Сlinical characteristics of Syrian women with uterine leiomyoma
Alali O.M., Khaddam W.M., Churnosov M.I.
Objective: To analyze the clinical characteristics, risk factors, and impact on lifestyle of women with uterine leiomyomas (ULs) and compare these findings with a control group of healthy women.
Materials and methods: Conducted from June 2023 to August 2024, the study included 1,000 Syrian women (500 patients with ULs and 500 controls) aged 22–83 from various cities. A questionnaire formed of 65 questions containing information about the clinical characteristics and risk factors for the development of uterine leiomyomas was used. Data was analyzed using Statistical Packages for Software Sciences (SPSS) version 30.
Results: Revealed significant differences between patients and controls in age at first menstruation (p=0.046), length of the menstrual cycle (p=0.016), duration of the menstrual bleeding (p=0.043), age at menopause (p<0.001), time elapsed since the last birth (p<0.001), and endometrial ablation (p=0.039). Regarding the characteristics of the Fibrous nodes, it indicated that submucosal fibroids were in only 6/500 (1.2%) women, while pedunculated was in 22/500 (4.4%) women, subserosal was in 227/500 (45.4%), and intramural was in 228/500 (45.6%).
Conclusion: This study demonstrated which clinical characteristics and risk factors for uterine leiomyomas were statistically significant in Syrian women. This may help determine the best techniques to diagnose and treat them well in order to prevent complications and reduce their impact on health-related quality of life.
Authors' contributions: Alali O.M., Khaddam W.M., Churnosov M.I. – conception and design of the study; Alali O.M. – data collection and analysis, manuscript drafting; Churnosov M.I. – manuscript editing.
Conflicts of interest: The authors have no conflicts of interest to declare.
Funding: There was no funding for this study.
Ethical Approval: The study was reviewed and approved by the Research Ethics Committee of the Belgorod State National Research University.
Patient Consent for Publication: All patients provided informed consent for the publication of their data.
Authors' Data Sharing Statement: The data supporting the findings of this study are available upon request from the corresponding author after approval from the principal investigator.
For citation: Alali O.M., Khaddam W.M., Churnosov M.I.
Сlinical characteristics of Syrian women with uterine leiomyoma.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2025; (7): 76-83 (in Russian)
https://dx.doi.org/10.18565/aig.2025.59
Keywords
uterine leiomyoma
fibroids
characteristics
clinical features
risk factors
Syria
Syrian women
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Received 05.03.2025
Accepted 17.06.2025
About the Authors
Ola Mohamad Alali, PhD student, Belgorod State National Research University, 85 Pobedy str., 308015, Belgorod, Russia, alali@bsuedu.ru,https://orcid.org/0000-0003-4370-6719
Walid Khaddam, Doctor of Microbiology, Homs University, Homs, Syria, wkhaddam@homs-univ.edu.sy, https://orcid.org./0000-0001-6771-2211
Mikhail I. Churnosov, Dr. Med. Sci., Professor, Head of the Department of Medical and Biological Disciplines, Belgorod National Research University, 85 Pobedy str.,
308015, Belgorod, Russia, churnosov@bsuedu.ru, https://orcid.org/ 0000-0003-1254-6134
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