The abilities of vitamin and mineral supplements during the COVID-19 pandemic

DOI

https://dx.doi.org/10.18565/aig.2022.5.43-52

Kodentsova V.M., Risnik D.V., Pavlovich S.V., Klimov V.A., Ladodo O.B.
1) Federal Research Center for Nutrition and Biotechnology, Moscow, Russia; 2) M.V. Lomonosov Moscow State University, Moscow, Russia; 3) Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow, Russia

The insufficient provision of micronutrients (vitamins A, D, E, C, and B-group, the minerals zinc, iron, selenium, magnesium, copper, and phosphorus) weakens the immune response, which can increase the risk of infection, contribute to disease severity and COVID-19 complications. The population of Russia, both adults and children, has deficiencies of multiple micronutrients (vitamins D, B-group, calcium, magnesium, zinc, and iodine), their simultaneous deficiency is experienced by about one third of the surveyed population. The micronutrients in the body are interconnected to form metabolic networks. A lack of one or more vitamins can disrupt the conversion of other vitamins to their biologically active forms, causing a functional vitamin deficiency. The percentage of vitamins and minerals in the diet of the population is a modifiable risk factor for infectious diseases. This implies replenishing the insufficient dietary intake of micronutrients not only to cover the needs of the body, but also to achieve their optimal provision. We are not dealing with therapy with and use of vitamins in pharmacological dosages. The intake of multivitamins provides protection against COVID-19, a decrease in the severity of the disease, a reduction in the manifestations of post-COVID sequels, and an increase in the efficiency of vaccination. Optimization of the vitamin status in all population groups through the intake of vitamin and mineral supplements (VMS) containing a complete set of vitamins and immunotropic elements is an underestimated important preventive factor in protecting from viral infections.
Conclusion: The relevance of taking VMS in pregnancy and lactation during the pandemic is becoming even more important. During the pandemic, the use of VMS by pregnant and lactating women will not only improve their own micronutrient status and subsequently optimize the percentage of vitamins and minerals in breast milk, and thus the micronutrient status of the baby, but will also contribute to the body's resistance to disease.

multiple vitamin deficiency

vitamin and mineral supplements

immunity

pregnant women

COVID-19

Full text (in Russian)

