About
The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
ArchiveEthical StandardsSubscription
For authors
InstructionsInformed consent policyContract offerEASE GuidelinesICJME CriteriaWAME Recommendations on ChatGPT and Chatbots in Relation to Scholarly Publications
Reviewing
About
The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
ArchiveEthical StandardsSubscription
For authors
InstructionsInformed consent policyContract offerEASE GuidelinesICJME CriteriaWAME Recommendations on ChatGPT and Chatbots in Relation to Scholarly Publications
Reviewing
Logout
Obstetrics and Gynegology2019№10
The sexual health of gynecologic...

The sexual health of gynecologic cancer patients

DOI
https://dx.doi.org/10.18565/aig.2019.10.75-80

Solopova A.G., Dadak C., Vlasina A.Yu., Moskvicheva V.S., Idrisova L.E., Makatsariya A.D., Blbulyan T.A.

1) I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Moscow, Russia; 2) University Clinic of Obstetrics and Gynecology, Vienna, Austria; 3) Mkhitar Heratsi Yerevan State Medical University, Yerevan, Armenia
Every year there is an increasing number of women with malignant neoplasms of the reproductive system. The problems that emerge during the diagnosis and treatment of cancer of female genital organs cause limitations in the implementation of sexual function, which negatively affects the physical and mental status of patients, lowering their quality of life. To date, insufficient attention has been paid to the sexual health of gynecologic cancer patients, although intimacy disorders, such as female sexual dysfunctions, are detected in most of them. This literature review analyzes foreign and Russian publications on the sexual health of patients with the most common types of gynecologic cancer. It presents the research results published in Pubmed, eLIBRARY, and Google Scholar over the past 10 years.

Keywords

gynecologic oncology
sexual health
sexual function
female sexual dysfunction
quality of life
Full text (in Russian)

