Rehabilitation of vulvar cancer patients

Solopova A.G., Moskvicheva V.S., Blbulyan T.A., Makatsariya A.D., Dudina A.N., Meng M.

1) I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Moscow, Russia; 2) Mkhitar Heratsi Yerevan State Medical University, Yerevan, Armenia
Rehabilitation of vulvar cancer patients is a continuous process that starts at diagnosis and continues throughout life. A multidisciplinary rehabilitation care approach involves the participation of a whole health team of physicians and nurses in various areas. For the early detection of relapses, diagnostic monitoring (tumor markers, ultrasonography, magnetic resonance imaging, positron emission tomography/computed tomography) is indicated for all patients. Particular attention should be paid to the quality of life in women, by restoring the physiological functions impaired due to the illness and/or treatment, by correcting the mental status and sexual dysfunction.

Keywords

vulvar cancer
rehabilitation
quality of life
sexual dysfunction
pre-rehabilitation

References

  1. Dellinger T.H., Hakin A.A., Lee S.J., Wakabayashi M.T., Morgan R.J., Han E.S. Surgical management of vulvar cancer. J. Natl. Compr. Canc. Netw. 2017; 15(1): 121–8. https://dx.doi.org/10.6004/jnccn.2017.0009
  2. Woelber L., Trillsch F., Kock L., Grimm D., Petersen C., Choschzick M. et al. Management of patients with vulvar cancer: a perspective review according to tumour. Ther. Adv. Med. Oncol. 2013; 5(3): 183–92. https://dx.doi.org/10.1177/1758834012471699.
  3. Mitra S., Sharma M.K., Kaur I., Khurana R., Modi K.B., Narang R. et al. Vulvar carcinoma: dilemma, debates, and decisions. Cancer Manag. Res. 2018; 10: 61–8. https://dx.doi.org/10.2147/CMAR.S143316.
  4. Прилепская В.Н., Зардиашвили М.Д., Хлебкова Ю.С., Некрасова М.Е. Вакцинация против ВПЧ-ассоциированных заболеваний и рака шейки матки. Теоретические и практические аспекты. Медицинский совет. 2016; 12: 120–5. [Prilepskaya V.N., Zardiashvili M.D., Khlebkova Y.S., Nekrasova M.E. Vaccination against HPV-associated diseases and cervical cancer: theoretical and practical aspects. Meditsinskiy sovet/ Medical Council. 2916; (12): 120–5. (in Russian)].
  5. Шалбаева Р.Ш., Кайрбаев М.Р., Макимбетов Э.К. Возраст как фактор риска при раке вульвы. Вестник Тамбовского университета. Серия: Естественные и технические науки. 2017; 22(2): 247–52. [Shalbaeva R.S., Kayrbaev M.R., Makimbetov E.K. Age as a risk factor for cancer of the vulva. Vestnik Tambovskogo universiteta. Seriya: Estestvennye i tekhnicheskie nauki/ Tambov University Reports. Series: Natural and Technical Sciences. 2017; 22(2): 247–52. (in Russian)]
  6. Пушкарёв В.А., Мазитов И.М., Хуснутдинов Ш.М., Голов Е.К. Анализ клинико-патологических особенностей рака вульвы. Медицинский вестник Башкортостана. 2014; 9(3): 50–4. [Pushkarev V.A., Mazitov I.M., Khusnutdinov Sh.M., Golov E.K. Analysis of clinical and pathological features of vulvar cancer. Meditsinskiy vestnik Bashkortostana/Bashkortostan Medical Journal. 2014; 9(3): 50–4. (in Russian)]
  7. Suk R., Mahale P., Sonawane K., Sikora A.G., Chhatwal J., Schmeler K.M. et al. Trends in risks for second primary cancers associated with index human papillomavirus-associated cancers. JAMA Netw. Open. 2018; 1(5): e181999. https://dx.doi.org/10.1001/jamanetworkopen.2018.1999
  8. Rottenstreich M., Armon S., Beller U., Rosengarten O., Vernea F., Reichman O. Recurrence of endometrial carcinoma presenting as vulvar lesions. Int. J. Gynaecol. Obstet. 2019; 145(1): 123–4. https://dx.doi.org/10.1002/ijgo.12762
  9. Alkatout I., Schubert M., Garbrecht N., Weigel M.T., Jonat W., Mundhenke Ch., Gunther V. Vulvar cancer: epidemiology, clinical presentation, and management options. Int. J. Womens Health. 2015; 7: 305–13. https://dx.doi.org/10.2147/IJWH.S68979
  10. Солопова А.Г., Москвичёва В.С., Блбулян Т.А., Макацария А.Д. Восстановление сексуальной функции у пациенток с краурозом вульвы. Акушерство, гинекология и репродукция. 2019; 13(1): 63–9. [Solopova A.G., Moskvichyova V.S., Blbulyan T.A., Makatsariya A.D.Restoration of sexual function in patients with kraurosis vulvae. Akusherstvo, ginekologiya i reproduktsiya/Obstetrics, Gynecology and Reproduction. 2019; 13(1): 63–9. (in Russian)]