Shakoor H., Feehan J., Al Dhaher A.S., Ali H.I., Platat C., Ismail L.C. et al. Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19? Maturitas. 2021; 143: 1-9. https://dx.doi.org/10.1016/j.maturitas.2020.08.003.
Berger M.M., Herter-Aeberli I., Zimmermann M.B., Spieldenner J., Eggersdorfer M. Strengthening the immunity of the Swiss population with micronutrients: A narrative review and call for action. Clin. Nutr. ESPEN. 2021; 43: 39-48. https://dx.doi.org/10.1016/j.clnesp.2021.03.012.
DiNicolantonio J.J., O’Keefe J.H. Magnesium and vitamin D deficiency as a potential cause of immune dysfunction, cytokine storm and disseminated intravascular coagulation in COVID-19 patients. Mo Med. 2021; 118(1): 68-73.
Alexander J., Tinkov A., Strand T.A., Alehagen U., Skalny A., Aaseth J. Early nutritional interventions with zinc, selenium and vitamin D for raising anti-viral resistance against progressive COVID-19. Nutrients. 2020; 12(8): 2358. https://dx.doi.org/10.3390/nu12082358.
Gombart A.F., Pierre A., Maggini S. A review of micronutrients and the immune system–working in harmony to reduce the risk of infection. Nutrients. 2020; 12(1): 236. https://dx.doi.org/10.3390/nu12010236.
Орлова С.В., Никитина Е.А., Прокопенко Е.В., Водолазкая А.Н., Татаринов В.В., Пигарёва Ю.А. Роль витаминов и минералов в нутритивной поддержке иммунитета при COVID-19. Медицинский алфавит. 2021; 21: 12-21. [Orlova S.V., Nikitina E.A., Prokopenko E.V., Vodolazkaya A.N., Tatarinov V.V., Pigareva Yu.A. Role of vitamins and minerals in immunity support in COVID‑19. Medical Alfabet. 2021; 21: 12-21. (in Russian)]. https://dx.doi.org/10.33667/2078-5631-2021-21-12-21.
Mitra S., Paul S., Roy S., Sutradhar H., Bin Emran T., Nainu F. et al. Exploring the immune-boosting functions of vitamins and minerals as nutritional food bioactive compounds: A comprehensive review. Molecules. 2022; 27(2): 555. https://dx.doi.org/10.3390/molecules27020555.
Taheri S., Asadi S., Nilashi M., Abumalloh R.A., Ghabban N.M., Yusuf S.Y.M. et al. A literature review on beneficial role of vitamins and trace elements: Evidence from published clinical studies J. Trace Elem. Med. Biol. 2021; 67: 126789. https://dx.doi.org/10.1016/j.jtemb.2021.126789.
Asl S.H., Nikfarjam S., Zolbanin N.M., Nassiri R., Jafari R. Immunopharmacological perspective on zinc in SARS-CoV-2 infection. Int. Immunopharmacol. 2021; 96: 107630. https://dx.doi.org/10.1016/j.intimp.2021.107630.
Charoenngam N., Shirvani A., Holick M.F. Vitamin D and its potential benefit for the COVID-19 pandemic. Endocr. Pract. 2021; 27(5): 484-93. https://dx.doi.org/10.1016/j.eprac.2021.03.006.
Speakm L.L., Michienzi S.M., Badowski M.E. Vitamins, supplements and COVID-19: a review of currently available evidence. Drugs Context. 2021; 10: 2021-6-2. https://dx.doi.org/10.7573/dic.2021-6-2.
Louca P., Murray B., Klaser K., Graham M.S., Mazidi M., Leeming E.R. Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445,850 users of the COVID symptom study app. BMJ Nutr. Prev. Health. 2021; 4(1): 149-57. https://dx.doi.org/10.1136/bmjnph-2021-000250.
Abioye A.I., Bromage S., Fawzi W. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Glob. Health. 2021; 6(1): e003176. https://dx.doi.org/10.1136/bmjgh-2020-003176.
Beigmohammadi M.T., Bitarafan S., Abdollahi A., Amoozadeh L., Salahshour F., Soltani D., Motallebnejad Z.A. The association between serum levels of micronutrients and the severity of disease in patients with COVID-19. Nutrition. 2021; 91-92: 111400. https://dx.doi.org/10.1016/j.nut.2021.111400.