References

  1. Minig L., Padilla-Iserte P., Zorrero C. The relevance of gynecologic oncologists to provide high-quality of care to women with gynecological cancer. Front. Oncol. 2016; 5: 308. https://doi.org/10.3389/fonc.2015.00308.
  2. Каприн А.Д., Старинский В.В., Петрова Г.В., ред. Злокачественные новообразования в России в 2018 году (заболеваемость и смертность). М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России; 2019. 236 c. [Kaprin A.D., Starinskij V.V., Petrova G.V., red. Zlokachestvennye novoobrazovanija v Rossii v 2018 godu (zabolevaemost’ i smertnost’). M.: MNIOI im. P.A. Gercena – filial FGBU «NMIC radiologii» Minzdrava Rossii. 2019; 236 c.(In Russian)].
  3. Bray F., Ferlay J., Soerjomataram I., Siege R.L., Torre L.A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 2018; 68(6): 394-424. https://doi.org/10.3322/caac.21492.
  4. Всемирная организация здравоохранения. Вопросы здравоохранения. Сексуальное здоровье. [Vsemirnaja organizacija zdravoohranenija. Voprosy zdravoohranenija. Seksual’noe zdorov’e. (In Russian)]. Available at: https://www.who.int/topics/sexual_health/ru/
  5. Drglin Z. Female sexuality and medicine – Sexualisation of everyday life, desexualisation of childbirth. In: Mivsek A.P., ed. Sexology and midwifery. London: IntechOpen Limited; 2015: 143-63. https://doi.org/10.5772/60124.
  6. Huffman L.B., Hartenbach E.M., Carter J., Rash J.K., Kushner D.M. Maintaining sexual health throughout gynecologic cancer survivorship: a comprehensive review and clinical guide. Gynecol. Oncol. 2016; 140(2): 359-68. https://doi.org/10.1016/j.ygyno.2015.11.010.
  7. Ворник Б.М., Коган М.И., Кришталь Е.В., Ромащенко О.В. Женская сексология и сексопатология. 2-е изд. М.: ГЭОТАР-Медиа; 2017. 432 с. [Vornik B.M., Kogan M.I., Krishtal’ E.V., Romashhenko O.V. Zhenskaja seksologija i seksopatologija. 2-e izd. M.: GJeOTAR-Media; 2017. 432 s. (In Russian)].
  8. The International Statistical Classification of Diseases and Related Health Problems. 10th revision (ICD-10). Available at: https://icd.who.int/browse10/2010/en
  9. Reed G.M., Drescher J., Krueger R.B., Atalla E., Cochran S.D., First M.B. et al. Disorders related to sexuality and gender identity in the ICD‐11: revising the ICD-10 classification based on current scientific evidence, best clinical practices, and human rights considerations. World Psychiatry. 2016; 15(3): 205-21. https://doi.org/10.1002/wps.20354.
  10. Small W.Jr., Bacon M.A., Bajaj A., Chuang L.T., Fisher B.J., Harkenrider M.M. et al. Cervical cancer: a global health crisis. Cancer. 2017; 123(13): 2404-12. https://doi.org/10.1002/cncr.30667.
  11. Vermeer W.M., Bakker R.M., Kenter G.G., Stiggelbout A.M., ter Kuile M.M. Cervical cancer survivors’ and partners’ experiences with sexual dysfunction and psychosexual support. Support. Care Cancer. 2016; 24(4): 1679-87. https://doi.org/10.1007/s00520-015-2925-0.
  12. Pieterse Q.D., Kenter G.G., Maas C.P., de Kroon C.D., Creutzberg C.L., Trimbos J.B.M.Z. et al. Self-reported sexual, bowel and bladder function in cervical cancer patients following different treatment modalities: longitudinal prospective cohort study. Int. J. Gynecol. Cancer. 2013; 23(9): 1717-25. https://doi.org/10.1097/IGC.0b013e3182a80a65.
  13. American Cancer Society. Cancer treatment & survivorship facts & figures 2016-2017. Atlanta: American Cancer Society; 2016.
  14. Maiorino M.I., Chiodini P., Bellastella G., Giugliano D., Esposito K. Sexual dysfunction in women with cancer: a systematic review with meta-analysis of studies using the Female Sexual Function Index. Endocrine. 2016; 54(2): 329-41. https://doi.org/10.1007/s12020-015-0812-6.
  15. Song T., Choi C.H., Lee Y.Y., Kim T.J., Lee J.W., Kim B.G., Bae D.S. Sexual function after surgery for early-stage cervical cancer: is there a difference in it according to the extent of surgical radicality? J. Sex. Med. 2012; 9(6): 1697-704. https://doi.org/10.1111/j.1743-6109.2012.02723.x.
  16. Aerts L., Enzlin P., Verhaeghe J., Poppe W., Vergote I., Amant F. Long-term sexual functioning in women after surgical treatment of cervical cancer stages IA to IB: a prospective controlled study. Int. J. Gynecol. Cancer. 2014; 24(8): 1527-34. http://dx.doi.org/10.1097/IGC.0000000000000236.
  17. Hofsjö A., Bergmark K., Blomgren B., Jahren H., Bohm-Starke N. Radiotherapy for cervical cancer – impact on the vaginal epithelium and sexual function. Acta Oncol. 2018; 57(3): 338-45. https://doi.org/10.1080/0284186X.2017.1400684.
  18. Jensen P.T., Groenvold M., Klee M.C., Thranov I., Petersen M.A., Machin D. Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer. Int. J. Radiat. Oncol. Biol. Phys. 2003; 56(4): 937-49. https://doi.org/10.1016/S0360-3016(03)00362-6.
  19. Greimel E.R., Winter R., Kapp K.S., Haas J. Quality of life and sexual functioning after cervical cancer treatment: a long-term follow-up study. Psychooncology. 2009; 18(5): 476-82. https://doi.org/10.1002/pon.1426.
