Clinical cases of an adverse birth outcome of amniotic fluid embolism
Background. Amniotic fluid embolism, or anaphylactoid syndrome of pregnancy, is a formidable pregnancy complication that frequently results in death. The mortality rates amount to as much as 80%. This pathology accounts for 1.2 to 16.5% in the structure of maternal mortality. The risk factors may include age of over 30 years in a parturient woman; multiple pregnancy; overly strong delivery; cesarean section; uterine rupture; cervical tears; premature placental abruption; intrauterine asphyxia; and abdominal trauma. However, even the absence of risk factors does not rule out the possibility of amniotic fluid embolism.Padrul M.M., Sadykova G.K., Turova E.V.
Clinical case report. The paper describes two clinical cases of fatal amniotic fluid embolism, which demonstrate the specific features of the course of this complication in the presence and absence of risk factors.
Conclusion. Unfortunately, to date there are no clear predictors for amniotic fluid embolism that should alert the obstetricians/gynecologists when managing labor and delivery in any-risk patients.
Keywords
amniotic fluid embolism
risk factors
maternal mortality
References
- Савельева Г.М., Сухих Г.Т., Серов В.Н., Радзинский В.Е. Акушерство: национальное руководство. М.: ГЭОТАР-Медиа, 2018. 1088 с. [Savelyeva G.M., Sukhikh G.T., Serov V.N., Radzinsky V.E. Obstetrics: national leadership. M .: GEOTAR-Media, 2018.1088 s. (in Russian)]
- Возгомент О.В. О диагностике эмболии околоплодными водами. Трудный пациент. 2016; 2–3. [Vozgoment O.V. On the Diagnosis of Amniotic Fluid Embolism. Trudnyy patsiyent. 2016; 2-3: 10–15. (in Russian)]
- Макацария А.Д., Панфилова О.Ю. Эмболия околоплодными водами, или анафилактоидный синдром беременности. Практическая медицина. 2010; 43. [Makatzariya A.D., Panfilova O.J. Amniotic fluid embolism or anaphylactoid syndrome of pregnancy. Prakticheskaya meditsina. 2010; 4(43): 13–9. (in Russian)]
- Clark S.L., Hankins G.D.V., Dudley D.A., et al. Amniotic fluid embolism: analysis of national registry. Am J Obstet Gynecol. 1995; 172: 1158–67. doi: 10.1016/0002-9378(95)91474-9
- Clark S.L., Cotton D.D., Gonik B., Greenspoon J., Phelan J.P. Central hemodynamic alterations in amniotic fluid embolism. Am J Obstet Gynecol. 1988; 158:1124–26. doi: 10.1016/0002-9378(88)90236-0
- Clark S.L., Montz F.J., Phelan J.P. Hemodynamic alterations associated with amniotic fluid embolism: a reappraisal. Am J Obstet Gynecol. 1985; 151: 617–21. doi: 10.1016/0002-9378(85)90150-4
- Хорева О.П., Милованов А.П., Ковров К.Н. О патогенезе эмболии околоплодными водами (обзор литературы). Проблемы репродукции. 2006; 3: 73–5. [Khoreva O.P., Milovanov A.P., Kovrov K.N. On the pathogenesis of amniotic fluid embolism (literature review). Problemy reproduktsii. 2006; 3: 73–5. (in Russian)]
- Константинова О.Д., Мазуровская О.П., Дёмина Л.М. Эмболия околоплодными водами. Ремедиум Приволжье. 2014; 3(123): 24–29. [Konstantinova O.D., Mazurovskaya O.P., Dyomina L.M. Amniotic fluid embolism. Remedium Privolzh’ye. 2014; 3 (123): 24–29. (in Russian)]
- Dildy G.A., Belfort M.A., Clark S.L. Anaphylactoid Syndrome of Pregnancy (Amniotic Fluid Embolism). Critical Care Obstet. 2010; 466–72. doi: 10.1002/9781444316780.ch35
Received 01.10.2019
Accepted 04.10.2019
About the Authors
Mikhail M. Padrul, MD, professor, Head of the Department of Obstetrics and Gynecology, Perm State Medical University named after Academician E.A. Wagner »Ministry of Health of Russia, Perm. Tel.: +7 (908)2716466. E-mail: m-padrul@mail.ru
614990, Russia, Perm, ul. Petropavlovskaya, d. 26.
Gulnara K. Sadykova, PhD, associate professor of the Department of Obstetrics and Gynecology, Perm State Medical University named after Academician E.A. Wagner »Ministry of Health of Russia, Perm. Tel.: +7 (902) 4798742. E-mail: gulnara-sadykova@mail.ru
614990, Russia, Perm, ul. Petropavlovskaya, d. 26.
Elena V. Turova, assistant of the Department of Obstetrics and Gynecology FSBEI HE PSMU them. ac. E.A. Wagner of the Ministry of Health of Russia.
Tel.: +7 (919) 4709990. E-mail: elena_turova06@mail.ru
614990, Russia, Perm, ul. Petropavlovskaya, d. 26.
For citation: Padrul M.M., Sadykova G.K., Turova E.V. Clinical cases of an adverse birth outcome of amniotic fluid embolism.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2020; 1: 184-88. (In Russian).
https://dx.doi.org/10.18565/aig.2020.1.184-188
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