Main oncological aspects of the diagnosis of precancerous diseases and early stages of endometrial, cervical and ovarian malignancies

Lavrinovich O.E., Smirnova O.A., Meshkova I.E., Ul’rikh E.A., Mikaya N.A., Yakovleva M.G., Bondarev N.E., Abramova A.V., Ibragimov Z.N., Beibulatova R.M., Nekrasova E.A., Gorodnova T.V., Mikhet’ko A.A., Urmancheeva A.F., Berlev I.V., Belyaev A.M.

1) Petrov National Medical Research Center of Oncology of МMinzdrav of Russia, St. Petersburg, Russia; 2) Mechnikov North-Western State Medical University of Minzdrav of Russia, St. Petersburg, Russia
Prevention and early diagnosis of reproductive tract malignancies are one of the most important socio-medical tasks, which depends mainly on physicians’ cancer awareness and is necessary to develop an effective patient management strategy. Of greatest importance are the development and implementation of effective screening programs focused on the detection of early-stage cancers, often at an asymptomatic stage, in a practically healthy target population. These measures are aimed at cancer risk reduction, detection of early disease, and improvement in treatment strategies. Oncological preventive activities should include strengthening physicians’ cancer awareness, availability of primary care and diagnostic tests, clear patient referral guidelines, coordinating care, and timely appropriate treatment. The cancer care system is effective only if all these stages are accessible and consistent.

Keywords

screening
early diagnosis
atypical endometrial hyperplasia
cervical dysplasia
ovarian cyst
uterine cancer
cervical cancer
ovarian cancer