  11. Роик Е.Е., Баранов А.Н., Трещева Н.Д. Эпидемиологические особенности папилломавирусной инфекции. Экология человека. 2015; 5: 21–6. [Roik E.E., Baranov A.N., Treshcheva N.D. Epidemiological features of human papilloma viral infection. Ekologiya cheloveka/Human Ecology journal. 2015; (5); 21–6. (in Russian)]
  12. Бабаева Н.А., Ашрафян Л.А., Антонова И.Б., Алешикова О.И., Ивашина С.В., Баранов И.И. Современный взгляд на этиологию и патогенез предраковых заболеваний и рака вульвы. Акушерство и гинекология: новости, мнения, обучение. 2019; 7(1): 31–8. [Babaeva N.A., Ashrafyan L.A., Antonova I.B., Aleshikova O.I., Ivashina S.V., Baranov I.I. Modern view on etiology and pathogenesis of pre-malignant conditions and vulvar cancer. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie. 2019; 7(1): 31–8. (in Russian)]
  13. Брико Н.И., Лопухов П.Д., Каприн А.Д., Новикова Е.Г., Трушина О.И., Халдин А.А., Жукова О.В., Исаева Д.Р., Скворцова А.И. ВПЧ-ассоциированные заболевания в структуре онкогинекологической патологии и инфекций, передаваемых половым путём, в Москве и в России. Инфекция и иммунитет. 2017; 7(4): 359–67. [Briko N.I., Lopukhov P.D., Kaprin A.D., Novikova E.G.,Trushina O.I., Khaldin A.A., Zhukova O.V., Skvortsova A.I. HPV-associated diseases in the structure of female reproductive tract tumors and sexually transmitted infections in Moscow and Russia. Infektsiya i immunitet/Russian Journal of Infection and Immunity. 2017; 7(4): 359–67. (in Russian)].
  14. Ledford L.R.C., Lockwood S. Scope and epidemiology of gynecologic cancers: an overview. Semin. Oncol. Nurs. 2019; 35(2): 147–50. https://dx.doi.org/10.1016/j.soncn.2019.03.002
  15. Teoh D., Shaikh R., Vogel R.I., Zoellner T., Carson L., Kulasingam S., Lou E. A cross-sectional review of cervical cancer messages on twitter during cervical cancer awareness month. J. Low. Genit. Tract Dis. 2018; 22(1): 8–12. https://dx.doi.org/10.1097/LGT.0000000000000363.
  16. Allen J. The clinical nurse specialist in gynaecological oncology-the role in vulvar cancer. Best Pract. Res. Clin. Obstet. Gynaecol. 2003; 17(4): 591–607. https://dx.doi.org/10.1016/s1521-6934(03)00041-5.
  17. Bakker R.M., ter Kuile M.M., Vermeer W.M., Nout R.A., Mens J.W., van Doorn L.C. et al. Sexual rehabilitation after pelvic radiotherapy and vaginal dilator use: consensus using the Delphi method. Int. J. Gynecol. Cancer. 2014; 24(8): 1499–506. https://dx.doi.org/10.1097/IGC.0000000000000253.
  18. Hammer K., Mogensen O., Hall E.O. Hope as experienced in women newly diagnosed with gynaecological cancer. Eur. J. Oncol. Nurs. 2009; 13(4): 274–9. https://dx.doi.org/10.1016/j.ejon.2009.02.004.
  19. Huffman L.B., Hartenbach E.M., Carter J., Rash J.K., Kushner D.M. Maintaining sexual health throughout gynecologic cancer survivorship: a comprehensive review and clinical guide. Gynecol. Oncol. 2016; 140(2): 359–68. https://dx.doi.org/10.1016/j.ygyno.2015.11.010
  20. Aerts L., Enzlin P., Verhaeghe J., Vergote I., Amant F. Sexual and psychological functioning in women after pelvic surgery for gynaecological cancer. Eur. J. Gynaecol. Oncol. 2009; 30(6): 652–6.
  21. Саевец В.В., Важенин А.В., Чернова Л.Ф., Мухин А.А., Кравченко Г.Р., Таратонов А.В. Роды после перенесенного рака вульвы с расширенной вульвэктомией пластикой. Исследования и практика в медицине. 2018; 5(Спецвыпуск 2): 124. [Saevec V.V., Vajenin A.V., Chernova L.F., Muhin A.A., Kravchenco G.R., Taratonov A.V. Childbirth after suffered vulvar cancer with an enlarged vulvectomy with plastic. Issledovaniya i praktika v meditsine/Research’n Practical Medicine Journal. 2018; 5(Suppl. 2): 124. (in Russian)]
  22. Levin A.O., Carpenter K.M., Fowler J.M., Brothers B.M., Andersen B.L., Maxwell G.L. Sexual morbidity associated with poorer psychological adjustment among gynecological cancer survivors. Int. J. Gynecol. Cancer. 2010; 20(3): 461–70. https://dx.doi.org/10.1111/IGC.0b013e3181d24ce0.