van Kempen T.A.T.G., Deixler E. SARS-CoV-2: influence of phosphate and magnesium, moderated by vitamin D, on energy (ATP) metabolism and on severity of COVID-19. Am. J. Physiol. Endocrinol. Metab. 2021; 320(1): E2-E6. https://dx.doi.org/10.1152/ajpendo.00474.2020.
Pecora F., Persico F., Argentiero A., Neglia C., Esposito S. The role of micronutrients in support of the immune response against viral infections. Nutrients. 2020; 12(10): 3198. https://dx.doi.org/ 10.3390/nu12103198.
Еремкина А.К., Мокрышева Н.Г., Пигарова Е.А., Мирная С.С. Витамин D: влияние на течение и исходы беременности, развитие плода и здоровье детей в постнатальном периоде. Терапевтический Архив. 2018; 90(10): 115-27. [Eremkina A.K., Mokrysheva N.G., Pigarova E.A., Mirnaya S.S. Vitamin D: effects on pregnancy, maternal, fetal and postnatal outcomes. Therapeutic Archive. 2018; 90(10): 115-27. (in Russian)]. https://dx.doi.org/10.26442/terarkh20189010115-127.
Зазерская И.Е., Дорофейков В.В., Хазова Е.Л., Беляева Е.Н., Новикова Т.В., Попова П.В., Гуркина Е.Ю. и др. Витамин D и репродуктивное здоровье женщины. Руководство; Северо-Западный федеральный медицинский исследовательский центр имени В.А. Алмазова Министерства здравоохранения Российской Федерации. Санкт-Петербург: ООО «Эко-Вектор»; 2017. 151 с. [Zazerskaya I.E., Dorofeykov V.V., Khazova E.L., Belyaeva E.N., Novikova T.V., Popova P.V., Gurkina E.Yu. et al. Vitamin D and a woman's reproductive health. Management; North-Western Federal Medical Research Center named after V.A. Almazov of the Ministry of Health of the Russian Federation. Saint Petersburg: Eco-Vector LLC; 2017. 151 p. (in Russian)].
Carr A.C., Maggini S. Vitamin C and Immune Function. Nutrients. 2017; 9(11): pii: E1211. https://dx.doi.org/10.3390/nu9111211.
Коденцова В.М., Бекетова Н.А., Никитюк Д.Б., Тутельян В.А. Характеристика обеспеченности витаминами взрослого населения Российской Федерации. Профилактическая медицина. 2018; 21(4): 32-7. [Kodentsova V.M., Beketova N.A., Nikityuk D.B., Tutelyan V.A. Characteristics of vitamin provision in the adult population of the Russian Federation. Profilakticheskaya Meditsina/The Russian Journal of Preventive Medicine. 2018; 21(4): 32-7. (in Russian)]. https://dx.doi.org/10.17116/profmed201821432.
Шейбак Л.Н. Роль и значение цинка в перинатологии. Журнал Гродненского государственного медицинского университета. 2015; 2: 30-5. [Sheybak L.N. Role and Importance of zinc in perinatology. Journal of Grodno State Medical University. 2015; 2: 30-5. (in Russian)].
Лиманова О.А., Торшин И.Ю., Сардарян И.С., Калачева А.Г., Hababpashev A., Karpuchin D., Kudrin A., Юдина Н.В., Егорова Е.Ю., Белинская А.Ю., Гришина Т.Р., Громов А.Н., Федотова Л.Э., Рудаков К.В., Громова О.А. Обеспеченность микронутриентами и женское здоровье: интеллектуальный анализ клинико-эпидемиологических данных. Вопросы гинекологии, акушерства и перинатологии. 2014; 13(2): 5-15. [Limanova O.A., Torshin I.Yu., Sardaryan I.S., Kalacheva A.G., Hababpashev A., Karpuchin D.,Kudrin A., Yudina N.V., Egorova E.Yu., Belinskaya A.N., Grishina T.R., Gromov A.N.,Fedotova L.E., Rudakov K.V., Gromova O.A. Micronutrient provision and women''s health: intellectual analysis of clinicoepidemiological data. Issues of Gynecology, Obstetrics and Perinatology. 2014; 13(2): 5-15 (in Russian)].
Name J.J., Souza A.C.R., Vasconcelos A.R., Prado P.S., Pereira C.P.M. Zinc, Vitamin D and Vitamin C: Perspectives for COVID-19 With a Focus on Physical Tissue Barrier Integrity. Front. Nutr. 2020; 7: 606398. https://doi.org/10.3389/fnut.2020.606398.
McBurney M.I., Blumberg J.B., Costello R.B., Eggersdorfer M., Erdman J.W., Harris W.S. et al. Beyond nutrient deficiency – opportunities to improve nutritional status and promote health modernizing DRIs and supplementation recommendations. Nutrients. 2021; 13(6): 1844. https://dx.doi.org/10.3390/nu13061844.