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Received 13.01.2020

Accepted 15.01.2020

About the Authors

Olga E. Lavrinovich, PhD, researcher at the Department of Oncogynecology, head of the department of minor surgery of the National Medical Research Center of Oncology named after N.N. Petrov of the Ministry of Health of the Russian Federation. E-mail: olgalav1973@mail.ru
Address: 197758 Russia, St. Petersburg, pos. Pesochny, st. Leningradskaya 68.
Olga A. Smirnova, MD, PhD, Oncologist at the Surgical Oncogynecology Department of the Federal State Budgetary Institution of Oncology named after N.N. Petrova Ministry of Health of Russia. Tel.:+7(921)421-13-59; Email: ssmirnova.oa@gmail.com
Address: 197758, St. Petersburg, pos. Pesochny, st. Leningradskaya, 68.
Irina E. Meshkova, PhD, oncologist of the surgical oncogynecological department of the Federal State Budgetary Institution of Oncology named after N.N. Petrova Ministry of Health of Russia. E-mail: meshkova.62@bk.ru
Address: 197758 St. Petersburg, pos. Pesochny, st. Leningradskaya, 68.
Elena A. Ulrich, MD, professor, oncologist of the surgical oncogynecological department of the Federal State Budgetary Institution of Oncology named after N.N. Petrova , Ministry of Health of Russia, Professor, Department of Oncology, Federal State Budgetary Educational Establishment of Higher Education Northwest State Medical University named after I.I. Mechnikov Ministry of Health of Russia. E-mail: elenaulrikh@yandex.ru
Address: 197758 Russia, St. Petersburg, pos. Pesochny, st. Leningradskaya 68.
191015 Russia, St. Petersburg, ul. Kirochnaya, 41.
Nikolay A. Mikaya, MD, Head of the Department of Oncogynecology, Oncologist, Surgical Oncogynecology Department of the Federal State Budgetary Institution of Oncology named after N.N. Petrova Ministry of Health of Russia. E-mail: nmikaya@mail.ru; ORCID: 0000-0002-5401-899X
Address: 197758 St. Petersburg, pos. Pesochny, st. Leningradskaya 68.
Maria G. Yakovleva, graduate student of the Scientific Department of Oncogynecology, Federal State Budgetary Institution Scientific Research Center for Oncology named after N.N. Petrova Ministry of Health of Russia. Tel.: + 7(911)813-95-44. E-mail: mersend@mail.ru; ORCID: 0000-0002-1593-6771
Address: 197758 Russia, St. Petersburg, pos. Pesochny, st. Leningradskaya 68
Nikolay E. Bondarev, PhD, senior researcher of the Department of Oncogynecology, Federal State Budgetary Institution Oncology Research Center named after N.N. Petrova Ministry of Health of Russia. Tel.: +7 (812)439-9555. Fax: +7 (812)596-8947. E-mail: oncl@rion.spb.ru
197758, St. Petersburg, pos. Pesochny, st. Leningradskaya 68.
Alina V. Abramova, Oncologist, Clinical and Diagnostic Department, Federal State Budgetary Institution Scientific Research Center for Oncology named after N.N. Petrova Ministry of Health of Russia. Tel.: +7 (812)439-9555. Fax:+7 (812)596-8947. E-mail: oncl@rion.spb.ru
Address: 197758, St. Petersburg, pos. Pesochny, st. Leningradskaya, 68.
Zaur N. Ibragimov, Candidate of Medical Sciences, Researcher, Department of Oncogynecology, Federal State Budgetary Institution Scientific Research Center for Oncology named after N.N. Petrova Ministry of Health of Russia. Tel.: +7(812)439-9555. E-mail: oncl@rion.spb.ru
Address: 197758 Russia, St. Petersburg, pos. Pesochny, st. Leningradskaya 68
Rita M. Beibulatova, clinical intern Federal State Budgetary Institution Scientific Research Center for Oncology named after N.N. Petrova Ministry of Health of the Russian Federation. Tel.:+7(812)439-9555. Fax: +7(812)596-8947. E-mail: rita.beibulatova@mail.ru
Address: 197758 St. Petersburg, pos. Pesochny, st. Leningradskaya, 68.
Ekaterina A. Nekrasova, Candidate of Medical Sciences, Researcher at the Department of Oncogynecology, Federal State Budgetary Institution National Medical Research Center for Oncology named after N.N. Petrova »Ministry of Health of Russia. Tel .: +7(812)439-9555. Fax: +7 (812) 596-8947. E-mail: ekaterina_neks@mail.ru
Tatyana V. Gorodnova, candidate of medical sciences, researcher at the Department of Oncogynecology of the Federal State Budget Scientific Institution N.M. Petrov Research Center for Oncology of the Ministry of Health of the Russian Federation. Tel.: +7 (921)305-82-18. E-mail: t.gorodnova@mail.ru; SPIN-code of the author in the RSCI: 2661-9106; ORCID: 0000-0003-1719-7498
Address: 197758 St. Petersburg, pos. Pesochny, st. Leningradskaya, 68.
Andrei A. Mikhetko, candidate of medical sciences, head of the cytology laboratory of the Federal State Budgetary Institution Scientific Research Center for Oncology named after N.N. Petrova. E-mail: amikhetko@mail.ru;
SPIN code: 3988-1947. Author ID: 932425.
Address: 197758 St. Petersburg, p. Pesochny, st. Leningradskaya 68.
Adel F. Urmancheeva, MD, professor, leading researcher at the Department of Oncogynecology, Federal State Budgetary Institution Oncology named after N.N. Petrova, Ministry of Health of Russia, Professor, Department of Oncology, Federal State Budgetary Educational Establishment of Higher Education Northwest State Medical University named after I.I. Mechnikov Ministry of Health of Russia. E-mail: adaurm@mail.ru; SPIN of the author in the RSCI: 4169-6011
Address: 197758 Russia, St. Petersburg, pos. Pesochny, st. Leningradskaya 68.
191015 Russia, St. Petersburg, ul. Kirochnaya, d. 41.
Igor V. Berlev, MD, professor, head of the scientific department of oncogynecology, Federal State Budgetary Institution Scientific Research Center for Oncology named after N.N. Petrova Ministry of Health of Russia, Head of the Department of Obstetrics and Gynecology FSBEI HE North-West State Medical University named after I.I. Mechnikov Ministry of Health of Russia. Email: iberlev@gmail.com; ORCID: 0000-0001-6937-2740
Address: 197758 St. Petersburg, pos. Pesochny, st. Leningradskaya 68
191015 St. Petersburg, ul. Kirochnaya, 41
Alexey M. Belyaev, MD, professor, director of the Federal State Budgetary Institution Oncology Research Center of Oncology named after N.N. Petrova Ministry of Health of Russia. Tel.: +7(812)439-9555. E-mail: oncl@rion.spb.ru
197758, St. Petersburg, pos. Pesochny, st. Leningradskaya, 68

For citation: Lavrinovich O.E., Smirnova O.A., Meshkova I.E., Ul’rikh E.A., Mikaya N.A., Yakovleva M.G., Bondarev N.E., Abramova A.V., Ibragimov Z.N., Beibulatova R.M., Nekrasova E.A., Gorodnova T.V., Mikhet’ko A.A., Urmancheeva A.F., Berlev I.V., Belyaev A.M. Main oncological aspects of the diagnosis of precancerous diseases and early stages of endometrial, cervical and ovarian malignancies.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2020; 1(Suppl): 5-17 (in Russian)
https://dx.doi.org/10.18565/aig.2020.1suppl.5-17

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