Multicomponent vitamin and mineral complexes as a basis for prevention of micronutrient deficiency at reproductive age
Micronutrient supplementation is a key factor for physiological pregnancy and directly correlates with positive maternal outcomes, has a direct impact on neonatal health and subsequent development. A relationship was found between the insufficient supply of mothers with nutrients and preeclampsia, fetal growth restriction, neural tube defects, skeletal deformities, and low birth weight. Multicomponent vitamin and mineral complexes intended to use in the pregravid period, during pregnancy, and lactation allow the entry of essential micronutrients, such as iron, folates and other B vitamins, iodine, zinc, and antioxidants, into the body at the physiological daily requirements. This review presents current evidence regarding the needs for macronutrients and micronutrients during pregnancy, the risks and consequences of their deficiency, and the impact of additional exogenous intake on pregnancy outcomes.Shikh E.V., Makhova A.A.
Keywords
micronutrients
vitamin and mineral complexes
pregnancy
pregnancy outcomes
newborns
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Received 25.11.2019
Accepted 29.11.2019
About the Authors
Evgenia V. Shikh, MD, professor, head Department of Clinical Pharmacology and Propaedeutics of Internal Diseases FGAOU VO First MGMU im. I. M. Sechenovof the Ministry of Health of Russia (Sechenov University). Tel .: +7 (495)609-19-91. E-mail: chih@mail.ru; https://orcid.org/0000-0001-6589-7654.
Address: 119991, Russia, Moscow, ul. Trubetskaya, d. 8, p. 2.
Anna A. Makhova, MD, associate professor of the Department of Clinical Pharmacology and Propaedeutics of Internal Diseases FSAEI HE First MGMU named after I.M.Sechenova of the Ministry of Health of Russia (Sechenov University). Phone: +7(495) 609-19-91. Email: annabramova@gmail.com; https://orcid.org/0000-0001-9817-9886
Address: 119991, Russia, Moscow, ul. Trubetskaya, d. 8, p. 2.
For citation: Shikh E.V., Makhova A.A. Multicomponent vitamin and mineral complexes as a basis for prevention of micronutrient deficiency at reproductive age.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2020; 1: 54-62. (In Russian).
https://dx.doi.org/10.18565/aig.2020.1.54-62