  23. Пушкарёв В.А., Мазитов И. М. Рак вульвы. Медицинский вестник Башкортостана. 2013; 8(1): 123–32. [Pushkarev V.A., Mazitov I.M. Vuiva cancer. Meditsinskiy vestnik Bashkortostana/Bashkortostan Medical Journal. 2013; 8(1): 123–32. (in Russian)]
  24. McClurg D., Hagen S. Quality of life issues following surgery for vulvar cancer: a case report. Physiother. Res. Int. 2009; 14(3): 193–8. https://dx.doi.org/10.1002/pri.442
  25. Nigriny J.F., Wu P., Butler C.E. Perineal reconstruction with an extrapelvic vertical rectus abdominis myocutaneous flap. Int. J. Gynecol. Cancer. 2010; 20(9): 1609–12. https://dx.doi.org/10.1111/IGC.0b013e3181fc11ee
  26. Koulaxouzidis G., Penna V., Bannasch H., Neeff H.P., Manegold P., Aigner F. et al. The adipofasciocutaneous gluteal fold perforator flap a versatile alternative choice for covering perineal defects. Int. J. Colorectal Dis. 2019; 34(3): 501–11. https://dx.doi.org/10.1007/s00384-018-03222-w
  27. Confalonieri P.L., Gilardi R., Rovati L.C., Ceccherelli A., Lee J.H., Magni S., Del Bene M., Buda A. Comparison of V-Y advancement flap versus lotus petal flap for plastic reconstruction after surgery in case of vulvar malignancies: a retrospective single center experience. Ann. Plast. Surg. 2017; 79(2): 186–91. https://dx.doi.org/10.1097/SAP.0000000000001094
  28. Mercut R., Sinna R., Vaucher R., Giroux P.A., Assaf N., Lari A., Dast S. Triple flap technique for vulvar reconstruction. Ann. Chir. Plast. Esthét. 2018; 63(4): 343–8. https://dx.doi.org/10.1016/j.anplas.2018.03.007
  29. Жаров А.В. Комбинированные и реконструктивно-пластические операции у больных с рецидивами рака вульвы. Исследования и практика в медицине. 2018; 5(Cпецвыпуск 1): 35. [Zharov A.V. Combined and reconstructive-plastic surgeries in patients with recurrence of cancer of the vulva. Issledovaniya i praktika v meditsine/Research’n Practical Medicine Journal. 2018; 5(Suppl. 1): 35. (in Russian)]
  30. Черенков В.Г., Александрова И.В. Методические подходы оценки социально-психологических проблем и качества жизни больных раком вульвы, перенесших хирургическое лечение. Вестник Новгородского государственного университета им. Ярослава Мудрого. 2010; 59: 109–15. [Cherenkov V.G., Aleksandrova I.V. Metodicheskie podkhody otsenki sotsial’no-psikhologicheskikh problem i kachestva zhizni bol’nykh rakom vul’vy, perenesshikh khirurgicheskoe lechenie. Vestnik Novgorodskogo gosudarstvennogo universiteta im. Yaroslava Mudrogo. 2010; 59: 109–15. (in Russian).]
  31. Lokich E. Gynecologic cancer survivorship. Obstet Gynecol Clin. North Am. 2019; 46(1): 165–78. https://dx.doi.org/10.1016/j.ogc.2018.10.002
  32. Hay C.M., Donovan H.S., Hartnett E.G., Carter J., Roberge M.C., Campbell G.B. et al. Sexual health as part of gynecologic cancer care: what do patients want? Int. J. Gynecol. Cancer. 2018; 28(9): 1737–42. https://dx.doi.org/10.1097/IGC.0000000000001376
  33. Крикунова Л.И., Марынский Ю.С. Лучевое и химиотерапевтическое лечение рака вульвы. Практическая онкология. 2006; 7(4): 216–20. [Krikunova L.I., Marynskii Yu.S. Luchevoe i khimioterapevticheskoe lechenie raka vul’vy. Prakticheskaya onkologiya. 2006; 7(4): 216–20. (in Russian)]
  34. Carter J., Stabile C., Seidel B., Baser R.E., Goldfrank Sh., Goldfrank D.J. Vaginal and sexual health treatment strategies within a female sexual medicine program for cancer patients and survivors. J. Cancer Surviv. 2017; 11(2): 274–83. https://dx.doi.org/10.1007/s11764-016-0585-9
  35. Солопова А.Г., Табакман Ю.Ю., Идрисова Л.Э., Сдвижков А.М. Реабилитация онкогинекологических больных. Взгляд на проблему. Акушерство, гинекология и репродукция. 2015; 9(4): 46–54. https://dx.doi.org/10.17749/2070-4968.2015.9.046-054. [Solopova A.G., Tabakman Yu.Yu., Idrisova L.E., Sdvizhkov A.M. Rehabilitation of oncogynecologic patients. View of a problem. Akusherstvo, ginekologiya i reproduktsiya/Obstetrics, Gynecology and Reproduction. 2015; 9(4): 46–54. https://dx.doi.org/10.17749/2070-4968.2015.9.046-054. (in Russian)]

