Correction of iron-deficiency anemia in pregnant women
Objective. To investigate the efficiency of Tardyferon treatment for manifest iron deficiency in pregnant women.Tyutyunik V.L., Kan N.E., Mikhailova O.I.
Subjects and methods. A total of 108 women with singleton pregnancy and mild iron-deficiency anemia (IDA) have been followed up during 2017-2018. Group 1 (a study group) consisted of 55 pregnant women treated for IDA with an iron sulfate-containing drug (Tardyferon); Group 2 (a comparison group) comprised 53 pregnant women treated for IDA with iron (III)-hydroxide polymaltosate complex containing 100 mg of iron.
Results. The key hemogram indicators in Group 1 patients treated with Tardyferon were higher than those in Group 2. Side effects were noted in 21 (39.6%) patients treated with iron (III)-hydroxide polymaltose complex and in 5 (9.1%) pregnant women using Tardyferon, which suggests its good tolerance and, accordingly, high treatment adherence.
Conclusion. The anemic pregnant women treated with iron preparations show a significant normalization of ferrokinetic parameters, which leads to improved tissue oxygenation and favorable changes in a pregnant women with anemia and, as a result, to a positive clinical effect.
Keywords
iron-deficiency anemia
pregnancy
iron preparations
References
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Received 08.06.2018
Accepted 22.06.2018
About the Authors
Tyutyunnik, Victor L., MD, head of the 1st Obstetric Physiological Department, National Medical Research Center of Obstetrics, Gynecology, and Perinatology Academician named after V.I. Kulakov, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79039695041. E-mail: tioutiounnik@mail.ru.Researcher ID B-2364-2015. ORCID ID 0000-0002-5830-5099
Kan, Natalia E., MD, head of the obstetric department, National Medical Research Center of Obstetrics, Gynecology, and Perinatology Academician named after V.I. Kulakov, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79262208655. E-mail: kan-med@mail.ru.
Researcher ID B-2370-2015. ORCID ID 0000-0001-5087-5946
Mikhailova, Olga I., Ph.D., scientific employee of obstetric department, National Medical Research Center of Obstetrics, Gynecology, and Perinatology Academician named after V.I. Kulakov, Ministry of Health of Russia. 117997, Russia, Moscow, Ac. Oparina str. 4. Tel.: +79265646813. E-mail: o_mikhailova@oparina4.ru
For citations: Tyutyunik V.L., Kan N.E., Mikhailova O.I. Correction of iron-deficiency anemia in pregnant women. Akusherstvo i Ginekologiya/Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2018; (8): 106-10. (in Russian)
https://dx.doi.org/10.18565/aig.2018.8.106-110
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