Reproductive potential in married couple: the role of micronutrients in the preconception period

DOI

https://dx.doi.org/10.18565/aig.2024.330

Bayramova G.R., Baranov I.I., Degtyareva E.I., Ilyasova N.A.
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia

The relevance of the topic is due to declining birth rate in Russia, that is associated with social and demographic, medical and environmental factors.
The article considers the issues of the influence of micronutrients on the reproductive potential of a couple in the preconception period. Pregravid preparation including diagnosis, preventive and therapeutic measures, plays a key role in increasing fertility and reducing the risks of pregnancy complications. One of the most important issues is micronutrient deficiency, which is widespread among women and men of reproductive age. It is remarkable to note that 70–80% of women are deficient in three or more vitamins, including vitamin B, vitamin C, vitamin E, and micronutrients such as iodine, selenium and magnesium. Deficiency in these compounds negatively influences sperm quality, the process of implantation and fetal development. Taking vitamin and mineral supplements (VMS) improves fertility, has positive effect on the course of pregnancy and increases the chances of getting pregnant. Antioxidants that help to reduce oxidative stress and improve spermatogenesis are essential for men. Preparations containing L-arginine, folic acid, vitamins E and C show positive effects on sperm quality and conception probability. It should be noted that there is a need for multidisciplinary approach to pregnancy planning and importance in further research on the effects of vitamin and mineral supplements on reproductive health. These measures are aimed at increasing birth rate and improving the demographic situation in Russia.
Conclusion: Further research is needed on the effect of microelements and vitamins on improvement of reproductive function in married couples.

Authors' contributions: Bayramova G.R., Baranov I.I. – the concept and design of the study, text writing and editing; Degtyareva E.I., Ilyasova N.A. – literature search and literature sources processing, text writing.
Conflicts of interest: The authors declare that they have no conflict of interests.
Funding: The study was sponsored by pharmaceutical company “Aquion”.
For citation: Bayramova G.R., Baranov I.I., Degtyareva E.I., Ilyasova N.A. Reproductive potential in married couple: the role of micronutrients in the preconception period.
Akusherstvo i Gynekologia/Obstetrics and Gynecology. 2025; (2): 122-128 (in Russian)
https://dx.doi.org/10.18565/aig.2024.330

pregravid preparation

female infertility

male infertility

vitamin-mineral complexes

Full text (in Russian)

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Received 23.12.2024

Accepted 10.01.2025

Guldana R. Bayramova, Dr. Med. Sci., Merited Doctor of the Russian Federation, Professor at the Department of Obstetrics and Gynecology of the Department of Professional Education, Head of the Research and Outpatient Department, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow,
Ac. Oparin str., 4, +7(926)660-48-77, bayramova@mail.ru, https://orcid.org/0000-0003-4826-661X
Igor I. Baranov, Dr. Med. Sci., Professor, Head of the Scientific and Organizational Department, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia,
117997, Russia, Moscow, Ac. Oparin str., 4, +7(495)438-94-92, i_baranov@oparina4.ru, https://orcid.org/0000-0002-9813-2823
Elena I. Degtyareva, PhD, Obstetrician-Gynecologist at the Research and Outpatient Department, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia,
117997, Russia, Moscow, Ac. Oparin str., 4, +7(916)525-84-84, eidegtyareva@gmail.com, https://orcid.org/0000-0002-9813-2823
Natalya A. Ilyasova, Researcher at the Department of International Cooperation, Obstetrician-Gynecologist at the Research and Outpatient Department,
V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, natalia_ilyasova@mail.ru, 117997, Russia, Moscow, Ac. Oparin str., 4, natalia_ilyasova@mail.ru,
https://orcid.org/0000-0003-0665-3515

Reproductive potential in married couple: the role of micronutrients in the preconception period

Bayramova G.R., Baranov I.I., Degtyareva E.I., Ilyasova N.A.

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