Study of microbiome of female genital organs: theory and practice of the use of two-stage therapy of disbiotic diseases
The literature data on the study of the microbiota of female genital organs and assess the clinical and microbiological characteristics of the probiotic strain LCR35, used in the treatment and prevention of vaginal infections were analyzed. Biotherapeutic aspects of treatment and prevention of dysbiotic conditions of vaginal microbiota have been analyzed. A comparative evaluation of the characteristics and requirements of lactobacilli-containing preparations with probiotic activity in obstetric-gynecological practice was carried out. The clinical and microbiological advantages of the original probiotic strain Lactobacillus casei rhamnosus Doderleini (LCR35) in the formulation Lactogynal in the treatment and prevention of vaginal infections were noted. The literary review of data the medical use of the culture of Lactobacillus casei rhamnosus Doderleini (LCR35) testifies to the expediency and validity of its use in the mode of two-stage therapy of the dysbiotic conditions of the vagina. Organization and conduct of additional post-registration clinical studies of medicinal product for medical use Lactogynal will strengthen the position of targeted probiotics in the complex treatment and prevention of bacterial and fungal infections of female genital organs.Kocherovets V.I.
Keywords
vaginal microbiota
probiotics
Lactogynal
Lactobacillus casei rhamnosus Doderleini
References
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Received 08.06.2018
Accepted 22.06.2018
About the Authors
Kocherovets, Vladimir I., MD, professor of the Department of Pharmaceutical Technology and Pharmacology, Institute of Professional Training, I.M. SechenovFirst Moscow State Medical University, Ministry of Health of Russia. 119991, Russia, Moscow, Trubetskaya str. 8, bld. 2. Tel.: +79032442414. E-mail: kftif@mail.ru
For citations: Kocherovets V.I. Study of microbiome of female genital organs: theory and practice of the use of two-stage therapy of disbiotic diseases. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (8): 174-9. (in Russian)
https://dx.doi.org/10.18565/aig.2018.8.174-179
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