Vulvodynia: a modern view on the pathogenetic mechanisms of development and the principles of treatment

Bakhtiyarov K.R., Khizhnyakov V.T., Belogubova S.Yu., Kazakova D.A.

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russia
The review article covers the definition of vulvodynia, its possible causes, the pathogenetic mechanisms of development, and the specific principles of treatment. The main factors contributing to disease development are comorbidity, other pain syndromes in the history, chronic inflammation, pelvic floor muscle hypertonicity, genetic, neurological factors, and psychosocial problems. Due to the multivariate pathogenesis of vulvodynia in each patient, interdisciplinary and personalized approaches that affect the mechanism of disease development, as well as a search for new specific treatments should be considered as the principles of treatment. These methods are the application of botulinum toxin type A, platelet-rich blood plasma, hyaluronic acid, and placental preparations along with developing physiotherapy treatments.

Keywords

vulvodynia
dyspareunia
vulvar pain
botulinum toxin
plasma therapy
physiotherapy

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Received 19.02.2019

Accepted 22.02.2019

About the Authors

Bahtiyarov Kamil’ Rafaehl’evich, MD, Professor, Professor of the Department of Obstetrics, Gynecology, and Perinatology of the Faculty of Medicine of I.M. Sechenov
First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); chief specialist, doctor of the highest category,
curator of the direction «Obstetrics and Gynecology» «Klinika semejnaya» of LLC “Family Medical Centers Network”
Address: 119991, Moscow, ul. Trubetskaya, 8/2. Phone: +7 (910) 440-30-39, E-mail: doctorbah@mail.ru
Hizhnyakova Viktoriya Tofikovna, obstetrician-gynecologist, doctor of ultrasound diagnostics «Klinika semejnaya» of LLC «Family Medical Centers Network»
Address: 119991, Moscow, ul. Trubetskaya, 8/2. E-mail: +7 (916) 804-26-47, E-mail: victorya.05@mail.ru
Belogubova Sofiya Yuryevna, a 6th year student of the International School «Medicine of the Future» of the Faculty of Medicine of I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Address: 119991, Moscow, ul. Trubetskaya, 8/2. Phone: +7 (926) 600-46-19. E-mail: belogubovasofia@gmail.com
Kazakova Dar’ya Andreevna, a 6th year student of the International School «Medicine of the Future» of the Faculty of Medicine of I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Address: 119991, Moscow, ul. Trubetskaya, 8/2. Phone: +7 (903) 288-97-64. E-mail: kazakova.daria@gmail.com

For citation: K.R. Bahtiyarov, V.T. Hizhnyakova, S.YU. Belogubova, D.A. Kazakova. New insights into the pathogenesis and treatment of vulvodynia Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2019; (6): 5-13 (in Russian)
https://dx.doi.org/10.18565/aig.2019.6.5-13

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