The course of pregnancy and labor in patients who previously had HPV-related disease

Kachalina T.S., Kachalina O.V., Vakhabova G.A.

Volga Regional Research Medical University, Ministry of Health of Russia, Nizhny Novgorod
Objective. To analyze the course of pregnancy, by evaluating the cervical status, and labor in patients previously treated for different types of HPV-related disease.
Subjects and methods. The course of pregnancy and labor was analyzed in 128 patients who had a history of HPV-related cervical disease, by using various therapeutic techniques.
Results. Isthmicocervical insufficiency established by cervical echographic parameters occurs 3.9 times more frequently (p < 0.05) after cervical surgery. The most pronounced cervical shortening in HPV-related epithelial disease is observed at 16–18 weeks’ gestation.
Conclusion. When the symptoms of threatened miscarriage appear in patients, it is necessary to perform combination treatment aimed at preserving pregnancy: correction of vaginal microbiocenosis, use of МсDonald’s cerclage, insertion of Doctor Arabin’s pessary, and administration of micronized progesterone. The used therapy allows pregnancy to be prolonged to the delivery date.

Keywords

HPV-related cervical disease
pregnancy
cervical status

References

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Received 08.12.2017

Accepted 22.12.2017

About the Authors

Kachalina, Tatyana S., Doctor of Medical Sciences, Professor of the Department of Obstetrics and Gynecology, Privolzhsky Research Medical University,
Ministry of Health of Russia. 603005, Russia, Nizhny Novgorod, pl. Minin and Pozharsky 10/1. Tel.: +79519065830. E-mail: yander24@bk.ru
Kachalina, Olga V., Doctor of Medical Sciences, Associate Professor of the Department of Obstetrics and Gynecology FDPO, Privolzhsky Research Medical University, Ministry of Health of Russia. 603005, Russia, Nizhny Novgorod, pl. Minin and Pozharsky 10/1. Tel.: +79519043406. E-mail: yander24@bk.ru
Vakhabova, Gyular A., graduate student of the Department of Obstetrics and Gynecology, Privolzhsky Research Medical University, Ministry of Health of Russia.
603005, Russia, Nizhny Novgorod, pl. Minin and Pozharsky 10/1. Tel.: +79308036838. E-mail: g.mikailova90@mail.ru

For citations: Kachalina T.S., Kachalina O.V., Vakhabova G.A. The course of pregnancy and labor in patients who previously had HPV-related disease. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (7): 62-6. (in Russian)
https://dx.doi.org/10.18565/aig.2018.7.62-66

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