The clinical role of anatomical abnormality of the hymen

Milyukov V.Ye., Brileva E.А., Zakirova D.R., Hguen C.C.

1) Department of Human Anatomy, N.I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia; 2) I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia; 3) Yersin University, Da Lat, Viet Nam
Hymen atresia is a congenital anomaly of the female genital organs, which occurs in 1 per 1000–2,000 newborn girls.
In the paper, based on the data of modern medical literature, the authors carry out a critical analysis of the theories of vaginal embryogenesis, detailed the key stages of development of the female genital system as a whole and show the relationship of formation of the urinary and genital systems. Also, based on the cases presented in the literature, they indicate that due to the nonspecific symptoms, the detection of hymen atresia is often delayed, which leads not only to female reproductive dysfunction, but also to cardiovascular, urinary, nervous, digestive, and locomotor complications, and to unjustified surgical interventions.
Conclusion: In this connection, the authors believe that for the timely diagnosis of hymen atresia, concomitant anomalies, and complications, for the prevention of unjustified surgical interventions, it is important that practitioners should have a certain clinical alertness and a clear idea of different types of symptomatic manifestations of this congenital malformation.

Authors’ contributions: Milyukov V.Ye., Brileva E.A. – concept of the investigation; Brileva E.A., Zakirova D.R. – material collection and processing; Brileva E.A. – writing the text; Milyukov V.Ye., Nguen C.C. – editing.
Conflicts of interest: The authors of the article declare that there are no conflicts of interest.
Funding: The investigation has not been sponsored.
For citation: Milyukov V.Ye., Brileva E.А., Zakirova D.R., Hguen C.C.
The clinical role of anatomical abnormality of the hymen.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2023; (6): 142-148 (in Russian)


congenital malformations of the genital organs
obstructive female genital malformations
hymen atresia
adhesive process


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Received 30.12.2022

Accepted 31.05.2023

About the Authors

Vladimir Ye. Milyukov, Dr. Med. Sci., Professor, Department of Human Anatomy, Pirogov Russian National Research Medical University, Ministry of Health of Russia,,, 117997, Russia, Moscow, Ostrovityanov str., 1.
Elizaveta A. Brileva, student of the N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
(Sechenov University),,Х, 119991, Russia, Moscow, Trubetskaya str., 8-2.
Diana R. Zakirova, student of the N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
(Sechenov University),,, 119991, Russia, Moscow, Trubetskaya str., 8-2.
Nguyen Cao Cuong, PhD, Dean of the Faculty of Pharmacy and  Nursing, Yersin University of Da Lat of Viet Nam,,, 27, Ton That Tung str., Da Lat city, Viet Nam.
Corresponding author: Elizaveta A. Brileva,

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