Bischoff-Ferrari H. Vitamin D – from essentiality to functionality. Int. J. Vitam. Nutr. Res. 2012, 82(5): 321-6. https://dx.doi.org/10.1024/0300-9831/a000126.
Коденцова В.М., Рисник Д.В. Микронутриентные метаболические сети и множественный дефицит микронутриентов: обоснование преимуществ витаминно-минеральных комплексов. Микроэлементы в медицине. 2020; 21(4): 3-20. [Kodentsova V.M., Risnik D.V Micronutrient metabolic networks and multiple micronutrient deficiency: a rationale for the advantages of vitamin-mineral supplements. Microelements in medicine. 2020. 21(4): 3-20 (in Russian)]. https://dx.doi.org/10.19112/2413-6174-2020-21-4.
Коденцова В.М., Погожева А.В. Группы риска множественного дефицита витаминов и минеральных веществ среди населения. Клиническое питание и метаболизм. 2020; 1(3): 34-40. [Kodentsova V.M., Pogozheva A.V. Risk groups for multiple vitamin and mineral defi ciencies in the population. Clinical nutrition and metabolism. 2020; 1(3): 34-40. (in Russian)]. https://dx.doi.org/10.17816/clinutr48744.
Коденцова В.М., Вржесинская О.А., Рисник Д.В., Никитюк Д.Б., Тутельян В.А. Обеспеченность населения России микронутриентами и возможности ее коррекции. Состояние проблемы. Вопросы питания. 2017; 86(4): 113-24. [Kodentsova V.M., Vrzhesinskaya O.A., Risnik D.V., Nikityuk D.B., Tutelyan V.A. Micronutrient status of population of the Russian Federation and possibility of its correction. State of the problem. Voprosy pitaniia/ Problems of Nutrition. 2017; 86(4): 113-24. (in Russian)]. https://dx.doi.org/10.24411/0042-8833-2017-00067.
Simon M., Pizzorno J., Katzinger J. Modifiable risk factors for SARS-CoV-2. Integr. Med. (Encinitas). 2021; 20(5): 8-14.
Ling V., Zabetakis I. The role of an anti-inflammatory diet in conjunction to COVID-19. Diseases. 2021; 9(4): 76. https://dx.doi.org/10.3390/diseases9040076.
Тутельян В.А., Никитюк Д.Б., Бурляева Е.А., Хотимченко С.А., Батурин А.К., Стародубова А.В., Камбаров А.О., Шевелева С.А., Жилинская Н.В. COVID-19: новые вызовы для медицинской науки и практического здравоохранения. Вопросы питания. 2020; 89(3): 6-13. [Tutelyan V.A., Nikityuk D.B., Burlyaeva E.A., Khotimchenko S.A., Baturin A.K., Starodubova A.V., Kambarov A.O., Sheveleva S.A., Zhilinskaya N.V. COVID-19: new challenges for medical science and practical healthcare. Voprosy pitaniia/ Problems of Nutrition. 2020. 89(3): 6-13. (in Russian)]. https://dx.doi.org/10.24411/0042-8833-20.
Calder P.C., Carr, A.C., Gombart A.F., Eggersdorfer M. Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections. Nutrients. 2020; 12: 1181. https://dx.doi.org/ 10.3390/nu12041181.
Rossato M.S., Brilli E., Ferri N., Giordano G., Tarantino G. Observational study on the benefit of a nutritional supplement, supporting immune function and energy metabolism, on chronic fatigue associated with the SARS-CoV-2 post-infection progress. Clin. Nutr. ESPEN. 2021; 46: 510-8. https://dx.doi.org/10.1016/j.clnesp.2021.08.031.
Lai Y.J., Chang H.S., Yang Y.P., Lin T.W., Lai W.Y., Lin Y.Y., Chang C.C. The role of micronutrient and immunomodulation effect in the vaccine era of COVID-19. J. Chin. Med. Assoc. 2021; 84(9): 821-6. https://dx.doi.org/10.1097/JCMA.0000000000000587.
Torshin I.Y., Gromova O.A., Chuchalin A.G. Computational systematics of nutritional support of vaccination against Viral and Bacterial Pathogens as Prolegomena to Vaccinations against COVID-19. J. Clin. Trials. 2021; 11: 478. https://dx.doi.org/10.1101/2021.09.10.21263398.
