V. – collecting information; Popova A.A. – processing information; Moshurov I.P., Porotkova O.V. – developing the concept and design of the study; Popov Ya.V. – writing the text; Redkin A.N. – editing the text.
Conflicts of interest: Authors declare lack of the possible conflicts of interest.
Funding: The study was conducted without sponsorship.
Patient Consent for Publication: The patient signed informed consent for the publication of her data.
For citation: Popov V.V., Moshurov I.P., Redkin A.N., Popov Ya.V., Popova A.A., Porotkova O.V.
Pregnancies with successful delivery after radical trachelectomy in a patient with cervical cancer.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2025; (12): 183-186 (in Russian)
https://dx.doi.org/10.18565/aig.2025.109
Keywords
reproductive potential
cervical cancer
radical trachelectomy
organ-sparing surgery
pregnancy
oncological gynecology
quality of life
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Received 24.04.2025
Accepted 26.08.2025
About the Authors
Vadim V. Popov, PhD, Head of the Gynecology Department, Voronezh Regional Scientific and Clinical Oncology Center, 394000, Russia, Voronezh, Vaitsekhovskogo str., 4, +7(473)257-95-70, popov_vadim@mail.ruIvan P. Moshurov, Dr. Med. Sci., Chief Physician, Voronezh Regional Scientific and Clinical Oncology Center, 394000, Russia, Voronezh, Vaitsekhovskogo str., 4;
Chief Freelance Oncologist at the Department of Health of the Voronezh Region; Head of the Department of Oncology, N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia, 394000, Russia, Voronezh, Studencheskaya str., 10, +7(473)253-08-68, moshurov@vokod.vrn.ru
Alexander N. Redkin, Dr. Med. Sci., Professor at the Department of Oncology, N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia, 394000, Russia, Voronezh, Studencheskaya str., 10, +7(473)253-01-06, oncology@vsmaburdenko.ru
Yaroslav V. Popov, first year resident at the Oncology Department, N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia,
394000, Russia, Voronezh, Studencheskaya str., 10, +7(950)778-79-77, yarik_popov-v_00@bk.ru, https://orcid.org/0009-0001-0379-3849
Anastasia A. Popova, first year resident at the Oncology Department, N.N. Burdenko Voronezh State Medical University, Ministry of Health of Russia,
394000, Russia, Voronezh, Studencheskaya str., 10, +7(919)168-20-88, nastya_solo202002@mail.ru, https://orcid.org/0000-0002-3904-9253
Oksana V. Porotkova, PhD, Hematologist, Voronezh Regional Clinical Hospital No. 1, 394000, Russia, Voronezh, Moskovsky Ave., 151, +7(903)851-60-23,
popova_oxanav@mail.ru
Corresponding author: Anastasia A. Popova, nastya_solo202002@mail.ru
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