Features of medical history of women with uterine fibroids
Oboskalova T.A., Sevostyanova O.Yu., Koval M.V., Omarbekova A.T.
Objective: To study the features of the family, obstetric and gynecological as well as somatic anamnesis of women with uterine fibroids.
Materials and methods: A retrospective study of 212 case reports (2022–2025) was conducted at the multidisciplinary hospital "RZhD-Medicine" (Yekaterinburg). The study group included 117 patients with uterine fibroids, while the control group included 95 patients without uterine fibroids. Exclusion criteria included pregnancy, postmenopause, and cancer.
Results: The group with a history of uterine fibroids more often included the following pathologies: adenomyosis, endometrial hyperplasia, hydrosalpinx, endometrial polyps, cervical cysts, grade 1 obesity and a positive family history of breast cancer. Age at menarche, number of pregnancies, miscarriages, abortions, and previous deliveries, including vaginal deliveries and cesarean sections, did not show statistically significant differences between the study and the control groups. Body mass index also did not differ significantly between the compared groups.
Conclusion: The identified clinical criteria confirm the similarity of individual elements in the pathogenesis of uterine myoma, emphasizing the importance of taking into account anamnestic data when examining patients, and also allow us to identify risk groups for the development of uterine leiomyomas.
Authors’ contributions: Oboskalova T.A. – study concept, final editing; Sevostyanova O.Yu. – literature review; Koval M.V. – material analysis; Omarbekova A.T. – material collection, statistical processing.
Conflicts of interest: The authors declare no conflicts of interest.
Funding: The study had no sponsorship.
Ethical Approval: Ethics Committee approval was not required as this was a retrospective study of medical records without including any personal data of patients.
Patient Consent for Publication: Patient consent was not required, as this was a retrospective study of medical records without including any personal data of patients.
Authors' Data Sharing Statement: Data confirming the conclusion of the study is available upon the request to the corresponding author.
For citation: Oboskalova T.A., Sevostyanova O.Yu., Koval M.V., Omarbekova A.T.
Features of medical history of women with uterine fibroids.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2025; (10): 143-148 (in Russian)
https://dx.doi.org/10.18565/aig.2025.156
Keywords
uterine leiomyoma
uterine fibroids
clinical and anamnestic risk factors
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Received 16.06.2025
Accepted 15.10.2025
About the Authors
Tatyana A. Oboskalova, Dr. Med. Sci., Professor, Head of the Department of Obstetrics and Gynecology with a Course of Medical Genetics, Ural State Medical University, Ministry of Health of Russia, 620028, Russia, Yekaterinburg, Repin str., 3, oboskalova.tat@yandex.ru, https://orcid.org/ 0000-0003-0711-7896Olga Yu. Sevostyanova, Dr. Med. Sci., Professor, Department of Obstetrics and Gynecology with a Course of Medical Genetics, Ural State Medical University,
Ministry of Health of Russia, 620028, Russia, Yekaterinburg, Repin str., 3, olsyava@gmail.com , https://orcid.org/0000-0002-0828-0479
Marina V. Koval, PhD, Associate Professor, Department of Obstetrics and Gynecology with a Course of Medical Genetics, Ural State Medical University,
Ministry of Health of Russia, 620028, Russia, Yekaterinburg, Repin str., 3, marinakoval1203@gmail.com, https://orcid.org/0000-0003-1321-6583
Anastasia T. Omarbekova, Teaching Assistant, Department of Anatomy, Topographic Anatomy, Ural State Medical University, Ministry of Health of Russia, 620028, Russia, Yekaterinburg, Repin str., 3, kosova_1971@mail.ru, https://orcid.org/0009-0000-8859-5229
Corresponding author: Marina V. Koval, marinakoval1203@gmail.com
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