Clinical and diagnostic significance of genetic predisposition to preeclampsia in the Kazakh population

1. Steegers E.A., Duvekot J.J., Pijnenborg R. Pre-eclampsia. Lancet. 2010; 376(9741): 631–44. doi: 10,.1016/S0140-6736(10)60279-6).
2. Uzan J., Carbonnel M., Piconne O., Asmar R., Ayoubi J.M. Pre-eclampsia: pathophysiology, diagnosis, and management. Vasc Health Risk Manag. 2011; 7: 467–74. doi: 10,2147/VHRM,S20181.
3. Duley L. The global impact of pre-eclampsia and eclampsia, Semin Perinatol. 2009; 33(3):130–7. doi: 10,1053/j,semperi.2009.02.010
4. Veropotveljan P.N., Veropotveljan N.P., Smorodskaja E.P., Lazarenko A.T. Modern view on the problem of pre-eclampsia. Zdorov’e Ukrainy. 2011; 6(46): 43–52. (Link: https://mazg,com,ua/ru-issue-article-470)
5. Zhao L., Bracken M.B., DeWan A.T. Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort. Ann Hum Genet. 2013; 77(4): 277-87. doi: 10,1111/ahg,12021
6. Johnson M.P., Brennecke S.P., East C.E., et al, Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene. PLoS One. 2012; 7(3): e33666. doi: 10.1371/journal.pone.0033666
7. Alkanli N., Sipahi T., Kilic T.O., Sener S. Lack of Association between ACE I/D and AGTR1 A1166C Gene Polymorphisms and Preeclampsia in Turkish Pregnant Women of Trakya Region. J Obstet Gynecol. 2014; 2(4): 49–53. doi: 10.11648/j.jgo.20140204.11
8. Elfadil G.A., Wagea A.D.I, Elmugadam A.A. Association of Angiotensinogen M235T Gene variants, and Plasma Renin Activity with Preeclampsia. Egypt Acad J Biolog Sci. 2014; 6(1): 141–9. (Link: https://www,researchgate,net/publication/265415351_Association_of_Angiotensinogen_M235T_Gene_variants_and_Plasma_Renin_Activity_with_Preeclampsia)
9. Escudero C., Roberts J.M., Myatt L., Feoktistov I. Impaired adenosine-mediated angiogenesis in preeclampsia: potential implications for fetal programming. Front Pharmacol. 2014; 5(134): 1–13. doi:10.3389/fphar.2014.00134
10. Wang X., Bai T., Liu S., Pan H., Wang B. Association between thrombophilia gene polymorphisms and preeclampsia: a meta-analysis. PLoS One. 2014; 9(6): e100789. doi:10.1371/journal.pone.0100789
11. Buurma A.J., Turner R.J., Driessen J.H., Mooyaart A.L., Schoones J.W., Bruijn J.A., et al. Genetic variants in pre-eclampsia: a meta-analysis. Hum Reprod Update. 2013; 19(3): 289–303. doi: 10,1093/humupd/dms060
12. Vitoratos N., Vrachnis N.., Iavazzo C., Kyrgiou M. Preeclampsia: molecular mechanisms, predisposition, and treatment. J Pregnancy. 2012; 2012:1–2. doi: 10.1155/2012/145487
13. Sandrim V., Palei A., Sertorio J., Cavalli R., Duarte G., Tanus-Santos J. Effects of eNOS polymorphisms on nitric oxide formation in healthy pregnancy and in pre-eclampsia. Mol Hum Reprod. 2010; 16(7): 506–10. doi: 10.1093/molehr/gaq030
14. Singh A., Sharma D., Raghunandan C., Bhattacharjee J. Role of inflammatory cytokines and eNOS gene polymorphism in pathophysiology of pre-eclampsia. Am J Reprod Immunol. 2010; 63(3): 244–51. doi: 10.1111/j.1600-0897.2009.00781.x
15. Baranov V.S. Genetic passport is fundamental for personalised and predictive medicine. Saint Petersburg: «N-L», 2009. 527 p. https://medinfo,social/uchebniki _884/geneticheskiy-pasport-osnova-individualnoy,html
16. Purcell S., Neale B., Todd-Brown K., Thomas L., Ferreira M.A., Bender D., et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007; 81(3): 559–75. doi: 10.1086/519795
17. Haram K., Mortensen J.H., Nagy B. Genetic aspects of preeclampsia and the HELLP syndrome. J Pregnancy. 2014; 2014: 910751. doi: 10.1155/2014/910751
18. Williams P., Broughton Pipkin F. The genetics of pre-eclampsia and other hypertensive disorders of pregnanc. Best Pract Res Clin Obstet Gynaecol. 2011; 25(4): 405–17. doi: 10,1016/j.bpobgyn.2011.02,007
19. Williams P.J., Morgan L. The role of genetics in pre-eclampsia and potential pharmacogenomic interventions. Pharmgenomics Pers Med. 2012; 5: 37–51. doi: 10.2147/PGPM.S23141
20. Petla L.T., Chikkala R., Ratnakar K.S., Kodati V., Sritharan V. Biomarkers for the management of pre-eclampsia in pregnant women. Indian J Med Res. 2013; 138(1): 60–7. PMID: 24056556
21. Pennington K.A., Schlitt J.M., Jackson D.L., Schulz L.C., Schust D.J. Preeclampsia: multiple approaches for a multifactorial disease. Dis Model Mech. 2012; 5(1): 9–18. doi: 10.1242/dmm,008516.
22. Szabo S., Xu Y., Romero R., Fule T., Karaszi K., Bhatti G., et al. Changes of placental syndecan-1 expression in preeclampsia and HELLP syndrome. Virchows Arch. 2013; 463(3): 445–58. doi: 10,1007/s00428-013-1426-0

Received 04.11.2019

Accepted 29.11.2019