Delayed motherhood: current possibilities of preserving the reproductive potential

Kalinina E.A., Syrkasheva A.G., Dolgushina N.V.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow
The paper analyzes the data available in the modern literature on the use of assisted reproductive technologies with cryopreservation of autologous oocytes. Oocyte vitrification is an effective fertility preservation procedure that can be used not only for medical, but also for social indications. The efficiency of oocyte vitrification depends on the patient’s age and ovarian reserve. It is necessary to further investigate this problem and to create a single register of ART cycles using vitrified autologous oocytes for the comprehensive evaluation of the efficiency and safety of the technique.


genetic material preservation
oocyte vitrification
slow oocyte freezing
assisted reproductive technologies
a patient’s age


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Received 06.04.2018

Accepted 20.04.2018

About the Authors

Kalinina, Elena A., MD, head of of the IVF Department,
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia.
117997, Moscow, Russia, Ac. Oparina str. 4. E-mail:
Syrkasheva, Anastasia G., PhD, senior researcher of the IVF Department,
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia.
117997, Moscow, Russia, Ac. Oparina str. 4. E-mail:
Dolgushina, Nataliya V., MD, head of R&D Department,
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia.
117997, Moscow, Russia, Ac. Oparina str. 4. E-mail:

For citation: Kalinina E.A., Syrkasheva A.G., Dolgushina N.V. Delayed motherhood: current possibilities of preserving the reproductive potential. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2019; (1): 56-61. (in Russian)
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