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The Journal "Obstetrics and Gynecology"Journal HistoryAims and ScopePolicies on Conflict of Interest, Human and Animal Rights, and Informed ConsentEditorial ProcessData sharing statementAdvertising PolicyThe Process for Handling Cases Requiring Corrections, Retractions, and Editorial Expressions of ConcernEditorial BoardEditorial CounsilInformation for ProfessionalsNewsContacts
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Obstetrics and Gynegology2025№7
Characteristics of nutritional status in...

Characteristics of nutritional status in endometriosis and pain syndrome

DOI
https://dx.doi.org/10.18565/aig.2025.131

Alieva P.M., Smetnik A.A., Moskvicheva Yu.B., Dumanovskaya M.R., Tabeeva G.I., Ermakova E.I., Fateeva E.M., Solopova A.E., Pavlovich S.V.

1) Academician V.I. Kulakov National Medical Research Centre for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia, Moscow, Russia 2) I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia

Objective: To analyze and evaluate the nutritional status and nutritional components with potential pro-inflammatory and anti-inflammatory effects in the diet of patients with endometriosis, as well as to study the possible relationship between the nutritional status and intensity of pain syndrome.
Materials and methods: The study included 58 patients aged 19 to 44 years with various forms of endometriosis and pain syndrome. The pain syndrome was assessed using the visual analog scale (VAS) and numeric rating scale (NRS). The nutritional status was assessed by frequency analysis using a computer program developed by the Scientific Research Institute of Nutrition of the Russian Academy of Medical Sciences, 2003–2006 (version 1.2.4). Statistical data processing was performed using IBM SPSS Statistics 27.0.
Results: The comparison of the indicators with the recommended dietary allowance (RDA) of substances showed a deficiency in such important micronutrients as magnesium (Mg), calcium (Ca) (in groups with reduced BMI (rBMI) and high BMI (hBMI), iron, as well as vitamins B1, B2 and B3. Insufficient intake of legumes and whole grains was associated with a lower intake of magnesium in the patients of the study groups. Its values were lower than the median RDA (420 mg/day), namely: 190.1 mg in patients with rBMI, p<0.001 (RDA); 317.2 mg in patients with normal BMI (nBMI), 267.2 mg in patients with hBMI. Calcium intake was significantly decreased in women with rBMI and hBMI (610.8 mg and 798.2 mg, p<0.05; RDA of calcium is 1000 mg/day). Excessive consumption of processed meat products (sausages) and semi-finished products led to an increase in the consumption of table salt in patients of all three groups, which naturally caused an increase in sodium intake. There were no significant differences in the intensity of pain syndrome among the patients according to NRS and VAS.
Conclusion: The revealed characteristics of the nutritional status of patients with endometriosis demonstrate the potential for the development of novel therapeutic approaches to pain management. Dietary correction can become a component of complex pain therapy in this category of patients and contribute to improving their quality of life.

Authors’ contributions: Alieva P.M., Moskvicheva Yu.B., Dumanovskaya M.R. – developing the concept and design of the study; Alieva P.M., Moskvicheva Yu.B., Dumanovskaya M.R., Smetnik A.A. – collecting and processing the material, statistical data processing; Alieva P.M., Moskvicheva Yu.B., Fateeva E.M., Dumanovskaya M.R. – writing the text of the article; Tabeeva G.I., Ermakova E.I., Solopova A.E., Pavlovich S.V. – editing the article.
Conflicts of interest: Authors declare lack of the possible conflicts of interest.
Funding: The study was conducted without sponsorship.
Ethical Approval: The study was approved by the Ethical Review Board of the Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia.
Patient Consent for Publication: The patients signed informed consent for the publication of their data.
Authors' Data Sharing Statement: The data supporting the findings of this study are available on request from the corresponding author after approval from the principal investigator.
For citation: Alieva P.M., Smetnik A.A., Moskvicheva Yu.B., Dumanovskaya M.R., Tabeeva G.I., Ermakova E.I., Fateeva E.M., Solopova A.E., Pavlovich S.V. Characteristics of nutritional status in endometriosis and pain syndrome.
Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2025; (7): 92-102 (in Russian)
https://dx.doi.org/10.18565/aig.2025.131

Keywords

endometriosis
diet
pain syndrome
nutrition
Full text (in Russian)

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Received 15.05.2025

Accepted 01.07.2025

About the Authors

Patimat M. Alieva, obstetrician-gynecologist, PhD student at the Department of Gynecological Endocrinology, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, aalievapm@gmail.com, https://orcid.org/0009-0007-1391-3211
Antonina A. Smetnik, PhD, Head of the Department of Gynecological Endocrinology, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia,
117997, Russia, Moscow, Ac. Oparin str., 4, a_smetnik@oparina4.ru, https://orcid.org/0000-0002-0627-3902
Yulia B. Moskvicheva, doctor-nutritionist at the Department of Gynecological Endocrinology, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia,
117997, Russia, Moscow, Ac. Oparin str., 4, yu_moskvicheva@oparina4.ru, https://orcid.org/0009-0000-0114-4960
Madina R. Dumanovskaya, PhD, Senior Researcher at the Department of Gynecological Endocrinology, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia,
117997, Russia, Moscow, Ac. Oparin str., 4, m_dumanovskaya@oparina4.ru, https://orcid.org/0000-0001-7286-6047
Gyuzal I. Tabeeva, PhD, Senior Researcher at the Department of Gynecological Endocrinology, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia,
117997, Russia, Moscow, Ac. Oparin str., 4, g_tabeeva@oparina4.ru, https://orcid.org/0000-0003-1498-6520
Elena I. Ermakova, PhD, Senior Researcher at the Department of Gynecological Endocrinology, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia,
117997, Russia, Moscow, Ac. Oparin str., 4, e_ermakova@oparina4.ru, https://orcid.org/0000-0002-6629-051X
Evgeniya M. Fateeva, Resident, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4, konat158@gmail.com,
https://orcid.org/0000-0003-3060-7113
Alina E. Solopova, Dr. Med. Sci., Leading Researcher at the Department of Radiation Diagnostics, Department of Visual Diagnostics, V.I. Kulakov NMRC for OG&P,
Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4; Professor, Department of Obstetrics, Gynecology, Perinatology and Perinatal Medicine,
I.M. Sechenov First MSMU, Ministry of Health of Russia (Sechenov University), 119991, Russia, Moscow, Trubetskaya, 8-2, a_solopova@oparina4.ru,
https://orcid.org/0000-0003-4768-115X
Stanislav V. Pavlovich, PhD, Scientific Secretary, V.I. Kulakov NMRC for OG&P, Ministry of Health of Russia, 117997, Russia, Moscow, Ac. Oparin str., 4; Professor, Department of Obstetrics, Gynecology, Perinatology and Reproductology, I.M. Sechenov First MSMU, Ministry of Health of Russia (Sechenov University),
119991, Russia, Moscow, Trubetskaya str., 8-22, s_pavlovich@oparina4.ru, https://orcid.org/0000-0002-1313-7079
Corresponding author: Patimat M. Alieva, aalievapm@gmail.com

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