Mate A., Reyes-Goya C., Santana-Garrido Á., Sobrevia L., Vázquez C.M. Impact of maternal nutrition in viral infections during pregnancy. Biochim. Biophys. Acta. Mol. Basis Dis. 202; 1867(11): 166231. https://dx.doi.org/10.1016/j.bbadis.2021.166231.
Nawsherwan S.K., Falak Z.E.B., Shoaib M.G.N., Ijaz U.L., Kang X.U., Hui L.I. Selected micronutrients: an option to boost immunity against covid-19 and prevent adverse pregnancy outcomes in pregnant women: a narrative review. Iran. J. Public Health. 2020; 49(11): 2032-43. https://dx.doi.org/10.18502/ijph.v49i11.4717.
Sinaci S., Ocal D.F., Yetiskin D.F.Y., Hendem D.U., Buyuk G.N., Ayhan S.G. et al. Impact of vitamin D on the course of COVID-19 during pregnancy: A case control study. J. Steroid Biochem. Mol. Biol. 2021; 213: 105964. https://dx.doi.org/10.1016/j.jsbmb.2021.105964.
Бекетова Н.А., Сокольников А.А., Коденцова В.М., Переверзева О.Г., Вржесинская О.А., Кошелева О.В., Гмошинская М.В. Витаминный статус беременных женщин-москвичек: влияние приема витаминно-минеральных комплексов. Вопросы питания. 2016; 85(5): 77-85. [Beketova N.A., Sokolnikov A.A., Kodentsova V.M., Pereverzeva O.G., Vrzhesinskaya O.A., Kosheleva O.V., Gmoshinskaya M.V. The vitamin status of pregnant women in Moscow: effect of multivitamin-mineral supplements. Voprosy pitaniia/ Problems of Nutrition. 2016; 85(5): 77-85. (in Russian)].
Коденцова В.М., Рисник Д.В., Павлович С.В., Ладодо О.Б. Оптимизация обеспеченности микронутриентами кормящих женщин и новорожденных на исключительно грудном вскармливании посредством обогащения рациона женщины. Гинекология. 2021; 23(3): 222-30. [Kodentsova V.M., Risnik D.V., Pavlovich S.V., Ladodo O.B. Optimization of the micronutrients sufficiency of feeding women and children on exclusively breastfeeding by enriching of the woman diet . Gynecology. 2021; 23(3): 222-30. (in Russian)]. https://dx.doi.org/10.26442/20795696.2021.3.20087.
Громова О.А., Торшин И.Ю., Тетруашвили Н.К., Баранов И.И., Городнова Е.А., Коденцова В.М., Коган И.Ю., Тапильская Н.И., Ярмолинская М.И., Башмакова Н.В., Мозговая Е.В., Гришина Т.Р., Лапочкина Н.П., Галустян А.Н. О перспективах использования витаминов и минералов в профилактике ранних потерь беременности. Акушерство и гинекология. 2021; 4: 12-22. [Gromova O.A., Torshin I.Yu., Tetruashvili N.K., Baranov I.I., Gorodnova E.A., Kodentsova V.M., Kogan I.Yu., Tapilskaya N.I., Yarmolinskaya M I., Bashmakova N.V., Mozgovaya E.V., Grishina T.R., Lapochkina N.P., Galustyan A.N. on the prospects of using vitamins and minerals in the prevention of early pregnancy losses. Акушерство и гинекология/ Obstetrics and Gynecology. 2021; 4: 12-22. (in Russian)]. https://dx.doi.org/10.18565/aig.2021.4.12-22.
Коденцова В.М., Рисник Д.В. Мультимикронутриентные комплексы в питании беременных женщин: критический разбор результатов исследований. Медицинский алфавит. 2021; 21: 68-74. [Kodentsova V.M., Risnik D.V. Multimicronutrient supplements in nutrition of pregnant women: critical analysis of research results. Medical Alphabet. 2021; 21: 68-74. (in Russian)]. https://dx.doi.org/10.33667/2078-5631-2021-21-68-74.
Макарова С.Г., Коденцова В.М., Ладодо О.Б., Продеус А.П., Басаргина М.А., Буцкая Т.В., Ясаков Д.С. Микронутриентный статус беременной женщины: риски, связанные с дефицитом и методы коррекции. Акушерство и гинекология. 2020; 5: 156-64. [Makarova S.G., Kodentsova V.M., Ladodo O.B., Prodeus A.P., Basargina M.A., Butskaya T.V., Yasakov D.S. Micronutrient status of a pregnant woman: deficiency-associated risks and correction methods Акушерство и гинекология. 2020; 5: 156-64. (in Russian)]. https://dx.doi.org/10.18565/aig.2020.5.156-64.
