The microbiome of the upper female reproductive tract

Barinova V.V., Kuznetsova N.B., Bushtyreva I.O., Sokolova K.M., Polev D.E., Dudurich V.V.

1) Rostov State Medical University, Ministry of Health of Russia, Rostov-on-Don, Russia; 2) OOO «Professor Bushtyreva’s Clinic», Rostov-on-Don, Russia; 3) «Serbalab» Medical Genetics Center, Saint Petersburg, Russia
Many researchers have shown the relationship of different microbial communities to the human health status. The microorganisms that inhabit the upper and lower genital tract play a substantial role not only in dysbiotic states, but can also affect the success of conception and pregnancy. In addition, microbial associations were isolated from loci, such as the placenta, breast, uterus, fallopian tubes, which were previously considered sterile, by affecting the women’s health status. It is through the microbiome that a set of prenatal, postnatal, and intrapartum factors together with medical interventions and environmental factors influences the early childhood of the offspring and the health state in adulthood.

Keywords

microbiome
reproductive system
infertility
recurrent miscarriage

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Received 20.09.2019

Accepted 04.10.2019

About the Authors

Viktoriya V. Barinova, PhD, Assistant of the Department of Obstetrics and Gynecology No. 1 of Rostov State Medical University, Ministry of Health of the Russian Federation; aHead of the obstetric department of the Clinic of Professor Bushtyreva LLC. Phone: +79289095568, e-mail: victoria-barinova@yandex.ru
344022, Rostov-on-Don, str. Nakhichevanskiy, 29; 344011, Rostov-on-Don, str. Soborniy, 58/7.
Natalya B. Kuznetsova, PhD, Professor at the Center for Simulation Training at the Rostov State Medical University, Ministry of Health of the Russian Federation; Chief Doctor of the Clinic of Professor Bushtyreva LLC. Phone: +79287709762, e-mail: lauranb@inbox.ru
344022, Rostov-on-Don, str. Nakhichevanskiy, 29; 344011, Rostov-on-Don, str. Soborniy, 58/7.
Irina O. Bushtyreva, PhD, Professor, Director of the Clinic of Professor Bushtyreva LLC. Phone: +7928296-15-97, e-mail: kio4@mail.ru
344011, Rostov-on-Don, str. Soborniy, 58/7.
Kristina M. Sokolova, obstetrician-gynecologist at the Clinic of Professor Bushtyreva LLC, address:
344011, Rostov-on-Don, str. Sobornyi, 58/7, tel. +79188582179, e-mail: kris.vasilega2014@yandex.ru
344011, Rostov-on-Don, str. Soborniy, 58/7.
Dmitry E. Polev, chief biologist of the medical and genetic center «Serbalab», PhD in biology with a degree in genetics.
Phone: +79112560523, e-mail: vdudurich@cerbalab.ru. 199106, Russia, St. Petersburg, Bolshoy ave. Vasilyevsky Island, d. 90, bldg. 2.
Vasilisa V. Dudurich, geneticist, biologist, development director of the medical and genetic center «Serbalab». Phone:+79145422010, e-mail: vdudurich@cerbalab.ru
199106, Russia, St. Petersburg, Bolshoy ave. Vasilyevsky Island, d. 90, bldg. 2.

For citation: Barinova V.V., Kuznetsova N.B., Bushtyreva I.O., Sokolova K.M., Polev D.E., Dudurich V.V. The microbiome of the upper female reproductive tract.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2020; 3: 12-17.(In Russian).
https://dx.doi.org/10.18565/aig.2020.3.12-17

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