Antenatal prevention of fetal respiratory distress syndrome: a glimpse into the future

Khodzhaeva Z.S., Gorina K.A.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow
The literature devoted to the impact of consequences of the misuse of antenatal prevention of fetal respiratory distress syndrome (RDS) and to the assessment of potential methods for its objectification has been sought and analyzed. The misuse of glucocorticosteroids affects long-term cognitive, behavioral, psychological, and physical outcomes, which is especially important, by considering that pregnancy is prolonged in 50% of women at 7-14 days after the first cycle of prevention. Functional and laboratory tests for fetal lung maturity (FLM) can avoid using drugs unreasonably for the prevention of fetal RDS. Antenatal prevention of fetal RDS is one of the most common tools in the hands of obstetricians, therefore, the issues of pre- and perinatal programming, when the diseases developed in adulthood are caused by prenatal drug loading, must be under special control.

Keywords

preterm labor
prevention of fetal respiratory distress syndrome
glucocorticosteroids
fetal lung maturity
fetal programming

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Received 30.11.2018

Accepted 07.12.2018

About the Authors

Khodzhaeva, Zulfiya S., MD, professor, head of Department of Pregnancy Pathology,
National Medical Research Center for Obstetrics, Gynecology and Perinatology
named after Academician V.I. Kulakov Ministry of Health of Russian Federation. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79164077567. E-mail: zkhodjaeva@mail.ru
Gorina, Ksenia A., junior researcher, Department of Pregnancy Pathology, National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russian Federation. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79266497732. E-mail: k_gorina@oparina4.ru

For citation: Khodzhaeva Z.S., Gorina K.A. Antenatal prevention of fetal respiratory distress syndrome: a glimpse into the future. Akusherstvo i Ginekologiya/Obstetrics and Gynecology.2019; (5): 12-8. (in Russian)
https://dx.doi.org/10.18565/aig.2019.5.12-18

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