Successful delivery of a twin pregnancy in a patient with a rare genital malformation
Sukhanov A.A., Obryadov M.A., Dikke G.B., Kukarskaya I.I.
Background: Pregnancy in patients with uterine malformations such as complete intrauterine septum with duplicated cervix is rare and it is associated with the risk of complications. There is no unified guidance on the management and delivery.
Case report: A 35-year-old female patient with a complete intrauterine septum and duplicated cervix had her third twin pregnancy (in each uterus) with the help of assisted reproductive technologies (ART). The woman had a previous history of two miscarriages and secondary infertility. There was a threat of miscarriage at 14–15 weeks gestation, the pregnancy was prolonged to 34 weeks 4 days. A cesarean section was performed after premature rupture of the membranes. The woman gave birth to live premature babies: a female with a weight of 2172 g and height of 46 cm long, and a male with a weight of 2416 g and height of 50 cm; they were both in a satisfactory condition.
Conclusion: This is an extremely rare clinical case when a woman with a complete intrauterine septum, duplicated cervix, and a history of habitual miscarriage becomes pregnant with twins after ART. The favorable outcome of this pregnancy is determined by accurate interpretation of the ultrasound image and the correct sequence of actions during pregnancy for prolongation and delivery.
Authors’ contributions: Sukhanov A.A., Obryadov M.A. – the analysis of the obtained data, review of publications on the issue, writing the first version of the text of the article; Dikke G.B. – the analysis of literary sources, editing the first version of the article; Kukarskaya I.I. – developing the design of the study, organization of the research, guidance during the study.
Conflicts of interest: The authors declare no possible conflicts of interest.
Funding: The study was not sponsored.
Ethical Approval: The study was reviewed and approved by the Research Ethics Committee of the Perinatal Medical Center, Tyumen, Russia.
Patient Consent for Publication: The patient provided informed consent for the publication of her data and associated images.
For citation: Sukhanov A.A., Obryadov M.A., Dikke G.B., Kukarskaya I.I. Successful delivery of a twin pregnancy in a patient with a rare genital malformation. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2023; (11): 205-210 (in Russian)
https://dx.doi.org/10.18565/aig.2023.246
Keywords
genital malformation
complete intrauterine septum
duplicated cervix
assisted reproductive technologies
twins
habitual miscarriage
prolongation of pregnancy
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Received 24.10.2023
Accepted 10.11.2023
About the Authors
Anton A. Sukhanov, PhD, Head of the Department of Gynecology, Perinatal Center, 1 Daudelnaya str., Tyumen, 625002, Russia; Associate Professor, Departmentof Obstetrics and Gynecology, Institute of Maternity and Childhood, Tyumen State Medical University, Ministry of Health of Russia, 54, Odesskaya str., Tyumen,
625023, Russia, such-anton@yandex.ru, https://orcid.org/0000-0001-9092-9136
Mikhail A. Obryadov, student of the Pediatric Faculty, Tyumen State Medical University, Ministry of Health of Russia, 54, Odesskaya str., Tyumen,
625023, Russia, mikhail-obryadov@mail.ru, https://orcid.org/0009-0009-8518-1800
Galina B. Dikke, Dr. Med. Sci., Professor, Department of Obstetrics and Gynecology with a Course of Reproductive Medicine, F.I. Inozemtsev Academy of Medical Education, 22 liter M, Moskovsky Prospect, St. Petersburg, 190013, Russia, galadikke@yandex.ru, https://orcid.org/0000-0001-9524-8962
Irina I. Kukarskaya, Dr. Med. Sci., Associate Professor, Head of the Department of Obstetrics, Gynecology and Perinatology, Institute of Maternity and Childhood, Tyumen State Medical University, Ministry of Health of Russia, 54, Odesskaya str., Tyumen, 625023, Russia; Chief Physician, Perinatal Center, 1 Daudelnaya str., Tyumen,
625002, Russia; Chief Specialist in Obstetrics and Gynecology, Department of Health of the Tyumen Region, https://orcid.org/0000-0002-8275-3553
Corresponding author: Anton A. Sukhanov, such-anton@yandex.ru
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