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Obstetrics and Gynegology2023№10
Incidence and severity of premenstrual...

Incidence and severity of premenstrual syndrome among Russian and foreign female medical college students according to the Russian version of the validated premenstrual syndrome symptom questionnaire

DOI
https://dx.doi.org/10.18565/aig.2023.230

Yavorskaya S.D., Dmitrienko K.V., Lebedeva E.I., Nemtseva G.V.

Altai State Medical University, Ministry of Health of the Russian Federation, Barnaul, Russia

Relevance: Premenstrual syndrome (PMS) is prevalent in women of reproductive age. However, data on PMS incidence and symptomatology among female students in medical colleges, as well as differences based on nationality and socioeconomic status, are insufficient in existing literature. Objective: This study aimed to determine the incidence, symptoms, and severity of PMS among Russian and foreign female students in a medical college, using the validated Russian version of the Royal College of Obstetricians and Gynecologists PMS Symptom Questionnaire. Materials and methods: An anonymous questionnaire survey using the Google Form format was conducted among 186 female students, including 152 students from the Institute of Clinical Medicine (Group 1) and 34 students from the Faculty of International Students (Group 2). Results: The study found a high incidence of PMS in both groups (77.6 and 82.3%) with different ethnicity, socioeconomic status, and medical history. However, the frequency of seeking medical help for PMS symptoms was relatively low (39.5 and 29.4%). The most common symptoms reported by participants in this age group (21–25 years) and social status included low mood and depression (84.2 and 100%), decreased performance (65.1 and 94.1%), symptoms of anxiety and/or muscle tension (83.6% and 91.2%), and mastalgia and/or mastodynia (73.6 and 61.8%). A majority of respondents reported discomfort and a significant decrease in their quality of life in the week before menstruation (72.0 and 53.6%). Furthermore, moderate or severe PMS was found to be twice as common among female international students (15.3 and 32.2%). Conclusion: The study found that female medical students are at high risk for developing PMS (78.5%), with international female students demonstrating more severe symptoms. Considering the nature of PMS symptoms in both Russian and foreign female students, treatment containing Vitex agnus-castus extract may be a pathogenetically justified first-line treatment approach.

Authors' contributions: Yavorskaya S.D. – conceptualization, conducting research, drafting and editing of the manuscript, approval of the final version of the manuscript; Dmitrienko K.V. – conducting research, statistical analysis, drafting the literature review; Lebedeva E.I. – conducting research, statistical analysis; Nemtseva G.V. – conducting research, drafting and editing of the manuscript.

Conflicts of interest: The authors have no conflicts of interest to declare.

Funding: There was no funding for this study.

Ethical Approval: The study was reviewed and approved by the Research Ethics Committee of the Altai State Medical University, Ministry of Health of Russia.

Patient Consent for Publication: All patients provided informed consent for the publication of their data.

Authors' Data Sharing Statement: The data supporting the findings of this study are available upon request from the corresponding author after approval from the principal investigator.

For citation: Yavorskaya S.D., Dmitrienko K.V., Lebedeva E.I., Nemtseva G.V. Incidence and severity of premenstrual syndrome among Russian and foreign female medical college students according to the Russian version of the validated premenstrual syndrome symptom questionnaire. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2023; (10): 141-150 (in Russian) https://dx.doi.org/10.18565/aig.2023.230

Keywords

female medical students
premenstrual syndrome
therapy
questionnaire for PMS symptom identification
Vitex agnus-castus
Full text (in Russian)