Громова О.А., Торшин И.Ю., Тетруашвили Н.К., Серов В.Н., Коденцова В.М., Малявская С.И., Гришина Т.Р., Громов А.Н., Калачева А.Г., Керимкулова Н.В., Лиманова О.А., Мозговая Е.А., Гришина Т.Р., Громов А.Н., Калачева А.Г., Керимкулова Н.В., Лиманова О.А., Грачева О.Н. Интеллектуальный анализ данных по течению и исходу беременности: роли различных витаминно-минеральных комплексов. Медицинский алфавит. 2018; 1(6): 10-23. [Gromova O.A., Torshin I.Yu., Gromov A.N., Grishina T.R., Kalachyova A.G., Kerimkulova N.V., Limanova O.A., Malyavskaya S.I., Tetruashvili N.K., Serov V.N., Kodentsova V.M., Mozgovaya E.A., Grachyova O.N. Data mining in course and outcome of pregnancy: role of vitamin and mineral complexes. Medical Alphabet. 2018; 1(6): 10-23. (in Russian)].
Коденцова В.М. Витамины и минералы как фактор предупреждения дефектов развития плода и осложнений беременности. Медицинский совет. 2016; 9: 106-14. [Kodentsova V.M. Rationale аnd Benefits of Multivitamins Supplementation for Pregnant Women. Medical Council. 2016; 9: 106-14. (in Russian)]. https://dx.doi.org/10.21518/2079-701X-2016-9-106-114.
Бекетова Н.А., Коденцова В.М., Абрамова Т.В., Сокольников А.А., Гмошинская М.В., Кошелева О.В., Переверзева О.Г., Вржесинская О.А., Карагулян О.Р. Витаминный статус беременных женщин, проживающих в Московском регионе: влияние приема витаминно-минеральных комплексов. Фарматека. 2017; 3: 41-5. [Beketova N.A., Kodentsova V.M., Abramova T.V., Sokolnikov A.A., Gmoshinskaya M.V., Kosheleva O.V., Pereverzeva O.G., Vrzhesinskaya O.A., Karagulyan O.R. Vitamin status of pregnant women living in moscow region: the influence of vitamin-mineral complexes. Farmateka. 2017; 3: 41-5. (in Russian)].
Вржесинская О.А., Переверзева О.Г., Гмошинская М.В., Коденцова В.М., Сафронова А.И., Коростелева М.М. Алешина И.В., Фандеева Т.А. Обеспеченность водорастворимыми витаминами и состояние костной ткани у беременных женщин. Вопросы питания. 2015; 84(3): 70-6. [Vrzhesinskaya O.A., Pereverzeva O.G., Gmoshinskaya M.V., Kodentsova V.M., Safronova A.I., Korosteleva M.M., Aleshina I.V., Fandeeva T.A. Sufficiency with water-soluble vitamins and state of bone in pregnant women. Voprosy pitaniia/ Problems of Nutrition. 2015; 84 (3): 70-76. (in Russian)].
FIGO Committee Report. Good clinical practice advice: Micronutrients in the periconceptional period and pregnancy. Int. J. Gynecol. Obstet. 2019; 144: 317-21. https://dx.doi.org/10.1002/ijgo.12739.
Overb G., Rasmussen I.S., Siersma V., Andersen J.H., Kragstrup J., Wilson P. et al. Depression and anxiety symptoms in pregnant women in Denmark during COVID-19. Scand. J. Public Health. 2021; 49(7): 721-9. https://dx.doi.org/10.1177/14034948211013271.
Sinaci S., Tokalioglu E.O., Ocal D., Atalay A., Yilmaz G., Keskin H.L. et al. Does having a high-risk pregnancy influence anxiety level during the COVID-19 pandemic? Eur. J. Obstet. Gynecol. Reprod. Biol. 2020; 255: 190-6. https://dx.doi.org/10.1016/j.ejogrb.2020.10.055.
Craig F., Gioia M.C., Muggeo V., Cajiao J., Aloi A., Martino I. et al. Effects of maternal psychological distress and perception of COVID-19 on prenatal attachment in a large sample of Italian pregnant women. J. Affect. Disord. 2021; 295: 665-72. https://dx.doi.org/10.1016/j.jad.2021.08.102.
Comerford K.B. Recent developments in multivitamin/mineral research. Adv. Nutr. 2013; 4(6): 644-56. https://dx.doi.org/10.3945/an.113.004523.
Richardson D.P., Lovegrove J.A. Nutritional status of micronutrients as a possible and modifiable risk factor for COVID-19: a UK perspective. Br. J. Nutr. 2021; 125(6): 678-84. 10.1017/S000711452000330X.
