Vulvar basal cell carcinoma
Background. Basal cell carcinoma (BCC) is the most common human malignant tumor that accounts for as high as 75% of all malignant skin neoplasms. In all cases, BCC is associated with excessive ultraviolet insolation and is more often located on the open skin areas exposed to sunlight. Vulvar BCC is an extremely rare tumor with unknown etiology, which is asymptomatic and frequently diagnosed late.Grekova Yu.N., Voroshilina E.S., Zilberberg N.V., Kuznetsova E.I.
Case report. The paper describes a clinical case of vulvar BCC in an 87-year-old patient. The neoplasm in the perineal region appeared two months before her visit to a physician and was rounded in shape with clear boundaries of 1.5x1.0 cm. The diagnosis was confirmed by morphopathological examination.
Conclusion. The clinical case is presented for the formation of caution in dermatologists and physicians of other specialists in relation to cancers, including their rare localizations.
Keywords
basal cell carcinoma
vulva
vulvar neoplasia
References
- Siegel R.L., Miller K.D., Jemal A. Cancer statistics, 2016. CA Cancer J. Clin. 2016; 66(1): 7-30. https://dx.doi.org/10.3322/caac.21332.
- Chinem V.P., Miot H.A. Epidemiology of basal cell carcinoma. An. Bras. Dermatol. 2011; 86(2): 292-305. https://dx.doi.org/10.1590/s0365-05962011000200013.
- Mulvany N.J., Rayoo M., Allen D.G. Basal cell carcinoma of the vulva: a case series. Pathology. 2012; 44(6): 528-33. https://dx.doi.org/10.1097/PAT.0b013e328357a001.
- Benedet J.L., Miller D.M., Ehlen T.G., Bertrand M.A. Basal cell carcinoma of the vulva: clinical features and treatment results in 28 patients. Obstet. Gynecol. 1997; 90(5): 765-8. https://dx.doi.org/10.1016/S0029-7844(97)00416-X.
- de Giorgi V., Salvini C., Massi D., Raspollini M.R., Carli P. Vulvar basal cell carcinoma: retrospective study and review of literature. Gynecol. Oncol. 2005; 97(1): 192-4. https://dx.doi.org/10.1016/j.ygyno.2004.12.008.
- Mulayim N., Foster Silver D., Tolgay Ocal I., Babalola E. Vulvar basal cell carcinoma: two unusual presentations and review of the literature. Gynecol. Oncol. 2002; 85(3): 532-7. https://dx.doi.org/10.1006/gyno.2001.6582.
- Renati S., Henderson C., Aluko A., Burgin S. Basal cell carcinoma of the vulva: a case report and systematic review of the literature. Int. J. Dermatol. 2019; 58(8): 892-902. https://dx.doi.org/10.1111/ijd.14307.
- Estrada V.M., Vidrio R.M.G., Ramos Garibay A.R., Luna A.E. Carcinoma basocelular ulcerado de vulva: presenación de un caso. Rev. Cent. Dermatol. Pascua. 2003; 12(3): 123-6.
- Ernesto G., Díaz J.A., Torres S.A., Rangel C.M. Carcinoma de células basales de la vulva: reporte de un caso y revisión de la literature. Rev. Asoc. Colomb. Dermatol. Cir. Dermatol. 2007; 15(4): 286-9.
- Montesdeoca G.E., Grandal T.G., Hervas I.M., García E.R., Pruñonosa J.C.M., Torras P.B.I. Carcinoma basocelular de vulva. Prog. Obstet. Ginecol. 2014; 57: 169-71. https://dx.doi.org/10.1016/j. pog.2013.09.002.
- Reyes M.V., Pascualini M.F., Valente E., Kurpis M., Lascano A.R. Carcinoma basocelular pigmentado de vulva. Arch. Argent. Dermatol. 2009; 59: 115-7.
- Greer B.E., Koh W.J. New NCCN guidelines for vulvar cancer. J. Natl. Compr. Canc. Netw. 2016; 14(Suppl. 5): 656-8. https://dx.doi.org/10.6004/jnccn.2016.0184.
Received 03.02.2020
Accepted 07.02.2020
About the Authors
Yulia N. Grekova, Dr. Med. Sci., Associate Professor, Leading Researcher at the Department of Department of civilizacii and sexually transmitted infections, Ural Scientific Research Institute of Dermatology and Immunopatology. Tel.: +7(3432)18-33-71, +7(908)630-26-00. E-mail: kjn@mail.ru. 620076, Russia, Ekaterinburg, Shcherbakova str., 8.Ekaterina S. Voroshilina, Dr. Med. Sci., Professor at the Department of Microbiology, Virology and Immunology, Ural State Medical University, Ministry of Health of Russia. Tel.: +7(3432)14-86-52, +7(902)409-42-84. E-mail: voroshilina@gmail.com. 620028, Russia, Ekaterinburg, Repin str., 3.
Natalya V. Zilberberg, Dr. Med. Sci., Professor, Deputy Director for Science,
Ural Scientific Research Institute of Dermatology and Immunopatology. Tel.: +7(3432)18-95-70, +7(982)623-91-38. E-mail: zilberberg@mail.ru.
620076, Russia, Ekaterinburg, Shcherbakova str., 8.
Ekaterina I. Kuznetsova, the resident of the Ural State Medical University, Ministry Health of Russia. Tel.: +7(908)630-30-01. E-mail: kksk9@rambler.ru.
620028, Russia, Ekaterinburg, Repin str., 3.
For citation: Grekova Yu.N., Voroshilina E.S., Zilberberg N.V., Kuznetsova E.I. Vulvar basal cell carcinoma.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2021; 3: 201-203 (in Russian)
https://dx.doi.org/10.18565/aig.2021.3.201-203
Similar Articles