References

  1. Retallick-Brown H., Blampied N., Rucklidge J.J. A pilot randomized treatment-controlled trial comparing vitamin B6 with broad-spectrum micronutrients for premenstrual syndrome. J. Altern. Complement. Med. 2020; 26(2): 88-97. https//dx.doi.org/10.1089/acm.2019.0305.
  2. Dutta A., Sharma A. Prevalence of premenstrual syndrome and premenstrual dysphoric disorder in India: a systematic review and meta-analysis. Health Promot Perspect. 2021; 11(2): 161-70. https//dx.doi.org/10.34172/hpp.2021.20.
  3. Al-Abdulla S., El-Amin Ah., Shehata M., Aly Sh., Al Emadi N., Al-Meer F., Al-Amin H. Premenstrual dysphoric disorder in Arab women: validation and cultural adaptation of the Arabic version of the premenstrual screening tool. Women Health. 2019; 59(6): 631-45. https//dx.doi.org/10.1080/03630242.2018.1539433.
  4. Jaber R.M., Alghzawi A.O., Salameh H.H. Premenstrual syndrome: consultation sources and the impact on women's quality of life. Afr. Health Sci. 2022; 22(1): 80-7. https//dx.doi.org/10.4314/ahs.v22i1.10.
  5. Логинова К.Б., Дюкова Г.М., Доброхотова Ю.Э. Предменструальный синдром в популяции женщин Российской Федерации (эпидемиологическое исследование). Проблемы репродукции. 2019; 25(1): 34-40. [Loginova K.B., Diukova G.M., Dobrokhotova Iu.É. Premenstrual syndrome in the population of women of the Russian Federation (epidemiological survey). Russian Journal of Human Reproduction. 2019; 25(1): 34 40. (in Russian)]. https://dx.doi.org/10.17116/repro20192501134.
  6. Management of premenstrual syndrome: Green top Guideline No. 48. BJOG. 2017; 124(3): e73-e105. https//dx.doi.org/10.1111/1471-0528.14260.
  7. Wallenstein G.V., Blaisdell-Gross B., Gajria K., Guo A., Hagan M., Kornstein S.G. et al. Development and validation of the Premenstrual Symptoms Impact Survey (PMSIS): a disease-specific quality of life assessment tool. J. Womens Health. 2008; 17(3): 439-50. https://dx.doi.org/10.1089/jwh.2007.0377.
  8. Kues J.N., Janda C., Kleinstäuber M., Weise C. How to measure the impact of premenstrual symptoms? Development and validation of the German PMS-Impact Questionnaire. Women Health. 2016; 56(7): 807-26. https://dx.doi.org/10.1080/03630242.2015.1118734.
  9. Yonkers K.A., Simoni M.K. Premenstrual disorders. Am. J. Obstet. Gynecol. 2018; 218(1): 68-74. https//dx.doi.org/10.1016/j.ajog.2017.05.045.
  10. Елгина С.И., Кинтикова И.А., Попов А.О., Мозес В.Г., Рудаева Е.В., Мозес К.В., Черных Н.С. Предменструальный синдром у студенток медицинского ВУЗа. Частота. Клинические проявления. Медицина в Кузбассе. 2022; 21(3): 65-8. [Еlgina S.I., Kintikova I.A., Popov A.O., Moses V.G., Rudaeva E.V., Moses K.B., Chernykh N.S. Premenstrual syndrome in female medical students. Frequency. clinical Manifestations. Medicine in Kuzbass. 2022; 21(3): 65-8. (in Russian)]. https//dx.doi.org/10.24412/2687-0053-2022-3-65-68.
  11. Черненкова М.Л., Валеева И.Р., Тимирова Р.Р. Характер симптомов и тяжесть течения предменструального синдрома у студенток Ижевской государственной медицинской академии. Здоровье, демография, экология финно-угорских народов. 2022; 2: 31-3. [Chernenkova M.L., Valeeva I.R., Timirova R.R. The character of symptoms and severity of premenstrual syndrome in female students of Izhevsk State Medical Academy. Health, Demography, Ecology of Finno-Ugric peoples. 2022; (2): 31-3. (in Russian)].
  12. Верхотурова Д.Г., Воронцова А.В. Предменструальный синдром – так ли это важно для студенток медицинского университета. В кн.: Божко Я.Г., ред. Актуальные вопросы современной медицинской науки и здравоохранения: материалы VI Международной научно-практической конференции молодых ученых и студентов, посвященной году науки и технологий. Екатеринбург, 8–9 апреля 2021 г. Екатеринбург: УГМУ; 2021; т.1: 42-7. [Verkhoturova D.G., Vorontsova A.V. Premenstrual syndrome – is it important for medical university students. In: Topical issues of modern medical science and health care. Materials of the VI International Scientific and Practical Conference of Young Scientists and Students dedicated to the year of science and technology. Ekaterinburg: USMU; 2021; vol. 1: 42-7. (in Russian)].
  13. Tolossa F.W., Bekele M.L. Prevalence, impacts and medical managements of premenstrual syndrome among female students: cross-sectional study in college of health sciences, Mekelle University, Mekelle, Northern Ethiopia. BMC Womens Health. 2014; 14(1): 52. https://dx.doi.org/10.1186/1472-6874-14-52.
