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Obstetrics and Gynegology2024№4
The role of integral methods...

The role of integral methods for assessing the hemostatic system in the diagnosis and transfusion tactics in postpartum hemorrhage

DOI
https://dx.doi.org/10.18565/aig.2024.90

Dikov A.V., Beznoshchenko O.S., Yusupova A.A., Pyregov A.V.

1) Academician V.I. Kulakov National Medical Research Centre for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia; 2) Moscow Regional Perinatal Center, Balashikha, Russia

Postpartum hemorrhage (PPH) is the leading cause of maternal mortality in the world. Timely detection of hemostatic disorders is crucial for the prevention of massive PPH. Numerous data confirm the high clinical significance of the point of care (POC) testing in PPH. Rapid assessment of the state of the hemostatic system using thromboelastography (TEG) and thromboelastometry (TEM) makes it possible to identify the cause of coagulopathy; transfusion tactics in PPH can be justified using algorithms based on parameters of TEG and TEM. The use of integral methods (TEG, TEM) in patients with postpartum hemorrhage led to improved outcomes, including intra- and postoperative complications, reduced mortality, and improved patients’ safety. The introduction of the TEG and TEM methods into routine practice requires appropriate technical equipment and an interdisciplinary approach.
Conclusion: The study presents the summary and analysis of information on the role of integral methods (TEG, TEM) for the diagnosis of hemostatic disorders in patients with PPH. There is a description of the POC algorithm which is relevant from the clinical point of view for finding the causes of massive hemorrhage and targeted therapy.

Authors’ contributions: Dikov A.V., Beznoshchenko O.S., Yusupova A.A. – collection and analysis of literary data, writing the article; Pyregov A.V. – final approval of the publication.
Conflicts of interest: The authors declare no possible conflicts of interest.
Funding: The study was conducted without sponsorship.
For citation: Dikov A.V., Beznoshchenko O.S., Yusupova A.A., Pyregov A.V. The role of integral methods for assessing 
the hemostatic system in the diagnosis and transfusion tactics in postpartum hemorrhage.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2024; (4): 16-23 (in Russian)
https://dx.doi.org/10.18565/aig.2024.90

Keywords

postpartum hemorrhage
integral methods
thromboelastometry
thromboelastography
targeted therapy
Full text (in Russian)

References

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Received 13.02.2024

Accepted 16.04.2024

About the Authors

Alexey V. Dikov, anesthesiologist-resuscitator at the Institute of Anesthesiology-Resuscitation and Transfusiology, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, +7(495)438-77-77, dikov.08@gmail.com
Olga S. Beznoshchenko, Ph.D. (Med), Doctor at the Clinical Laboratory Diagnostics, Institute of Anesthesiology-Resuscitation and Transfusiology, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, 7(495)438–77–77.
Amina I. Yusupova, resident of the Institute of Anesthesiology-Resuscitation and Transfusiology, Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4 +7(495)438–77–77, yusupov8991@yandex.ru
Aleksey V. Pyregov, Dr. Med. Sci., Professor, Deputy Chief Physician for Anesthesiology and Resuscitation, Moscow Regional Perinatal Center; Chief Non-staff Specialist of the Ministry of Health of the Moscow Region for Anesthesiology and Resuscitation in Obstetrics and Gynecology, pyregov@mail.ru
Corresponding author: Alexey Pyregov, pyregov@mail.ru

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