Synchronous endometrial cancer of uterine hemi-cavities in uterus didelphys
Shumeikina A.O., Krasilnikov S.E., Makiyan Z.N., Samoylova E.A.
Rationale. Endometrial cancer associated with uterine anomalies is extremely rare and is characterized by high diagnostic complexity. A comprehensive assessment of uterine cavities is crucial for gynecological practice, as it identifies the extent of the lesion and the appropriate treatment strategy.
Case report. A case study describes of a 68-year-old female patient with complete duplication of the uterus and incomplete duplication of the vagina, who was diagnosed with synchronous endometrial cancer of uterine hemi-cavities (FIGO IB and IIIA). Preoperative imaging (MRI, ultrasound) made it possible to diagnose a tumor only in the right hemi-uterus, while involvement of the left hemi-cavity was only confirmed by postoperative morphological examination. A total hysterectomy of both uterine hemi-cavities and adnexa was performed followed by adjuvant radiation therapy.
Conclusion. The obtained results highlight the need for separate diagnostic curettage of uterine hemi-cavities in cases of complete uterine duplication and demonstrates the feasibility of using a comprehensive preoperative examination algorithm (3D ultrasound, MRI, hysteroscopy) to optimize oncological outcomes.
Authors' contributions. Krasilnikov S.E., Shumeikina A.O., Makiyan Z.N., Samoylova E.A. – surgical treatment, study concept and design, data collection, analysis of the obtained results, manuscript writing and editing.
Conflicts of interest. The authors declare no conflicts of interest.
Funding. This research received no external funding.
Generative Artificial Intelligence. No generative artificial intelligence technologies were used to prepare this article.
Patient Consent for Publication. The patient provided a written informed consent for publication of her data and associated images.
For citation: Shumeikina A.O., Krasilnikov S.E., Makiyan Z.N., Samoylova E.A.
Synchronous endometrial cancer of uterine hemi-cavities in uterus didelphys.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2026; (8): 208-214 (in Russian)
https://dx.doi.org/10.18565/aig.2025.319
Keywords
endometrial neoplasms
uterus didelphys
synchronous tumors
endometrioid adenocarcinoma
preoperative diagnosis
hysteroscopy
three-dimensional ultrasonography
magnetic resonance imaging
hysterectomy
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Received 07.11.2025
Accepted 15.04.2026
About the Authors
Anastasia O. Shumeikina, Junior Researcher, Institute of Oncology and Neurosurgery, E.N. Meshalkin National Medical Research Center, 15 Rechkunovskaya str., Novosibirsk, 630055, Russia; PhD Student, Federal Research Center for Fundamental and Translational Medicine, 2 Timakova str., Novosibirsk, 630060, Russia, nashum99@mail.ru,https://orcid.org/0009-0008-1839-071X
Sergey E. Krasilnikov, Dr. Med. Sci., Professor, Chief Researcher, Federal Research Center for Fundamental and Translational Medicine, 2 Timakova str., Novosibirsk,
630060, Russia; Professor, Department of Obstetrics and Gynecology, Novosibirsk State University, 2 Pirogova str., Novosibirsk, 630090, Russia; Deputy Chief Physician
for Research, AvisMed LLC, 86 Krasny Prospect, Novosibirsk, 630005, Russia, https://orcid.org/0000-0003-0687-0894
Zograb N. Makiyan, Dr. Med. Sci., Leading Researcher, Department of Operative Gynecology, V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 4 Ac. Oparina str., Moscow, 117997, Russia, makiyan@mail.ru, https://orcid.org/0000-0002-0463-1913
Elena A. Samoylova, PhD, Head of the Department of Radiotherapy, Radiologist, E.N. Meshalkin National Medical Research Center, 15 Rechkunovskaya str., Novosibirsk, 630055, Russia, e_samoylova@nricp.ru, https://orcid.org/0000-0002-1507-9992
Corresponding author: Anastasia O. Shumeikina, nashum99@mail.ru
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