  14. Кузнецова И.В. Современные представления о терапии предменструального синдрома. Медицинский алфавит. 2019; 3(25): 18-23. [Kuznetsova I.V. Modern views on treatment of premenstrual syndrome. Medical Alphabet. 2019; 3(25): 18-23. (in Russian)]. https://dx.doi.org/10.33667/2078-5631-2019-3-25(400)-18-23.
  15. Андреева Е.Н., Абсатарова Ю.С. Предменструальный синдром: обзор литературы. Гинекология. 2019; 21(2): 38-43. [Andreeva E.N., Absatarova Yu.S. Premenstrual syndrome: a review of the literature. Gynecology. 2019; 21(2): 38-43. (in Russian)]. https//dx.doi.org/10.26442/20795696.2019.2.190341.
  16. Appleton S.M. Premenstrual syndrome: Evidence-based evaluation and treatment. Clin. Obstet. Gynecol. 2018; 61(1): 52-61. https//dx.doi.org/10.1097/GRF.0000000000000339.
  17. Purnawati J., Sinrang A.W., Jusuf E.C., Limoa E., Ahma M., Usman A.N. Nutrition, mental status and level of 8-hydroxy-2-deoxyguanosine (OHDG) urine as predictors of premenstrual syndrome (PMS) in adolescent girls. Int. J. Curr. Res. Rev. 2020; 12(2): 7-13. https://dx.doi.org/10.31782/IJCRR.2020.122315.
  18. Alimoradi Z., Jafari El., Broström A., Ohayon M.M., Lin Ch. Y., Griffiths M.D. et al. Reply to Liu et al.: " Effects of cognitive behavioral therapy for insomnia (CBT-I) on quality of life: a systematic review and meta-analysis". Sleep Med. Rev. 2022; 64: 101646. https//dx.doi.org/10.1016/j.smrv.2022.101646.
  19. Çitil E.T., Kaya N. Effect of pilates exercises on premenstrual syndrome symptoms: a quasi-experimental study Complement. Ther. Med. 2021; 57: 102623. https//dx.doi.org/10.1016/j.ctim.2020.102623.
  20. Сидорова Т.Н., Левицкая В.М., Охотина Т.Н., Жамлиханова С.С. Обеспеченность витамином D девушек-студенток с предменструальным синдромом. Медико-фармацевтический журнал «Пульс». 2019; 21(9): 12-7. [Sidorova T.N., Levitskaya V.M., Okhotina T.N., Zhamlikhanova S.S. The provision of vitamin D for female students with premenstrual syndrome. Medical and Pharmaceut. Journal “Pulse”. 2019; 21(9): 12-7. (in Russian)]. https//dx.doi.org/10.26787/nydha-2686-6838-2019-21-9-12-17.
  21. Abdi F., Ozgoli G.,Rahnemaie S.F. A systematic review of the role of vitamin D and calcium in premenstrual syndrome. Obstet. Gynecol. Sci. 2019; 62(2): 73-86. https//dx.doi.org/10.5468/ogs.2019.62.2.73.
  22. Yonker K.A., Simoni M.K. Premenstrual disorders. Am. J. Obstet. Gynecol. 2018; 218(1): 68-74. https//dx.doi.org/10.1016/j.ajog.2017.05.045.
  23. Shoaee F., Pouredalati M., Dadshahi S., Parvin P., Bolourian M., Kiani A. et al. Evaluation of non-pharmacological strategies, therapeutic and cognitive-behavioral interventions in the treatment of premenstrual syndrome: a review study. Int. J. Pediatr. 2020; 8(2): 10929-39. https//dx.doi.org/10.22038/ijp.2020.46333.3771.
  24. Dickerson L.M., Mazyck P.J., Hunter M.H. Premenstrual syndrome. Am. FAM Physician. 2003; 67(8): 1743-52.
  25. Sultana A., Rahman K., Bin Heyat M.B., Sumbul, Akhtar F., Muaad A.Y. Role of inflammation, oxidativesStress, and mitochondrial changes in premenstrual psychosomatic behavioral symptoms with anti-inflammatory, antioxidant herbs, and nutritional supplements. Oxi.d Med. Cell. Longev. 2022; 2022: 3599246. https://dx.doi.org/10.1155/2022/3599246.
  26. Teodoro A.J. Bioactive compounds of food: their role in the prevention and treatment of diseases. Oxid. Med. Cell. Longev. 2019; 2019: 3765986. https//dx.doi.org/10.1155/2019/3765986.
  27. Naoi M., Shamoto-Nagai M., Maruyama W. Neuroprotection of multifunctional phytochemicals as novel therapeutic strategy for neurodegenerative disorders: antiapoptotic and antiamyloidogenic activities by modulation of cellular signal pathways. Future Neurol. 2019; 14(1): FNL9. 10.2217/fnl-2018-0028.
  28. Allen J., Romay-Tallon R., Brymer k.J., Caruncho H.J., Kalynchuk L.E. Mitochondria and mood: mitochondrial dysfunction as a key player in the manifestation of depression. Front. Neurosci. 2018; 12: 386. https//dx.doi.org/10.3389/fnins.2018.00386.
  29. Клинический протокол диагностики и лечения. Синдром предменструального расстройства. 2021. [Clinical protocol for diagnosis and treatment. Premenstrual disorder syndrome. 2021. (in Russian)]. Available at: https://umc.org.kz/wp-content/uploads/2022/09/kp-sindrom-predmenstrualnogo-napryazheniya.pdf
