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Obstetrics and Gynegology2021№9
Current understanding of the relationship...

Current understanding of the relationship between gut and vaginal microbiotas

DOI
https://dx.doi.org/10.18565/aig.2021.9.5-11

Nikolaeva A.V., Kozlova A.A., Baranov I.I., Priputnevich T.V.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia
The paper reviews publications devoted to cross-sectional studies of the composition of vaginal and gut microbiotas in order to assess the relationship between impaired intestinal microbiocenosis and dysbiotic processes in vaginal microbiocenosis. An analysis of the literature has shown that the change in the number of certain types of microorganisms in a particular biotope or the identification of species that are not peculiar to this habitat serves as a signal for adaptive or irreversible changes in the appropriate component of the microecosystem. These changes are known to be interrelated and occur simultaneously in several biotopes. Vaginal dysbiosis can result in a cascade of processes that disrupt balance in the female reproductive tract, causing various infectious and inflammatory processes. In this connection, gut and vaginal microbiotas as indicators of female reproductive health deserve the special attention of obstetricians and gynecologists today. A number of recent studies have identified a correlation between microbial communities in pregnant women and women whose pregnancy was complicated. Both the vaginal and gut microbiotas contribute to mother-to-infant Bifidobacterium transmission, and establishing the fact that the vaginal and gut bacteria represent the same population is an important step for future studies of maternal and neonatal health.
Conclusion: Data on the intestinal microflora serve as informative indicators of a woman's health, and the substantial changes in the composition of the intestinal microbiocenosis require adequate correction. The expediency of conducting studies in this area is confirmed.

Keywords

microbiota
vaginal microbiome
gut microbiota
opportunistic microorganisms
biotope
dysbiotic disorders
microbial colonization
Full text (in Russian)

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Received 26.03.2021

Accepted 05.05.2021

About the Authors

Anastasia V. Nikolaeva, Ph.D., Chief physician, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology,
Ministry of Healthcare of Russian Federation, +7(916)653-43-09, a_nikolaeva@oparina4.ru, 117997, Russia, Moscow, Ac. Oparina str., 4.
Anastasia A. Kozlova, graduate student of 1st obstetric physiological department, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology
and Perinatology, Ministry of Healthcare of Russian Federation, +7(926)656-19-49, aakozlova.box@gmail.com, 117997, Russia, Moscow, Ac. Oparina str., 4.
Igor I. Baranov, Dr. Med. Sci., Professor, Head of the Department of Scientific and Educational Programs, Academician V.I. Kulakov National Medical Research Center
for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation, i_baranov@oparina4.ru, https://orcid.org/0000-0002-9813-2823, 117997, Russia, Moscow, Ac. Oparina str., 4.
Tatiana V. Priputnevich, Head of the Department of Microbiology, Clinical Pharmacology and Epidemiology, Academician V.I. Kulakov National Medical Research Center
for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation, +7(910)414-56-16, priput1@gmail.com, 117997, Russia, Moscow,
Ac. Oparina str., 4.

Authors' contributions: Kozlova A.A., Nikolaeva A.V. – choosing a research topic; Kozlova A.A., Nikolaeva A.V., Priputnevich T.V. – search for literary data; Kozlova A.A. – writing the manuscript of the article; Priputnevich T.V., Baranov I.I. – writing and editing the article.
Conflicts of interest: The authors declare that there are no conflicts of interest.
Funding: There has been no funding for the preparation of the article for publication.

For citation: Nikolaeva A.V., Kozlova A.A., Baranov I.I., Priputnevich T.V. Current understanding of the relationship between gut and vaginal microbiotas.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2021; 9: 5-11 (in Russian)
https://dx.doi.org/10.18565/aig.2021.9.5-11

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