Neoadjuvant chemotherapy and laparoscopic radical hysterectomy for locally advanced cervical cancer
Objective. To investigate the efficiency of neoadjuvant chemotherapy in combination with laparoscopic radical hysterectomy in the combination treatment of patients with locally advanced cervical cancer.Ovodenko D.L., Khabas G.N., Aleshikova O.I., Vashakmadze S.L., Pirogova M.S., Sannikova M.V., Makarova A.S., Sheshko P.L., Korshunov A.A., Ashrafyan L.A.
Subjects and methods. The results of examining 81 patients with locally advanced cervical cancer who had received combination treatment involving neoadjuvant chemotherapy and surgical treatment are given.
Results. Following neoadjuvant chemotherapy, radical hysterectomy was performed in 75 (92.6%) patients. The surgical interventions via laparoscopic and laparotomic accesses were comparatively analyzed and yielded the similar results.
Keywords
cervical cancer
laparoscopy
neoadjuvant chemotherapy
References
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Received 03.11.2016
Accepted 11.11.2016
About the Authors
Ovodenko Dmitry L., PhD, oncogynecologist, Department of combined and integrated methods of treatment of gynecological diseases, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117485, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954380988. E-mail: d_ovodenko@oparina4.ruKhabas Gregory N., MD, Ph.D., head of the Department of combined and integrated methods of treatment of gynecological diseases, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117485, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954380988. E-mail: g_khabas@oparina4.ru
Aleshikova Olga I., PhD, Senior Scientist Laboratory early carcinogenesis, prevention, diagnosis and combined treatment of cancer of the female reproductive organs,
Russian Scientific Center of Radiology and the Ministry of Health of Russia.
117997, Russia, Moscow, Profsoyuznaya str. 86. Tel.: +74991206077. E-mail: olga.aleshikova@gmail.com
Vashakmadze Sophiko L., graduate student of the department of early carcinogenesis, prevention, diagnosis and combined treatment
of cancer of the female reproductive organs, Russian Scientific Center of Radiology and the Ministry of Health of Russia.
117997, Russia, Moscow, Profsoyuznaya str. 86. Tel.: +74991206077. E-mail: v.sofia.l@gmail.com
Pirogova Maria S., oncologist of the Department of Breast Pathology, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117485, Russia, Moscow, Ac. Oparina str. 4. E-mail: m_pirogova@oparina4.ru
Sannikova Maya V., PhD, researcher at the Department of combined and integrated methods of treatment of gynecological diseases, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117485, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954380988. E-mail: m_sannikova@oparina4.ru
Makarova Anna S., doctor obstetrician-gynecologist, department of innovative oncology and gynecology, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117485, Russia, Moscow, Ac. Oparina str. 4
Sheshko Polina L., obstetrician-gynecologist, oncologist of the Department of Innovative Oncology and Gynecology, Research Center of Obstetrics,
Gynecology, and Perinatology, Ministry of Health of Russia. 117485, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954388540. E-mail: p_sheshko@oparina4.ru
Korshunov Alexey A., obstetrician-gynecologist, Department of combined and integrated methods of treatment of gynecological diseases, Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117485, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954380988. E-mail: a_korshunov@oparina4.ru
Ashrafyan Lev A., Corresponding Member of the Russian Academy of Sciences, Professor, MD, director of early carcinogenesis, prevention,
diagnosis and combined treatment of cancer of the female reproductive organs, Russian Scientific Center of Radiology and the Ministry of Health of Russia.
117997, Russia, Moscow, Profsoyuznaya str. 86. Tel.: +74991206077. E-mail: levaa2004@yahoo.com
For citations: Agarkov N.M., Gontarev S.N., Yakovlev A.P., Shulga L.V., Ivanov V.A. To rationalize the diagnosis of acute salpingoophoritis by the informative indicators of oxidative and antioxidative systems. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (4): 101-7. (in Russian)
http://dx.doi.org/10.18565/aig.2017.4.101-7
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