  30. Халимова Ф.Т., Кароматов И.Д., Исоева Б.И. Фитоэстрогены в гинекологии (обзор литературы. Электронный научный журнал «Биология и интегративная медицина». 2023; 1(60): 82-143. [Khalimova F.T., Karomatov I.D., Isoeva B.I. Phytoestrogens in gynecology (literature review). BIOINTEGMED. 2023; 1(60): 82-143. (in Russian)].
  31. Зайченко А.В., Процька В.В., Журавель И.А., Кисличенко В.С., Ходаковская О.В. Перспективы применения лекарственных средств на основе экстракта плодов Витекса священного для коррекции симптомов гормонального дисбаланса у женщин. Репродуктивное здоровье. Восточная Европа. 2021; 11(6): 806-19. [Zaychenko A., Protska V., Zhuravel I., Kyslychenko V., Khodakivska O. Prospects for the use of drugs based on Vitex Fruit extract for the correction of symptoms of hormonal imbalance in women. Reproductive Health. Eastern Europe. 2021; 11(6):806-19. (in Russian)]. https//dx.doi.org/10.34883/PI.2021.11.6.015.
  32. Бурчаков Д.И., Бурчакова М.Н. «Здоровое нездоровье»: предменструальный синдром в нарративах пациенток. Женская клиника. 2021; 2: 80-6. [Burchakov D.I., Burchakova M.N. «The healthy malaise»: premenstrual syndrome in patients’ narratives. Women's Clinic. 2021; (2): 80-6. (in Russian)].
  33. Адамов Г.В., Мельников Е.С., Лупанова И.А. Изучение химического состава и дофаминергической активности плодов Витекса священного (Vitex agnus-castus L.). Разработка и регистрация лекарственных средств. 2020; 9(3): 143-9. [Adamov G.V., Melnikov E.S., Lupanova I.A., Radimich A.I., Saybel O.L. Investigation of the Chemical Composition and Dopaminergic Activity of the Vitex Agnus-castus Fruits. Drug Development & Registration. 2020; 9(3): 143-9. (in Russian)]. https://dx.doi.org/10.33380/2305-2066-2020-9-3-143-149.
  34. Прилепская В.Н., Довлетханова Э.Р. Предменструальный синдром: клиника, диагностика, фитотерапия (клиническая лекция). Медицинский совет. 2020; 13: 106-15. [Prilepskaya V.N., Dovletkhanova E.R. Premenstrual syndrome: symptoms, diagnostics, phytotherapy (clinical lecture). Medical Council. 2020; (13): 106-15. (in Russian)]. https://dx.doi.org/10.21518/2079-701X-2020-13-106-115.
  35. Бурчаков Д.И., Ших Е.В. Витекс священный: от античных легенд к нейрофизиологии дофаминергического ответа на стрессовые стимулы. Женская клиника. 2020; 1: 17-23. [Burchakov D.I., Shikh E.V. Vitex agnus castus: from the antique legends to neurophysiology of dopaminergic stress response. Women's Clinic. 2020; (1): 17-23. (in Russian)].
  36. Семичковский Л.А. Препараты на основе витекса священного в маммологии (аналитический обзор литературы). Репродуктивное здоровье. Восточная Европа. 2019; 9(4): 521-9. [Semichkovski L. Preparations based on Vitex agnus-castus in mammology (analytical review of the literature). Reproductive Health. Eastern Europe. 2019; 9(4): 521-9. (in Russian)].
  37. Инструкция по медицинскому применению лекарственного препарата Циклодинон. Регистрационный номер: П N013429/01. [Prescribing Information for Cyclodinone. Registration number: P N013429/01. (in Russian)]. Available: at: https://cyclodynon.ru/sites/default/files/2023-03/Циклодинон_таб_полная%20инструкция_24.03.2021.pdf
  38. Вуттке В., Зайдлова-Вуттке Д., Ярри Г., Артымук Н.В. Роль Витекса священного (Vitex agnus castus) в гинекологической эндокринологии. Гинекология. 2012; 14(1): 8-11. [Wuttke W., Zaidlova-Wuttke D., Jarry H., Artymuk N. The role of Vitex agnus castus in gynecological endocrinology. Gynecology. 2012; 14(1): 8-11. (in Russian)].
  39. Кузнецова И.В., Успенская Ю.Б., Диль В.В., Гринева А.М. Использование растительных дофаминомиметиков у подростков и молодых женщин с нарушенным менструальным циклом. Акушерство и гинекология. 2015; 11: 70-7. [Kuznetsova I.V., Uspenskaya Yu.B., Dil V.V., Grineva A.M. Use of herbal dopamine mimetics in adolescents and young women with menstrual irregularities. Obstetrics and Gynecology. 2015; (11): 70-7. (in Russian)].
  40. Ледина А.В., Прилепская В.Н. Предменструальный синдром: возможности дифференцированного подхода к лечению. Акушерство и гинекология. 2018; 11: 92-7. [Ledina A.V., Prilepskaya V.N. Premenstrual syndrome: opportunities for a differentiated approach to treatment. Obstetrics and Gynecology. 2018; (11): 92-7. (in Russian)]. https://dx.doi.org/10.18565/aig.2018.11.92-97.
  41. Кулагина Н.В., Одинцов В.А. Мастодиния: патогенез, диагностика, лечение. Акушерство и гинекология. 2022; 6: 33-9. [Kulagina N.V., Odintsov V.A. Mastodynia: pathogenesis, diagnosis, and treatment. Obstetrics and Gynecology. 2022; (6): 33-9. (in Russian)]. https://dx.doi.org/10.18565/aig.2022.6.33-39.

