Obstructive sleep apnea syndrome during pregnancy

Solomakha A.Yu., Petrova N.A., Bezhenar V.F., Ivanov D.О.

1) Saint Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, Saint Petersburg, Russia; 2) V.A. Almazov National Medical Research Center, Ministry of Health of the Russian Federation, Saint Petersburg, Russia; 3) Academician I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of the Russian Federation, Saint Petersburg, Russia
The review presents up-to-date data on the current state of the problem of sleep-related breathing disorders in pregnant women.
Obstructive sleep apnea syndrome (OSAS) is a common, but often unrecognized condition that has serious negative health outcomes for a pregnant woman and her future baby. Recently, this problem has been actively studied in our and foreign countries. Over the past decade, there has been a lot of accumulated clinical data on the predisposition of women during pregnancy to the development of OSAS due to physiological, hormonal, and endocrine changes during this period. In the article, the authors have attempted to reveal the mechanisms and consequences of this disease not only for the pregnant woman, but also for her fetus. To develop appropriate prevention and treatment guidelines, it is necessary to identify the relationship between the presence of OSAS in a pregnant woman, the pathological course of pregnancy, and the neonatal status. Whether there is a link between snoring during pregnancy and adverse fetal outcomes is considered. The article also discusses the possibility of using non-invasive ventilation and its impact on the course of pregnancy and concomitant diseases in women with OSAS.
Conclusion. Currently, no special studies aimed at elaborating algorithms for the management of such patients have been conducted. The early diagnosis and timely treatment of OSAS in pregnant women will improve the course and prognosis of pregnancy and lower the risk of adverse effects of intrauterine factors (hypoxia) on the fetus, which will be able to avoid premature birth and cesarean section and to prevent diseases of the cardiovascular and endocrine systems.

Keywords

pregnancy
obstructive sleep apnea syndrome

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Received 11.09.2020

Accepted 14.12.2020

About the Authors

Anna Yu. Solomakha, MD, Department of Propedeutics of Childhood Diseases with a Course of General Child Care, St. Petersburg State Pediatric Medical University, Ministry of Health of Russia, Saint Petersburg, Russia. Tel.: +7(911)114-28-92. E-mail: anka.solomaha@yandex.ru. ORCID: 0000-0003-4461-4322.
194100, Russia, Saint Petersburg, Litovskaya str., 2.
Natalia A. Petrova, MD, PhD, Head of Physiology and Pathology of Newborns Laboratory, V.A. Almazov National Medical Research Center, Saint Petersburg, Russia.
Tel.: +7(911)009-08-08. Е-mail: natalja5@yandex.ru. ORCID: 0000-0002—0850. 197341, Russia, St. Petersburg, Akkuratova str., 2.
Vitaly F. Bezhenar, MD, PhD, Dr. Med. Sci., Professor, Head of the Department of Obstetrics, Gynecology and Neonatology, Head of the Clinic of Obstetrics and Gynecology, Academician I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia; Chief obstetrician-gynecologist of the Health Committee
of the Government of Saint-Petersburg, St. Petersburg, Russia. Tel.: +7(812)429-03-40. E-mail: bez-vitaly@yandex.ru. ORCID: 0000-0002-7807-4929.
197022, Russia, St. Petersburg, Lev Tolstoy str., 6-8.
Dmitry O. Ivanov, MD, PhD, Dr. Med. Sci., Professor, Rector, St. Petersburg State Pediatric Medical University, Ministry of Health of Russia, St. Petersburg, Russia;
Сhief Neonatologist of Ministry of Health of Russia. Теl.: +7(911)542-39-83. E-mail: spb@gpmu.org. ORCID: 0000-0002-0060-4168.
194100, Russia, Saint Petersburg, Litovskaya str., 2.

For citation: Solomakha A.Yu., Petrova N.A., Bezhenar V.F., Ivanov D.О. Obstructive sleep apnea syndrome during pregnancy.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2021; 2: 27-31 (in Russian)
https://dx.doi.org/10.18565/aig.2021.2.27-31

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