Menopausal vasomotor symptoms: social aspects, dynamics, cardiometabolic risks, hormone therapy options

Yureneva S.V., Ilyina L.M., Ebzieva Z.K.

1 National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Moscow, Russia 2 Association of Gynecologists and Endocrinologists, Moscow, Russia
Vasomotor symptoms (hot flashes and night sweats) are the most characteristic symptoms of menopause. However, mounting evidence points to hot flashes as a manifestation of underlying autonomic neurovascular dysregulation that put an individual woman at risk for chronic conditions of aging. The review addresses the following issues: women’s attitudes towards menopause and hot flashes, the dynamics and duration of vasomotor symptoms across the different stages of reproductive aging, vasomotor symptoms as markers of cardiometabolic risk and their relationship with sleep disturbance, advantages of menopausal hormonal therapy with antimineralocorticoid progestin.


menopausal vasomotor symptoms
hot flashes
night sweats
cardiometabolic risks
sleep disturbance
renin‐angiotensin‐aldosterone system
menopause hormone therapy


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Received 06.12.2018

Accepted 07.12.2018

About the Authors

Yureneva, Svetlana V., MD, senior researcher of the Department of Gynecological Endocrinology, professor of the Department of Obstetrics and Gynecology of Academician
V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79161797400.
Ilyina, Lilia M., MD, medical advisor on menopause for Association of gynecologists and endocrinologists.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79152101931. E-mail:
Ebzieva, Zukhra K., graduate student of the Department of Gynecological Endocrinology of Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +7252580319.

For citations: Yureneva S.V., Ilyina L.M., Ebzieva Z.K. Menopausal vasomotor symptoms: social aspects, dynamics, cardiometabolic risks, hormone therapy options. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2019; (1): 26-32. (in Russian)

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