Minor cervical lesions associated with human papillomavirus: diagnosis, monitoring, prognosis

Sycheva E.G., Nazarova N.M., Prilepskaya V.N., Burmenskaya O.V.

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow 117997, Ac. Oparina str. 4, Russia
Objective. To estimate the incidence of minor cervical lesions and to analyze methods for their diagnosis.
Material and methods. The paper reviews the published literature on minor cervical epithelial lesions, methods for their diagnosis, and prognosis of disease progression
Results. The analysis of the data available in the literature has shown that molecular genetics and immunocytochemical methods greatly expand the diagnostic capabilities of minor lesions and the prognosis of the course of the process.
Conclusion. It is necessary to search for molecular genetic markers to assess the risk of progression of the process.


minor cervical lesions
cervical intraepithelial neoplasia
human papillomavirus
cervical cancer

Supplementary Materials

  1. Table. The carcinogenic groups risk depending on the type of HPV (IARC, 2012 г.)


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Received 09.06.2017

Accepted 23.06.2017

About the Authors

Sycheva Elena Gennadievna, doctor, Research Centre of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79104925455. E-mail: el.bona@mail.ru
Nazarova Niso Mirzoevna, MD, PhD, Senior Researcher, Research Centre of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia.
117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954381403. E-mail: grab2@yandex.ru
Prilepskaya Vera Nikolaevna, MD, PhD, Professor, Deputy Director for Science, Research Centre of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +74954386934. E-mail: VPrilepskaya@mail.ru
Burmenskaya Olga Vladimirovna, MD, Senior Researcher of Laboratory molecular genetic factors, Research Centre of Obstetrics, Gynecology and Perinatology,
Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79167531709. E-mail: bourmenska@mail.ru

For citations: Sycheva E.G., Nazarova N.M., Prilepskaya V.N., Burmenskaya O.V. Minor cervical lesions associated with human papillomavirus: diagnosis, monitoring, prognosis. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (4): 125-30. (in Russian)

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