Received 19.11.2019

Accepted 29.11.2019

About the Authors

Antonina G. Solopova, MD, PhD, Professor, Department of Obstetrics and Gynecology of Children’s Health Institute, I.M. Sechenov First MSMU HM of RF.
Phone: +7(916)676-48-45. E-mail: antoninasolopova@yandex.ru. ORCID: https://orcid.org/0000-0002-7456-2386. Researcher ID: Q-1385-2015.
Scopus Author ID: 6505479504.
119991 Russia, Moscow ul. Trubetskaya, 8, str. 2.
Viktoriya S. Moskvichyova, Clinical Resident, Department of Sports Medicine and Medical Rehabilitation, I.M. Sechenov First MSMU HM of RF. Phone: +7 (925)129-09-22. E-mail: moskvicheva_viktoria@mail.ru. ORCID: https://orcid.org/0000-0003-4202-1144. Researcher ID: H-2410-2019. Scopus Author ID: 57201495137.
119991 Russia, Moscow ul. Trubetskaya, 8, str. 2.
Tatevik A. Blbulyan, Assistant, Department of Obstetrics and Gynecology, Yerevan SMU n.a. Mkhitar Heratsi. E-mail: tblbulyan@gmail.com.
Alexander D. Makatsariya, MD, PhD, Acad. of RAS, Professor, Head of the Department of Obstetrics and Gynecology of Children’s Health Institute, I.M. Sechenov First MSMU HM of RF. E-mail: gemostasis@mail.ru. ORCID: https://orcid.org/0000-0001-7415-4633. Researcher ID: M-5660-2016. Scopus Author ID: 6602363216.
Anastasiya N. Dudina, 5th year student, Faculty of Pediatrics, I.M. Sechenov First MSMU HM of RF. Phone: +7(915)164-97-94. E-mail: dudina97@mail.ru.
ORCID: https://orcid.org/0000-0003-3778-4067
Address: 119991 Russia, Moscow ul. Trubetskaya, 8, str. 2.
Meng Muyang, postgraduate Student, Department of Obstetrics and Gynecology of Children’s Health Institute. E-mail: mmy88888@163.com
119991 Russia, Moscow ul. Trubetskaya, 8, str. 2.

For citation: Solopova A.G., Moskvicheva V.S., Blbulyan T.A., Makatsariya A.D., Dudina A.N., Meng M. Rehabilitation of vulvar cancer patients .
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2019; 12: 188-92. (In Russian).
https://dx.doi.org/10.18565/aig.2019.12.188-192

Similar Articles

By continuing to use our site, you consent to the processing of cookies that ensure the proper functioning of the site.