  20. Mantegna G., Petrillo M., Fuoco G., Venditti L., Terzano S., Anchora L.P. et al. Long-term prospective longitudinal evaluation of emotional distress and quality of life in cervical cancer patients who remained disease-free 2-years from diagnosis. BMC Cancer. 2013; 13(1): 127. http://dx.doi.org/10.1186/1471-2407-13-127.
  21. Onujiogu N., Johnson T., Seo S., Mijal K., Rash J., Seaborne L. et al. Survivors of endometrial cancer: who is at risk for sexual dysfunction? Gynecol. Oncol. 2011; 123(2): 356-9. https://doi.org/10.1016/j.ygyno.2011.07.035.
  22. Aerts L., Enzlin P., Verhaeghe J., Poppe W., Vergote I., Amant F. Sexual functioning in women after surgical treatment for endometrial cancer: a prospective controlled study. J. Sex. Med. 2015; 12(1): 198-209. https://doi.org/10.1111/jsm.12764.
  23. Nout R.A., Smit V.T.H.B.M., Putter H., Juergenliemk-Schulz I.M., Jobsen J.J., Lutgens L.C.H.W. et al. Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial. Lancet. 2010; 375(9717): 816-23. https://doi.org/10.1016/S0140-6736(09)62163-2.
  24. Nout R.A., Putter H., Jürgenliemk-Schulz I.M., Jobsen J.J., Lutgens L.C.H.W., van der Steen-Banasik E.M. et al. Five-year quality of life of endometrial cancer patients treated in the randomised post operative radiation therapy in endometrial cancer (PORTEC-2) trial and comparison with norm data. Eur. J. Cancer. 2012; 48(11): 1638-48. https://doi.org/10.1016/j.ejca.2011.11.014.
  25. Becker M., Malafy T., Bossart M., Henne K., Gitsch G., Denschlag D. Quality of life and sexual functioning in endometrial cancer survivors. Gynecol. Oncol. 2011; 121(1): 169-73. https://doi.org/10.1016/j.ygyno.2010.11.024.
  26. Quick A.M., Seamon L.G., Abdel-Rasoul M., Salani R., Martin D. Sexual function after intracavitary vaginal brachytherapy for early-stage endometrial carcinoma. Int. J. Gynecol. Cancer. 2012; 22(4): 703-8. http://dx.doi.org/10.1097/IGC.0b013e3182481611.
  27. Damast S., Alektiar K.M., Goldfarb S., Eaton A., Patil S., Mosenkis J. et al. Sexual functioning among endometrial cancer patients treated with adjuvant high-dose-rate intra-vaginal radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 2012; 84(2): e187-93. https://doi.org/10.1016/j.ijrobp.2012.03.030.
  28. Ahmed-Lecheheb D., Joly F. Ovarian cancer survivors’ quality of life: a systematic review. J. Cancer Surviv. 2016; 10(5): 789-801. https://doi.org/10.1007/s11764-016-0525-8.
  29. Kornblith A.B., Mirabeau-Beale K., Lee H., Goodman A.K., Penson R.T., Pereira L. et al. Long-term adjustment of survivors of ovarian cancer treated for advanced-stage disease. J. Psychosoc. Oncol. 2010; 28(5): 451-69. https://doi.org/10.1080/07347332.2010.498458.
  30. Buković D., Silovski H., Silovski T., Hojsak I., Šakić K., Hrgović Z. Sexual functioning and body image of patients treated for ovarian cancer. Sexuality Disability. 2008; 26(2): 63-73. https://doi.org/10.1007/s11195-008-9074-z.
  31. Gershenson D.M., Miller A.M., Champion V.L., Monahan P.O., Zhao Q., Cella D. et al. Reproductive and sexual function after platinum-based chemotherapy in long-term ovarian germ cell tumor survivors: a gynecologic oncology group study. J. Clin. Oncol. 2007; 25(19): 2792-7. http://dx.doi.org/10.1200/JCO.2006.08.4590.
  32. Aerts L., Enzlin P., Verhaeghe J., Vergote I., Amant F. Psychologic, relational, and sexual functioning in women after surgical treatment of vulvar malignancy: a prospective controlled study. Int. J. Gynecol. Cancer. 2014; 24(2): 372-80. http://dx.doi.org/10.1097/IGC.0000000000000035.
  33. Barlow E.L., Hacker N.F., Hussain R., Parmenter G. Sexuality and body image following treatment for early-stage vulvar cancer: a qualitative study. J. Adv. Nurs. 2014; 70(8): 1856-66. https://doi.org/10.1007/BF01102307.
  34. de Melo Ferreira A.P., de Figueiredo E.M., Lima R.A., Cândido E.B., de Castro Monteiro M.V., de Figueiredo Franco T.M.R. et al. Quality of life in women with vulvar cancer submitted to surgical treatment: a comparative study. Eur. J. Obstet. Gynecol. Reprod. Biol. 2012; 165(1): 91-5. https://doi.org/10.1016/j.ejogrb.2012.06.027.
  35. Forner D.M., Dakhil R., Lampe B. Quality of life and sexual function after surgery in early stage vulvar cancer. Eur. J. Surg. Oncol. 2015; 41(1): 40-5. https://doi.org/10.1016/j.ejso.2014.10.050.
  36. Huffman L.B., Hartenbach E.M., Carter J., Rash J.K., Kushner D.M. Maintaining sexual health throughout gynecologic cancer survivorship: A comprehensive review and clinical guide. Gynecol. Oncol. 2016; 140(2): 359-68. https://doi.org/10.1016/j.ygyno.2015.11.010.
  37. Hazewinkel M.H., Laan E.T.M., Sprangers M.A.G., Fons G., Burger M.P.M., Roovers J.P.W.R. Long-term sexual function in survivors of vulvar cancer: a cross-sectional study. Gynecol. Oncol. 2012; 126(1): 87-92. https://doi.org/10.1016/j.ygyno.2012.04.015.