Received 06.10.2023

Accepted 17.10.2023

About the Authors

Svetlana D. Yavorskaya, Professor, Department of Obstetrics and Gynecology, Altai State Medical University, Ministry of Health of Russia, +7(962)7927942, L2001@bk.ru, https://orcid.org/0000-0001-6362-5700, 656038, Russia, Barnaul, Lenina str., 40.
Ksenia V. Dmitrienko, PhD, Associate Professor, Department of Obstetrics and Gynecology, Altay State Medical University, Ministry of Health of Russia, +7(962)8101752, tishovakseni@mail.ru, https://orcid.org/0000-0003-0886-4471, 656038, Russia, Barnaul, Lenina str., 40.
Ekaterina I. Lebedeva, PhD, Assistant, Department of Obstetrics and Gynecology, Altay State Medical University, Ministry of Health of Russia, mory-ekaterina@yandex.ru, https://orcid.org/0000-0003-2988-5837, 656038, Russia, Barnaul, Lenina str., 40.
Galina V. Nemtseva, PhD, Associate Professor, Department of Obstetrics and Gynecology, Altay State Medical University, Ministry of Health of Russia,
Galya.nemceva@mail.ru, https://orcid.org/0000-0001-8509-6600, 656038, Russia, Barnaul, Lenina str., 40.

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