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The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
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Obstetrics and Gynegology2020№3
Quality of life in patients...

Quality of life in patients with deep infiltrating endometriosis

DOI
https://dx.doi.org/10.18565/aig.2020.3.116-126

Lisovskaya E.V., Khilkevich E.G., Chuprynin V.D., Melnikov M.V., Ipatova M.V.

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, Moscow
Objective. To analyze the time course of changes in quality-of-life (QoL) indicators in women with deep infiltrating endometriosis (DIE) before and after surgical treatment.
Subjects and methods. The investigation enrolled 93 women with DIE who underwent surgical treatment at the Surgical Department, V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia, in 2017 to 2019 (a study group); 47 of whom completed the study in 2019, and 31 women without endometriosis (a control group). The SF-36 questionnaire was used to assess QoL in the patients at admission to hospital and 6-8 months after surgical treatment. According to the location of a DIE focus, the study group patients were divided into four subgroups, by using the Enzian classification. QoL indicators in the study group patients were comparatively analyzed according to the size of the largest focus, the presence of infertility, and surgical interventions in the history of patients.
Results. The study confirmed that DIE significantly affected all components of the women’s QoL. The localization of the lesion and its extent had no considerable impact on QoL. Statistically significantly higher indicators were found on the scales of social functioning, vital activity, pain intensity (PI), and physical functioning (PF) in women with complaints of infertility. Comparative characterization of QoL indicators in women with a history of surgical treatment revealed that the indicators were statistically significantly higher (p < 0.05) on the scales of PI, PF, and a physical health component. Surgical treatment leads to an improvement in all QoL indicators in women with DIE at 6-8 months postsurgery. There were no statistically significant differences on the scales of overall-health self-assessment, PF, and role emotional functioning.
Conclusion. DIE leads to a significant decrease in all QoL indicators in women, regardless of the location of a focus and its sizes. QoL in women with DIE, the main complaint of which is infertility, is higher than that in those who have an extensive clinical symptomatology of the disease, but do not suffer from infertility. Surgical removal of foci is an effective method with a long partial effect; however, it should be likely to be supplemented with psychotherapy.

Keywords

deep infiltrating endometriosis
quality of life
surgical treatment
Full text (in Russian)

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Received 15.01.2020

Accepted 07.02.2020

About the Authors

Ekaterina V. Lisovskaya, obstetrician-gynecologist of the surgical department of the department of operative gynecology and general surgery, National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russia. Tel.: +7 (495) 438-78-33.
E-mail: e_lisovskaya@oparina4.ru
Address:117997, Russia, Moscow, Ac. Oparina str. 4.
Elena G. Khilkevich, MD, obstetrician–gynecologist of the Surgery Department, National Medical Research Center for Obstetrics, Gynecology and Perinatology named
after Academician V.I. Kulakov, Ministry of Health of Russia. Tel.: +7 (495)438-78-33. E–mail: e_khilkevich@oparina4.ru. ORCID ID: 0000–0001–8826–8439
Address:117997, Russia, Moscow, Ac. Oparina str. 4.
Vladimir D. Chuprynin, PhD, Head of the Surgery Department, National Medical Research Center for Obstetrics, Gynecology, and Perinatology named
after Academician V.I. Kulakov, Ministry of Health of Russia. Tel.: +7(495) 438-78-33. E–mail: v_chuprynin@oparina4.ru
Address:117997, Russia, Moscow, Ac. Oparina str. 4.
Mikhail V. Melnikov, candidate of medical sciences, head. on the clinical work of the surgical department of the Department of Operative Gynecology and General Surgery, National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russia.
Tel.: +7 (495) 438-78-33. E-mail: m_melnikov@oparina4.ruAddress: 117997, Russia, Moscow, ul. Academician Oparin, d. 4.
Ipatova Marina V., PhD, head of the gynecology department of Rehabilitation National Medical Research Center for Obstetrics, Gynecology and Perinatology named
after Academician V.I.Kulakov of Ministry of Healthcare of Russian Federation. Tel.:+7 (495)438-23-44. E-mail: m_ipatova@oparina4.ru
117997 Russian Federation, Moscow, Oparin street, 4.

For citation: Lisovskaya E.V., Khilkevich E.G., Chuprynin V.D., Melnikov M.V., Ipatova M.V. Quality of life in patients with deep infiltrating endometriosis.
Akusherstvo i Ginekologiya/ Obstetrics and gynecology. 2020; 3: 116-26. (In Russian).
https://dx.doi.org/10.18565/aig.2020.3.116-126

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