de Souza Monnerat J.A., Ribeiro de Souza P., da Fonseca Cardoso L.M., Mattos J.D., de Souza Rocha G., Medeiros R.F. Micronutrients and bioactive compounds in the immunological pathways related to SARS-CoV-2 (adults and elderly). Eur. J. Nutr. 2021; 60(2): 559-79. https://dx.doi.org/10.1007/s00394-020-02410-1.
Junaid K., Ejaz H., Abdalla A.E., Abosalif K.O., Ullah M.I., Yasmeen H. et al. Effective immune functions of micronutrients against SARS-CoV-2. Nutrients. 2020; 12(10): 2992. https://dx.doi.org/10.3390/nu12102992.
Mukattash T.L., Alkhalidy H., Alzu'bi B., Abu-Farha R., Itani R., Karout S. et al. Dietary supplements intake during the second wave of COVID-19 pandemic: A multinational Middle Eastern study. Eur. J. Integr. Med. 2022; 49: https://dx.doi.org/ 102102. 10.1016/j.eujim.2022.102102.
Puścion-Jakubik A., Bielecka J., Grabia M., Mielech A., Markiewicz-Żukowska R., Mielcarek K. et al. Consumption of food supplements during the three COVID-19 waves in Poland – focus on zinc and vitamin D. Nutrients. 2021; 13(10): 3361. https://dx.doi.org/ 10.3390/nu13103361.
Gryszczyńska B., Budzyń M., Grupińska J., Kasprzak M. P., Gryszczyńska A. Nutritional behaviors, vitamin supplementation and physical activity among Polish adults during the COVID-19 pandemic. Nutrients. 2022; 14(2): 331. https://dx.doi.org/10.3390/nu14020331.
Сергеева Н.М. О структурных преобразованиях на рынке биологически активных добавок РФ в период пандемии коронавируса. Азимут научных исследований: экономика и управление. 2021; 10(2): 289-92. [Sergeeva N.M. On structural transformations in the market of dietary supplements in the Russian Federation during the coronavirus pandemic. Research Azimuth: Economics and Management. 2021; 10(2): 289-92. (in Russian)]. https://dx.doi.org/10.26140/anie-2021-1002-0059.
Квачахия Л.Л. Тенденции развития рынка БАД в России в условиях коронавируса. Азимут научных исследований: экономика и управление. 2021; 10(3): 165-8. [Kvachakhia L.L. Trends in the development of the dietary supplement market in Russia in the context of coronavirus. Azimuth of scientific research: economics and management. 2021; 10(3): 165-8. (in Russian)].
Akhtar S., Das J.K., Ismail T., Wahid M., Saeed W., Bhutta Z.A. Nutritional perspectives for the prevention and mitigation of COVID-19. Nutr. Rev. 2021; 79(3): 289-300. https://dx.doi.org/10.1093/nutrit/nuaa063.
Pisoschi A.M., Pop A., Iordache F., Stanca L., Geicu O. I., Bilteanu L., Serban A.I. Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy. Eur. J. Med. Chem. 2022; 232: 114175. https://dx.doi.org/10.1016/j.ejmech.2022.114175.
Lotfi F., Akbarzadeh-Khiavi M., Lotfi Z., Rahbarnia L., Safary A., Zarredar H. et al. Baghbanzadeh, A., Naghili. B., Baradaran B. Micronutrient therapy and effective immune response: a promising approach for management of COVID-19. Infection. 2021: 49(6): 1133-47. https://dx.doi.org/10.1007/s15010-021-01644-3.
Лобыкина Е.Н. К вопросу об использовании биологически активных добавок к пище во врачебной практике. Вопросы диетологии. 2017; 7(3): 33-43. [Lobykina E.N. To the question of the use of biologically active food supplements in medical practice. Voprosy diyetologii/ Issues of dietetics. 2017; 7(3): 33-43. (in Russian)]. https://dx.doi.org/10.20953/2224-5448-2017-3-33-43.
Коденцова В.М., Рисник Д.В. Витаминно-минеральные комплексы: БАД или лекарства? Трудный пациент. 2021; 19(5): 15-21. [Kodentsova V.M., Risnik D.V. Multivitamin and mineral complexes: dietary supplements or medications? Trudnyj Pacient/Difficult Patient. 2021; 19(5): 15-21. (in Russian)]. https://dx.doi.org/10.224412/2074-1005-2021-5-15-2.

