The endemicity of an area in terms of micronutrient deficiencies as a criterion for compounding a basic vitamin-mineral complex for the periconceptional period

Shikh E.V., Makhova A.A.

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow 119991, Bolshaya Pirogovskaya str. 2, bld. 4, Russia
The authors have carried out a systems analysis of the data available in the current literature on the effect of micronutrients, such as iodine, polyunsaturated fatty acids, folic acid, and vitamin D, on a woman’s reproductive health. Due to its geographical location, climatic features, and eating habits, our country has the proven deficiency of a number of micronutrients that play an important role in the periconceptional period. These micronutrients include iodine, polyunsaturated fatty acids, folic acid, and vitamin D. The content of micronutrients should not exceed the physiological daily requirement in the basic complexes intended for the prevention of deficiency, The excessive content of components can cause undesirable reactions and contribute to the allergization of newborns. In clinically pronounced deficiency, the basal complex can be combined with a monocomponent vitamin preparation for the targeted correction of vitamin and mineral status.

Keywords

vitamin D
iodine
folic acid
polyunsaturated fatty acids
basic complex

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Received 22.08.2018

Accepted 21.09.2018

About the Authors

Shikh, Evgenia V., MD, Professor, Head of the Department of Clinical Pharmacology and Propedeutics of Internal Diseases, I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia. 119991, Russia, Moscow, Bolshaya Pirogovskaya str. 2, bld. 4. E-mail: chih@mail.ru
Makhova, Anna A., PhD, Associate Professor of the Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, I.M. Sechenov First Moscow State
Medical University (Sechenov University), Ministry of Health of Russia. 119991, Russia, Moscow, Bolshaya Pirogovskaya str. 2, bld. 4. E-mail: annabramova@gmail.com

For citations: Shikh E.V., Makhova A.A. The endemicity of an area in terms of micronutrient deficiencies as a criterion for compounding a basic vitamin-mineral complex for the periconceptional period. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (10): 25-32. (in Russian)
https://dx.doi.org/10.18565/aig.2018.10.25-32

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