Received 03.04.2019

Accepted 04.10.2019

About the Authors

Antonina G. Solopova, MD, PhD, Professor, Department of Obstetrics and Gynecology of Children’s Health Institute, I.M. Sechenov First Moscow State
Medical University of the Ministry of Health of the Russian Federation (Sechenov University). Tel.: +7(916)6764845; e-mail: antoninasolopova@yandex.ru
Address: ul. Trubetskaya, 8-2, Moscow, Russia, 119991.
Christian Dadak, MD, Professor, University Clinic of obstetrics and gynecology, Center for teaching International postgraduate training in women‘s health.
Address: AKH, Währinger Gürtel 18-20/8C 1090 Vienna, Austria. Tel.: +43140400/29100; fax: +4314040027750. e-mail: christian.dadak@meduniwien.ac.at.
Anastasiya Yu.Vlasina, Postgraduate Student of Department of Obstetrics and Gynecology of Children’s Health Institute, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University). Tel.: +7(925)5268166;e-mail: anastasia@programist.ru
Address: ul. Trubetskaya, 8-2, Moscow, Russia, 119991.
Viktoria S. Moskvichyova, Clinical resident of Department of Sports Medicine and Rehabilitation, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University). Tel.: +7(925)1290922; e-mail: moskvicheva_viktoria@mail.ru
Address: ul. Trubetskaya, 8-2, Moscow, Russia, 119991.
Larisa E. Idrisova, PhD, Assistant of Department of Obstetrics and Gynecology of Children’s Health Institute, I.M. Sechenov First Moscow State Medical University.
Tel.: +7(925)5447008; e-mail: 5447008@mail.ru
Address: ul. Trubetskaya, 8-2, Moscow, Russia, 119991.
Aleksandr D. Makatsariya, MD, corresponding member of the Russian Academy of Sciences, Professor, Head of Department of Obstetrics and Gynecology of Children’s Health Institute, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University).
Tel.: +7(495)7885840; e-mail: gemostasis@mail.ru Address: ul. Trubetskaya, 8-2, Moscow, Russia, 119991.
Tatevik A. Blbulyan, Assistant of Department of Obstetrics and Gynecology, Yerevan State Medical University n.a. Mkhitar Heratsi; Postgraduate Student of Department of Obstetrics and Gynecology of Children’s Health Institute, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
(Sechenov University). Tel.: +7(968)9090555; e-mail: tblbulyan@gmail.com.
Address: Armeniya, Erevan 0025, ul. Koryuna, d. 2. Address: ul. Trubetskaya, 8-2, Moscow, Russia, 119991.

For citation: Solopova A.G., Dadak C., Vlasina A.Yu., Moskvicheva V.S., Idrisova L.E., Makatsariya A.D., Blbulyan T.A. The sexual health of gynecologic cancer patients.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2019; (10): 75-80. (in Russian).
http://dx.doi.org/10.18565/aig.2019.10.75-80

Similar Articles

№5 / 2023
Averkova V.G., Yureneva S.V.
Quality of life in patients with premature ovarian insufficiency treated with hormone replacement therapy
№10 / 2020
Kuznetsova I.V.
The use of phytoestrogens to improve quality of life and to preserve health in women during the menopausal transition and postmenopause
№8 / 2020
Dobrokhotova Yu.E., Kamalov А.А., Slobodyanyuk B.А., Nagieva Т.S., Khlynova S.А., Dimitrova V.I.
Characteristic features of sexual function in patients with pelvic organ prolapse
№9 / 2021
Gavrilov M.V., Puchkina G.A., Ermolenko N.S., Simacheva S.A., Sulima A.N.
Experience with the natural non-hormonal drug Serelis in the therapy of menopausal syndrome in surgical menopausal women
№3 / 2020
Lisovskaya E.V., Khilkevich E.G., Chuprynin V.D., Melnikov M.V., Ipatova M.V.
Quality of life in patients with deep infiltrating endometriosis
By continuing to use our site, you consent to the processing of cookies that ensure the proper functioning of the site.