Probiotics in the restoration of vaginal microbiocenosis
Objective. To analyze the data available in the current literature on the effect of probiotics on the efficiency of bacterial vaginosis therapy and their role in the physiology of the female reproductive system.Kira E.F.
Material and methods. The review included the data of foreign and Russian articles published in the past 10 years and found in Pubmed on this topic.
Results. The possible mechanisms for involvement of probiotics in the processes of recovery and maintenance of normal vaginal microbiocenosis were described. The antagonistic mechanisms of Lactobacilli were shown to suppress the opportunistic pathogenic microflora. The characteristics of a Lactobacillus casei rhamnosus strain (LCR35) used in obstetric/gynecologic practice were presented.
Conclusion. The use of probiotics containing the Lactobacillus casei rhamnosus strain in the treatment of patients with bacterial vaginosis substantially improves the results of therapy and contributes to the active normalization of vaginal microbiocenosis.
Keywords
probiotics
vaginal microbiocenosis
Lactobacillus casei rhamnosus
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Received 10.02.2017
Accepted 17.02.2017
About the Authors
Kira Evgeniy Fedorovich, MD, Prof., Acad. RANS, head of the Department of Women’s Diseases and Reproductive Health, N.I. PirogovNational Medical and Surgical Center. 105203, Russia, Moscow, Nizhnyaya Pervomayskaya str. 65. Tel.: +74994645654. E-mail: profkira33@gmail.com
For citations: Kira E.F. Probiotics in the restoration of vaginal microbiocenosis. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (5): 32-8. (in Russian)
http://dx.doi.org/10.18565/aig.2017.5.32-8
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