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The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
ArchiveEthical StandardsSubscription
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InstructionsInformed consent policyContract offerEASE GuidelinesICJME CriteriaWAME Recommendations on ChatGPT and Chatbots in Relation to Scholarly Publications
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Obstetrics and Gynegology2020№12
Pregnancy course, obstetric and therapeutic...

Pregnancy course, obstetric and therapeutic tactics for novel coronavirus infection (COVID­-19) in pregnant women

DOI
https://dx.doi.org/10.18565/aig.2020.12.6-13

Artymuk N.V., Belokrinitskaya T.E., Filippov O.S., Marochko K.V.

1) Kemerovo State Medical University, Ministry of Health of Russia, Kemerovo, Russia; 2) Chita State Medical Academy, Ministry of Health of Russia, Chita, Russia; 3) A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia
The novel coronavirus infection (NCI) (COVID-19) pandemic has posed real social, political and health challenges to the entire world. Many aspects of the management and course of this infection are controversial. The physiological characteristics of a pregnant woman's body place her, on the one hand, at risk for a more severe course of NCI, which has been confirmed in some studies. However, other authors point out that COVID-19 in pregnant women occurs in the same fashion or even more easily than in the general population. There are limited data on the prevalence of NCI among pregnant women in the Russian Federation. There are reports of both maternal and neonatal NCI-related deaths worldwide. There is a limited range of drugs used to treat NCI in pregnant women. Etiotropic therapy with a combination of lopinavir and ritonavir can be performed. Some publications have shown the efficacy and safety of hydroxychloroquine in patients with severe NCI. A prevailing number of recommendations indicate that vaginal delivery is preferable for pregnant women with NCI; however, most of them deliver an infant via cesarean section. Spousal presence during childbirth and the possibility of breastfeeding remain controversial: from ban (before having a negative COVID-19 test) to measures to support the women. There are no convincing data on the possibility of COVID-19 vertical transmission, but this issue and the rehabilitation of pregnant women who have experienced NCI (COVID-19) require further investigations.
Conclusion. Pregnancy and childbirth do not worsen the course of NCI (COVID-19). However, there are risks for some pregnancy complications, as well as neonatal ones, during both pregnancy and the long periods after the experienced NCI (COVID-19), especially its severe types. There are no convincing data on the possibility of COVID-19 vertical transmission, but this issue and the rehabilitation of pregnant women who have experienced NCI (COVID-19) require further investigations.

Keywords

COVID-19
coronavirus infection
pregnancy
Full text (in Russian)

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Received 24.08.2020

Accepted 02.09.2020

About the Authors

Natalya V. Artymuk, MD, PhD, Professor, Head of the G.A. Ushakova Department of Obstetrics and Gynecology, Kemerovo State Medical University, Ministry of Health
of Russia. Tel.: +7(3842)73-48-56. E-mail: artymuk@gmail.com. ORCID: 0000-0001-7014-6492. 22a Voroshilova str., Kemerovo, 650056, Russian Federation.
Tatiana E. Belokrinitskaya, MD, PhD, Professor, Head of the the Obstetrics and Gynecology Department, Chita State Medical Academy, Ministry of Health of Russia.
Tel.: +7(3022)32-30-58. E-mail: tanbell24@mail.ru. ORCID: 0000-0002-5447-4223. 39a Gorky str., Chita, 672000, Russian Federation.
Oleg S. Filippov, MD, PhD, Professor, Professor of the Department of Obstetrics and Gynecology, Moscow State Medical and Dental University named after A.I. Evdokimov, Ministry of Health of Russia; Deputy Director of the Department of Medical Assistance to Children and Obstetrics Aid of the Ministry of Health of Russia.
Tel.: +7(495)609-67-00. E-mail: filippovolsem@yandex.ru. ORCID: 0000-0003-2654-1334. 3 Rakhmanovsky str., Moscow, 127994, Russian Federation.
Kristina V. Marochko, PhD, assistant of the G.A. Ushakova Department of Obstetrics and Gynecology, Kemerovo State Medical University, Ministry of Health of Russia.
Tel.: +7(3842)73-48-56. E-mail: marochkokv@mail.ru. ORCID: 0000-0003-2832-6638. 22a Voroshilova str., Kemerovo, 650056, Russian Federation.

For citation: Artymuk N.V., Belokrinitskaya T.E., Filippov O.S., Marochko K.V. Pregnancy course, obstetric and therapeutic tactics for novel coronavirus infection (COVID-19) in pregnant women.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2020; 12: 6-13 (in Russian)
https://dx.doi.org/10.18565/aig.2020.12.6-13

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