Received 25.02.2022

Accepted 24.03.2022

Vera M. Kodentsova, Dr. Dio. Sci., Professor, Chief Researcher at the Laboratory of Vitamins and Minerals, Federal Research Centre of Nutrition and Biotechnology, +7(495)698-53-30, +7(985)124-74-29, kodentsova@ion.ru, https://orcid.org/0000-0002-5288-1132, 109240, Russia, Moscow, Ustyinskiy proezd, 2/14.
Dmitry V. Risnik, PhD (Bio), Leading Researcher, Faculty of Biology, Lomonosov Moscow State University, +7(926)759-31-61, biant3@mail.ru,
https://orcid.org/0000-0002-3389-8115, 119234, Russia, Moscow, Leninskie Gory, 1-1.
Stanislav V. Pavlovich, PhD, Associate Professor, Scientific Secretary, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, +7(495)438-52-25, s_pavlovich@oparina4.ru, https://orcid.org/0000-0002-1313-7079, 117997, Russia, Moscow, Academician Oparin str., 4.
Vladimir A. Klimov, PhD, Head of the Service for the Organization of Medical Care and Information Service, Academician V.I. Kulakov National Medical Research Center
for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, va_klimov@oparina4.ru, https://orcid.org/ 0000-0002-4699-7614,
117997, Russia, Moscow, Academician Oparin str., 4.
Olga B. Ladodo, PhD, Head of the National Coordinating Center for Breastfeeding Support, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, +7(925)508-55-02, o_ladodo@oparina4.ru, https://orcid.org/0000-0002-4720-7231,
117997, Russia, Moscow, Academician Oparin str., 4.

Authors' contributions: Kodentsova V.M., Ladodo O.B. – concept and design of the investigation; Kodentsova V.M., Risnik D.V. – material collection and processing; Kodentsova V.M. – writing the text; Risnik D.V. – preparation of figures, creation of the table, preparation of a list of references; Ladodo O.B., Klimov V.A., Pavlovich S.V. – editing.
Conflicts of interest: The authors declare that there are no conflicts of interest.
Funding: The article was prepared within the framework of the state assignment on the topic No. 0410-2022-0002 “The development of differentiated recommendations for optimizing the nutrition of the population using regional biological resources and the creation of innovative digital technologies for specialized food products to prevent obesity and socially significant diseases”.
For citation: Kodentsova V.M., Risnik D.V., Pavlovich S.V., Klimov V.A., Ladodo O.B.
The abilities of vitamin and mineral supplements during the COVID-19 pandemic.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2022; 5: 43-52 (in Russian)
https://dx.doi.org/10.18565/aig.2022.5.43-52

The abilities of vitamin and mineral supplements during the COVID-19 pandemic

Kodentsova V.M., Risnik D.V., Pavlovich S.V., Klimov V.A., Ladodo O.B.

Keywords

References

About the Authors

Similar Articles