Psychological aspects of termination of early-stage non-developing pregnancy: A randomized clinical trial
In the last decades various methods to terminate pregnancy have been widely introduced in the Kyrgyz Republic, but little attention has been paid to their impact on the psychological status of a woman.Karmyshev A.O., Ryskeldieva V.T.
Objective. To determine the rate of depressive disorders and to compare psychological outcomes in women before and after termination of early-stage non-developing pregnancy.
Subjects and methods. This was a non-blinded randomized cohort trial. A sample consisted of 633 women at less than 12 weeks+6 days of gestation; of these, 399 women had non-developed pregnancy. Testing was carried out using the Tsung pre-diagnosis depression scale.
Results. The pre-abortion rate of psychological disorders was 30.3%. There were 72.9% of mild depression cases in the structure of depressive disorders. The post-abortion rate of depression was increased by 6.0%. Following medical abortion with mefipristone in combination with misoprostol, the rate of mild depressive disorders (36.4%) was, with high statistical significance, greater than that with misoprostol alone (22.3%) (φemr 2.598; P < 0.01) and surgical abortion (20.2%) (φemr 2.872; P < 0.001).
Conclusion. The high level of depressive disorders in women with early pregnancy suggests that there is a need to elaborate programs for the early detection of psychological disorders and the choice of an abortion method.
Keywords
early-stage non-developing pregnancy
missed abortion
psychological disorders
medical and surgical abortion
Supplementary Materials
- Fig. 1. Study design
- Fig. 2. Frequency and structure of depressive disorders in women in early pregnancy
- Table 1. A comparative assessment of psychological status of women applied for abortion to the hospital
- Table 2. Comparative assessment of psychological disorders after abortion
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Received 15.06.2016
Accepted 02.09.2016
About the Authors
Karmyshev Azat Omorkulovich, head of the department of gynecology, National Center of Maternal and Child Care of the Kyrgyz Republic.720038, Kyrgyz Republic, Bishkek, Ahunbaeva str. 190. Tel.: +996 551 912 628. E-mail: azat.ok@rambler.ru
Ryskeldieva Victoria Turarbekovna, MD, senior researcher, deputy director of the Kyrgyz Research Center of Human Reproduction.
720028, Kyrgyz Republic, Bishkek, md. 7, 14/1. Tel.: +996 558 065 108. E-mail: vikaryskeldieva@gmail.com
For citations: Karmyshev A.O., Ryskeldieva V.T. Psychological aspects of termination of early-stage non-developing pregnancy: A randomized clinical trial.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (1): 19-23. (in Russian)
http://dx.doi.org/10.18565/aig.2017.1.19-23
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