HPV-associated diseases: questions and answers

Kostava M.N.

Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia
Human papillomavirus (HPV) is the most common sexually transmitted infection. Two thirds of women become infected within 2 years after the onset of sexual activity. HPV genetic material can be found in almost all forms of cervical cancer and in some cancers of the anogenital region and oropharynx. The problem of HPV-associated diseases and cervical cancer is very serious, due to the fact that the prevalence of HPV is extremely high. The total number of people infected with HPV is approaching 700 million. According to the available statistical data, favourable outcome of HPV-associated diseases can be observed mainly in young women, however, the diseases may run for quite a long period of time. Taking into account the characteristics of HPV-associated diseases, it is possible to use immunomodulatory drugs, such as inosine pranobex (Groprinosin). It can contribute to the activation of local immunity, as well as the creation of more favorable conditions for surgical treatment and prevention of relapses.

Keywords

papillomavirus infection (PVI)
HPV
inosine pranobex
Groprinosin

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Received 10.10.2021

Accepted 10.11.2021

About the Authors

Marina N. Kostava , Ph.D., doctor of the scientific and polyclinic department, V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, secretary of the international public organization "Association for Cervical Pathology and Colposcopy".

Conflicts of interest: The author declares that there are no competing interests.
Funding: The study was performed without any financial support.
For citation: Kostava M.N. HPV-associated diseases: questions and answers.
Akusherstvo i Ginekologiya / Obstetrics and Gynecology. 2021; 11: 267-276 (in Russian)
https://dx.doi.org/10.18565/aig.2021.11.267-276

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