The nephritic mask of systemic lupus erythematosus in a pregnant woman and the birth of a baby with neonatal lupus
Background. Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease with a variety of clinical manifestations that frequently appear as a mask of various diseases. The kidneys are most commonly involved in the pathological process in SLE due to the ability to delay circulating immune complexes.Kirsanova T.V., Khodzhaeva Z.S., Kravchenko N.F., Pilia Z.A.
Case report. The paper describes a clinical case of a nephritic mask of SLE in a pregnant woman and the birth of a baby with neonatal lupus. In the multigravida with a compromised history of pregnancy loss and early preeclampsia, who had long been followed up for chronic glomerulonephritis and hypertensive syndrome, there could be an successful outcome of twin pregnancy with the birth of viable newborns due to a thorough examination for SLE as a cause of nephritic syndrome.
Conclusion. The establishment of the lupus etiology of glomerulonephritis, the presence of chronic kidney disease in the outcome of lupus nephritis concurrent with APS-associated nephropathy made it possible to optimize drug therapy and to successfully complete this pregnancy.
Keywords
neonatal lupus
congenital heart block
systemic lupus erythematosus
lupus nephritis
antiphospholipid syndrome
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Received 22.06.2020
Accepted 30.10.2020
About the Authors
Tatiana V. Kirsanova, PhD, senior researcher of the Department of Reproductive Hematology and Clinical Hemostasis, NMRC for OG&P named after Acad. V.I. Kulakov Ministry of Health of Russia. E-mail: a_tatya@mail.ru. 117997, Russia, Moscow, Ac. Oparina str., 4.Zulfiya S. Khodzhaeva, MD., Professor, Deputy Director of Obstetrics Institute, NMRC for OG&P named after Acad. V.I. Kulakov Ministry of Health of Russia.
E-mail: zkhodjaeva@mail.ru. 117997, Russia, Moscow, Ac. Oparina str., 4.
Nataliya F. Kravchenko, PhD, senior researcher of Department of Obstetrics and Extra Genital Pathology, NMRC for OG&P named after Acad. V.I. Kulakov
Ministry of Health of Russia. E-mail: n_kravchenko@oparina4.ru. 117997, Russia, Moscow, Ac. Oparina str., 4.
Zafida A. Piliya, graduate student of High Risk Pregnancy Department, NMRC for OG&P named after Acad. V.I. Kulakov Ministry of Health of Russia. E-mail: zafida@mail.ru.
117997, Russia, Moscow, Ac. Oparina str., 4.
For citation: Kirsanova T.V., Khodzhaeva Z.S., Kravchenko N.F., Pilia Z.A. The nephritic mask of systemic lupus erythematosus in a pregnant woman and the birth of a baby with neonatal lupus.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2021; 2: 168-172 (in Russian)
https://dx.doi.org/10.18565/aig.2021.2.168-172
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